AU2001266861A1 - Photocleavable prodrugs for selective drug delivery - Google Patents

Photocleavable prodrugs for selective drug delivery

Info

Publication number
AU2001266861A1
AU2001266861A1 AU2001266861A AU6686101A AU2001266861A1 AU 2001266861 A1 AU2001266861 A1 AU 2001266861A1 AU 2001266861 A AU2001266861 A AU 2001266861A AU 6686101 A AU6686101 A AU 6686101A AU 2001266861 A1 AU2001266861 A1 AU 2001266861A1
Authority
AU
Australia
Prior art keywords
photocleavable
prodrugs
drug delivery
selective drug
selective
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001266861A
Inventor
Randell L. Mills
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU2001266861A1 publication Critical patent/AU2001266861A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0042—Photocleavage of drugs in vivo, e.g. cleavage of photolabile linkers in vivo by UV radiation for releasing the pharmacologically-active agent from the administered agent; photothrombosis or photoocclusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/558—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being a chemiluminescent acceptor

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2001266861A 2000-06-12 2001-06-12 Photocleavable prodrugs for selective drug delivery Abandoned AU2001266861A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21103600P 2000-06-12 2000-06-12
US60/211,036 2000-06-12
PCT/US2001/018869 WO2001095944A2 (en) 2000-06-12 2001-06-12 Photocleavable prodrugs for selective drug delivery

Publications (1)

Publication Number Publication Date
AU2001266861A1 true AU2001266861A1 (en) 2001-12-24

Family

ID=22785353

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001266861A Abandoned AU2001266861A1 (en) 2000-06-12 2001-06-12 Photocleavable prodrugs for selective drug delivery

Country Status (3)

Country Link
US (1) US7015352B2 (en)
AU (1) AU2001266861A1 (en)
WO (1) WO2001095944A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001266861A1 (en) * 2000-06-12 2001-12-24 Randell L. Mills Photocleavable prodrugs for selective drug delivery
US20050080260A1 (en) * 2003-04-22 2005-04-14 Mills Randell L. Preparation of prodrugs for selective drug delivery
US7188033B2 (en) 2003-07-21 2007-03-06 Blacklight Power Incorporated Method and system of computing and rendering the nature of the chemical bond of hydrogen-type molecules and molecular ions
PT1660440E (en) * 2003-08-20 2012-05-15 Xenoport Inc Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
EP2354120A1 (en) 2003-08-20 2011-08-10 XenoPort, Inc. Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
US7773656B1 (en) 2003-10-24 2010-08-10 Blacklight Power, Inc. Molecular hydrogen laser
CN100391448C (en) 2003-11-19 2008-06-04 奥加生物药业(I.P.1)有限公司 Materials and methods for improving alcohol metabolism and alleviating the effects of hangovers
TWI350751B (en) 2003-12-19 2011-10-21 Omega Bio Pharma Ip3 Ltd Pharmaceutical compositions for treating diabetes
AU2005240122B2 (en) 2004-05-03 2011-02-17 Omega Bio-Pharma (I.P.3) Limited Cysteamines for treating complications of hypercholesterolemia and diabetes
WO2005116630A2 (en) 2004-05-17 2005-12-08 Blacklight Power, Inc. Method and system of computing and rendering the nature of the excited electronic states of atoms and atomic ions
US10052394B2 (en) 2014-11-21 2018-08-21 General Electric Company Microbubble tether for diagnostic and therapeutic applications

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2839542A (en) * 1955-03-14 1958-06-17 Chalkley Lyman Quaternary ammonium salts of aminotriphenylmethane acetonitriles
US2855303A (en) * 1955-10-24 1958-10-07 Chalkley Lyman Photosensitive system
US2839543A (en) * 1955-12-02 1958-06-17 Chalkley Lyman Process for preparing cyanides of triarylmethane dyes
US2829148A (en) * 1955-12-15 1958-04-01 Chalkley Lyman Purification of cyanides of triarylmethane dyes
US2936235A (en) * 1957-03-27 1960-05-10 Chalkley Lyman Photoactivation of aminotriarylmethane dye cyanides
US3798131A (en) * 1972-04-24 1974-03-19 Pasadena Foundation For Medica Assay for polymeric dna as a method for detecting malignancy
DE2716677C2 (en) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephem derivatives and processes for their preparation
DE3278334D1 (en) 1981-10-23 1988-05-19 Genetics Int Inc Sensor for components of a liquid mixture
GB8311018D0 (en) * 1983-04-22 1983-05-25 Amersham Int Plc Detecting mutations in dna
US4626501A (en) * 1983-09-02 1986-12-02 Integrated Genetics, Inc. Labeled DNA
US4599303A (en) * 1983-12-12 1986-07-08 Hri Associates, Inc. Nucleic acid hybridization assay employing probes crosslinkable to target sequences
GB8405437D0 (en) * 1984-03-01 1984-04-04 Amersham Int Plc Detecting polynucleotide sequences
US4683194A (en) * 1984-05-29 1987-07-28 Cetus Corporation Method for detection of polymorphic restriction sites and nucleic acid sequences
US4625014A (en) * 1984-07-10 1986-11-25 Dana-Farber Cancer Institute, Inc. Cell-delivery agent
US5428163A (en) * 1986-12-31 1995-06-27 Mills; Randell L. Prodrugs for selective drug delivery
US5482719A (en) * 1992-10-30 1996-01-09 Guillet; James E. Drug delivery systems
AU2001266861A1 (en) * 2000-06-12 2001-12-24 Randell L. Mills Photocleavable prodrugs for selective drug delivery

Also Published As

Publication number Publication date
US7015352B2 (en) 2006-03-21
US20030228644A1 (en) 2003-12-11
WO2001095944A2 (en) 2001-12-20
WO2001095944A3 (en) 2002-08-08

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