AU2001267882A1 - Preventives and remedies for diseases in association with demyelination - Google Patents
Preventives and remedies for diseases in association with demyelinationInfo
- Publication number
- AU2001267882A1 AU2001267882A1 AU2001267882A AU6788201A AU2001267882A1 AU 2001267882 A1 AU2001267882 A1 AU 2001267882A1 AU 2001267882 A AU2001267882 A AU 2001267882A AU 6788201 A AU6788201 A AU 6788201A AU 2001267882 A1 AU2001267882 A1 AU 2001267882A1
- Authority
- AU
- Australia
- Prior art keywords
- diseases
- pharmaceutical
- demyelination
- prevention
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A pharmaceutical for prevention and treatment of demyelination-associated neural function impairing diseases, the pharmaceutical containing erythropoietin as an active ingredient, and a method for prevention and treatment of the diseases are provided. The preventive and therapeutic pharmaceutical and method of the present invention protectively act on the survival of oligodendrocytes, which form a myelin sheath, in cerebrovascular dementia typified by multiple sclerosis and Binswanger disease, diseases involving demyelination. The pharmaceutical and method also promote maturation of undifferentiated oligodendrocytes present in the brain, activating remyelination. Through these mechanisms, the pharmaceutical and method can prevent and treat demyelination-associated neural function impairing diseases. <IMAGE>
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000-199421 | 2000-06-30 | ||
JP2000199421 | 2000-06-30 | ||
PCT/JP2001/005641 WO2002002135A1 (en) | 2000-06-30 | 2001-06-29 | Preventives and remedies for diseases in association with demyelination |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001267882A1 true AU2001267882A1 (en) | 2002-01-14 |
Family
ID=18697441
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001267882A Abandoned AU2001267882A1 (en) | 2000-06-30 | 2001-06-29 | Preventives and remedies for diseases in association with demyelination |
Country Status (7)
Country | Link |
---|---|
US (1) | US8039253B2 (en) |
EP (1) | EP1295604B1 (en) |
JP (1) | JP5053499B2 (en) |
AT (1) | ATE444077T1 (en) |
AU (1) | AU2001267882A1 (en) |
DE (1) | DE60140054D1 (en) |
WO (1) | WO2002002135A1 (en) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7820180B2 (en) | 2004-09-24 | 2010-10-26 | The Trustees Of The University Of Pennsylvania | Listeria-based and LLO-based vaccines |
US9006155B2 (en) | 2005-09-09 | 2015-04-14 | Halliburton Energy Services, Inc. | Placing a fluid comprising kiln dust in a wellbore through a bottom hole assembly |
US9809737B2 (en) | 2005-09-09 | 2017-11-07 | Halliburton Energy Services, Inc. | Compositions containing kiln dust and/or biowaste ash and methods of use |
US8505630B2 (en) | 2005-09-09 | 2013-08-13 | Halliburton Energy Services, Inc. | Consolidating spacer fluids and methods of use |
US8403045B2 (en) | 2005-09-09 | 2013-03-26 | Halliburton Energy Services, Inc. | Settable compositions comprising unexpanded perlite and methods of cementing in subterranean formations |
US8307899B2 (en) | 2005-09-09 | 2012-11-13 | Halliburton Energy Services, Inc. | Methods of plugging and abandoning a well using compositions comprising cement kiln dust and pumicite |
US8505629B2 (en) | 2005-09-09 | 2013-08-13 | Halliburton Energy Services, Inc. | Foamed spacer fluids containing cement kiln dust and methods of use |
US8555967B2 (en) | 2005-09-09 | 2013-10-15 | Halliburton Energy Services, Inc. | Methods and systems for evaluating a boundary between a consolidating spacer fluid and a cement composition |
US9676989B2 (en) | 2005-09-09 | 2017-06-13 | Halliburton Energy Services, Inc. | Sealant compositions comprising cement kiln dust and tire-rubber particles and method of use |
US9051505B2 (en) | 2005-09-09 | 2015-06-09 | Halliburton Energy Services, Inc. | Placing a fluid comprising kiln dust in a wellbore through a bottom hole assembly |
US8333240B2 (en) | 2005-09-09 | 2012-12-18 | Halliburton Energy Services, Inc. | Reduced carbon footprint settable compositions for use in subterranean formations |
US9023150B2 (en) | 2005-09-09 | 2015-05-05 | Halliburton Energy Services, Inc. | Acid-soluble cement compositions comprising cement kiln dust and/or a natural pozzolan and methods of use |
US8281859B2 (en) | 2005-09-09 | 2012-10-09 | Halliburton Energy Services Inc. | Methods and compositions comprising cement kiln dust having an altered particle size |
US8297357B2 (en) * | 2005-09-09 | 2012-10-30 | Halliburton Energy Services Inc. | Acid-soluble cement compositions comprising cement kiln dust and/or a natural pozzolan and methods of use |
US8672028B2 (en) | 2010-12-21 | 2014-03-18 | Halliburton Energy Services, Inc. | Settable compositions comprising interground perlite and hydraulic cement |
US8950486B2 (en) | 2005-09-09 | 2015-02-10 | Halliburton Energy Services, Inc. | Acid-soluble cement compositions comprising cement kiln dust and methods of use |
US8522873B2 (en) | 2005-09-09 | 2013-09-03 | Halliburton Energy Services, Inc. | Spacer fluids containing cement kiln dust and methods of use |
US9150773B2 (en) | 2005-09-09 | 2015-10-06 | Halliburton Energy Services, Inc. | Compositions comprising kiln dust and wollastonite and methods of use in subterranean formations |
US8327939B2 (en) | 2005-09-09 | 2012-12-11 | Halliburton Energy Services, Inc. | Settable compositions comprising cement kiln dust and rice husk ash and methods of use |
US8609595B2 (en) | 2005-09-09 | 2013-12-17 | Halliburton Energy Services, Inc. | Methods for determining reactive index for cement kiln dust, associated compositions, and methods of use |
DE102006004008A1 (en) * | 2006-01-27 | 2007-08-02 | Hannelore Prof. Dr. Dr. Ehrenreich | Treating or preventing multiple sclerosis comprises administering erythropoietin for periods separated by intervals in which no erythropoietin is administered |
JPWO2008023725A1 (en) | 2006-08-22 | 2010-01-14 | 中外製薬株式会社 | Prophylactic and / or therapeutic agent for peripheral neuropathy |
WO2009010107A1 (en) | 2007-07-19 | 2009-01-22 | Hannelore Ehrenreich | Use of epo receptor activation or stimulation for the improvement of the edss score in patients with multiple sclerosis |
WO2010092419A1 (en) * | 2009-02-12 | 2010-08-19 | Assistance Publique - Hopitaux De Paris | Combined treatment of multiple sclerosis |
US20170304367A1 (en) * | 2014-10-29 | 2017-10-26 | University Of Utah Research Foundation | Methods of treating hypoxia-associated optical conditions with cartilage oligo matrix protein-angiopoietin 1 (comp-ang1) |
CN115501227B (en) * | 2021-08-02 | 2023-09-19 | 中山大学·深圳 | Application of compound in preparing medicine for preventing and treating demyelinating diseases |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4732889A (en) | 1985-02-06 | 1988-03-22 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical composition for the treatment of the anemia of rheumatoid arthritis |
JP3537151B2 (en) * | 1991-12-26 | 2004-06-14 | 中外製薬株式会社 | Prevention and treatment of diseases due to cerebral dysfunction |
US5700909A (en) * | 1993-07-30 | 1997-12-23 | The Regents Of The University Of California | Prosaposin and cytokine-derived peptides |
TW586933B (en) | 1996-06-20 | 2004-05-11 | Chugai Pharmaceutical Co Ltd | Compositions for treating liver-complaints using EPO |
US6165783A (en) * | 1997-10-24 | 2000-12-26 | Neuro Spheres Holdings Ltd. | Erythropoietin-mediated neurogenesis |
US7410941B1 (en) * | 1999-04-13 | 2008-08-12 | The Kenneth S. Warren Institute, Inc. | Methods for treatment of neurodegenerative conditions by peripherally administered erythropoietin |
CN1607957B (en) | 1999-04-13 | 2012-10-10 | 肯尼思S.沃伦协会有限公司 | Modulation of excitable tissue function by peripherally administered erythropoietin |
JP2001010972A (en) * | 1999-06-30 | 2001-01-16 | Masahiro Sakanaka | Cytoprotective agent comprising peptide relating to prosaposin |
-
2001
- 2001-06-29 AU AU2001267882A patent/AU2001267882A1/en not_active Abandoned
- 2001-06-29 DE DE60140054T patent/DE60140054D1/en not_active Expired - Lifetime
- 2001-06-29 EP EP01945716A patent/EP1295604B1/en not_active Expired - Lifetime
- 2001-06-29 WO PCT/JP2001/005641 patent/WO2002002135A1/en active Application Filing
- 2001-06-29 US US10/312,721 patent/US8039253B2/en not_active Expired - Fee Related
- 2001-06-29 JP JP2002506756A patent/JP5053499B2/en not_active Expired - Fee Related
- 2001-06-29 AT AT01945716T patent/ATE444077T1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US8039253B2 (en) | 2011-10-18 |
EP1295604B1 (en) | 2009-09-30 |
WO2002002135A1 (en) | 2002-01-10 |
JP5053499B2 (en) | 2012-10-17 |
DE60140054D1 (en) | 2009-11-12 |
ATE444077T1 (en) | 2009-10-15 |
EP1295604A4 (en) | 2005-04-27 |
EP1295604A1 (en) | 2003-03-26 |
US20050032682A1 (en) | 2005-02-10 |
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