AU2001266223A1 - Methods and compositions for the treatment of alcoholism and alcohol dependence - Google Patents
Methods and compositions for the treatment of alcoholism and alcohol dependenceInfo
- Publication number
- AU2001266223A1 AU2001266223A1 AU2001266223A AU6622301A AU2001266223A1 AU 2001266223 A1 AU2001266223 A1 AU 2001266223A1 AU 2001266223 A AU2001266223 A AU 2001266223A AU 6622301 A AU6622301 A AU 6622301A AU 2001266223 A1 AU2001266223 A1 AU 2001266223A1
- Authority
- AU
- Australia
- Prior art keywords
- alcoholism
- compositions
- treatment
- methods
- alcohol dependence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 208000007848 Alcoholism Diseases 0.000 title abstract 4
- 201000007930 alcohol dependence Diseases 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Use is disclosed of (a) an AlDH-inhibitory amount of a Trp metabolite, or an analogue or derivative thereof or (b) a bioprecursor thereof, or (c) a potentiator of (a) and/or (b), in the preparation of a medicament for treating alcoholism and/or alcohol dependence.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0016056 | 2000-06-30 | ||
GB0016056A GB0016056D0 (en) | 2000-06-30 | 2000-06-30 | Methods and compositions for the treatment of alcoholism and alcohol dependence |
GB0017345A GB0017345D0 (en) | 2000-07-15 | 2000-07-15 | Methods and compositions for the treatment of alcoholism and alcohol dependence |
GB0017345 | 2000-07-15 | ||
PCT/GB2001/002930 WO2002002091A2 (en) | 2000-06-30 | 2001-07-02 | Methods and compositions for the treatment of alcoholism and alcohol dependence |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001266223A1 true AU2001266223A1 (en) | 2002-01-14 |
Family
ID=26244570
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001266223A Abandoned AU2001266223A1 (en) | 2000-06-30 | 2001-07-02 | Methods and compositions for the treatment of alcoholism and alcohol dependence |
Country Status (7)
Country | Link |
---|---|
US (1) | US8003704B2 (en) |
EP (1) | EP1294377B1 (en) |
JP (1) | JP2004501963A (en) |
AT (1) | ATE528000T1 (en) |
AU (1) | AU2001266223A1 (en) |
ES (1) | ES2375347T3 (en) |
WO (1) | WO2002002091A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0326477D0 (en) * | 2003-11-13 | 2003-12-17 | Shs Int Ltd | Medicaments for use in promoting and maintaining abstinence |
BRPI0820440A2 (en) * | 2007-11-06 | 2015-05-26 | Cv Therapeutics Inc | Aldh-2 inhibitors in the treatment of psychiatric disorders. |
WO2018071814A1 (en) | 2016-10-14 | 2018-04-19 | The Trustees Of Columbia University In The City Of New York | Methods of treating alcohol abuse disorder |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1172154B (en) * | 1981-12-15 | 1987-06-18 | Manetti & Roberts Italo Brit | PIROGLUTAMMIL-TRIPTOFANO AND ITS DERIVATIVES, PROCEDURE FOR ITS PREPARATION AND THERAPEUTIC APPLICATIONS |
US5204369A (en) * | 1991-07-01 | 1993-04-20 | The Endowment For Research In Human Biology | Method for the inhibition of aldh-i useful in the treatment of alcohol dependence or alcohol abuse |
GB9522615D0 (en) * | 1995-11-03 | 1996-01-03 | Pharmacia Spa | 4-Phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibiting activity |
DE69932427T2 (en) | 1998-05-12 | 2007-02-22 | The Endowment for Research in Human Biology, Inc., Boston | METHOD AND TESTS USEFUL IN THE TREATMENT OF ALCOHOL DEPENDENCY OR ABUSE |
-
2001
- 2001-07-02 AT AT01943689T patent/ATE528000T1/en not_active IP Right Cessation
- 2001-07-02 WO PCT/GB2001/002930 patent/WO2002002091A2/en active Application Filing
- 2001-07-02 EP EP01943689A patent/EP1294377B1/en not_active Expired - Lifetime
- 2001-07-02 ES ES01943689T patent/ES2375347T3/en not_active Expired - Lifetime
- 2001-07-02 JP JP2002506713A patent/JP2004501963A/en active Pending
- 2001-07-02 US US10/312,733 patent/US8003704B2/en not_active Expired - Fee Related
- 2001-07-02 AU AU2001266223A patent/AU2001266223A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2002002091A3 (en) | 2002-05-02 |
ATE528000T1 (en) | 2011-10-15 |
ES2375347T3 (en) | 2012-02-29 |
US8003704B2 (en) | 2011-08-23 |
EP1294377B1 (en) | 2011-10-12 |
WO2002002091A2 (en) | 2002-01-10 |
JP2004501963A (en) | 2004-01-22 |
EP1294377A2 (en) | 2003-03-26 |
US20080076796A1 (en) | 2008-03-27 |
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