AU2001263411A1 - Gene recombination and hybrid protein development - Google Patents
Gene recombination and hybrid protein developmentInfo
- Publication number
- AU2001263411A1 AU2001263411A1 AU2001263411A AU6341101A AU2001263411A1 AU 2001263411 A1 AU2001263411 A1 AU 2001263411A1 AU 2001263411 A AU2001263411 A AU 2001263411A AU 6341101 A AU6341101 A AU 6341101A AU 2001263411 A1 AU2001263411 A1 AU 2001263411A1
- Authority
- AU
- Australia
- Prior art keywords
- crossover
- parent
- polymer
- polymers
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B10/00—ICT specially adapted for evolutionary bioinformatics, e.g. phylogenetic tree construction or analysis
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
- G16B30/10—Sequence alignment; Homology search
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
- G16B30/20—Sequence assembly
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Theoretical Computer Science (AREA)
- Evolutionary Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biochemistry (AREA)
- Physiology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20704800P | 2000-05-23 | 2000-05-23 | |
US60/207,048 | 2000-05-23 | ||
US23596000P | 2000-09-27 | 2000-09-27 | |
US60/235,960 | 2000-09-27 | ||
US28356701P | 2001-04-13 | 2001-04-13 | |
US60/283,567 | 2001-04-13 | ||
PCT/US2001/016831 WO2001090346A2 (fr) | 2000-05-23 | 2001-05-23 | Recombinaison de genes et mise au point de proteines hybrides |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001263411A1 true AU2001263411A1 (en) | 2001-12-03 |
Family
ID=27395018
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001263411A Abandoned AU2001263411A1 (en) | 2000-05-23 | 2001-05-23 | Gene recombination and hybrid protein development |
Country Status (5)
Country | Link |
---|---|
US (1) | US20020045175A1 (fr) |
EP (1) | EP1283877A2 (fr) |
AU (1) | AU2001263411A1 (fr) |
CA (1) | CA2405520A1 (fr) |
WO (1) | WO2001090346A2 (fr) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6991922B2 (en) | 1998-08-12 | 2006-01-31 | Proteus S.A. | Process for in vitro creation of recombinant polynucleotide sequences by oriented ligation |
US6951719B1 (en) | 1999-08-11 | 2005-10-04 | Proteus S.A. | Process for obtaining recombined nucleotide sequences in vitro, libraries of sequences and sequences thus obtained |
US6917882B2 (en) * | 1999-01-19 | 2005-07-12 | Maxygen, Inc. | Methods for making character strings, polynucleotides and polypeptides having desired characteristics |
US7024312B1 (en) * | 1999-01-19 | 2006-04-04 | Maxygen, Inc. | Methods for making character strings, polynucleotides and polypeptides having desired characteristics |
US7430477B2 (en) * | 1999-10-12 | 2008-09-30 | Maxygen, Inc. | Methods of populating data structures for use in evolutionary simulations |
EP1272967A2 (fr) * | 2000-03-30 | 2003-01-08 | Maxygen, Inc. | Selection de sites de recombinaison par enjambement in silico |
AU2002251710A1 (en) * | 2000-11-10 | 2002-07-30 | The Penn State Research Foundation | A modeling framework for predicting the number, type, and distribution of crossovers in directed evolution experiments |
JP4776146B2 (ja) | 2001-01-10 | 2011-09-21 | ザ・ペン・ステート・リサーチ・ファンデーション | 細胞代謝をモデル化する方法及びシステム |
US7582423B2 (en) * | 2001-02-02 | 2009-09-01 | Novici Biotech Llc | Population of polynucleotide sequence variants |
US7838219B2 (en) * | 2001-02-02 | 2010-11-23 | Novici Biotech Llc | Method of increasing complementarity in a heteroduplex |
US20040142433A1 (en) * | 2001-02-02 | 2004-07-22 | Padgett Hal S. | Polynucleotide sequence variants |
EP1358322B1 (fr) | 2001-02-02 | 2009-10-28 | Large Scale Biology Corporation | Procede destine a ameliorer la complementarite d'un heteroduplex |
WO2002083868A2 (fr) * | 2001-04-16 | 2002-10-24 | California Institute Of Technology | Variantes d'oxygénase à cytochrome p450 mues par le peroxyde |
WO2002090496A2 (fr) * | 2001-05-03 | 2002-11-14 | Rensselaer Polytechnic Institute | Nouvelles methodes d'evolution dirigee |
US20030157495A1 (en) * | 2002-02-01 | 2003-08-21 | Padgett Hal S. | Nucleic acid molecules encoding CEL I endonuclease and methods of use thereof |
US7078211B2 (en) * | 2002-02-01 | 2006-07-18 | Large Scale Biology Corporation | Nucleic acid molecules encoding endonucleases and methods of use thereof |
US7747391B2 (en) * | 2002-03-01 | 2010-06-29 | Maxygen, Inc. | Methods, systems, and software for identifying functional biomolecules |
ES2564570T3 (es) * | 2002-03-01 | 2016-03-23 | Codexis Mayflower Holdings, Llc | Métodos, sistemas y software para la identificación de biomoléculas funcionales |
US20050084907A1 (en) * | 2002-03-01 | 2005-04-21 | Maxygen, Inc. | Methods, systems, and software for identifying functional biomolecules |
JP4851687B2 (ja) * | 2002-03-09 | 2012-01-11 | マキシジェン, インコーポレイテッド | 定向進化のための交叉点の最適化 |
US20030211484A1 (en) * | 2002-05-13 | 2003-11-13 | Keith Ball | Sequence lineage evaluation interface |
US7826975B2 (en) | 2002-07-10 | 2010-11-02 | The Penn State Research Foundation | Method for redesign of microbial production systems |
WO2004018621A2 (fr) | 2002-07-10 | 2004-03-04 | The Penn State Research Foundation | Procede de determination de strategies d'inactivation genique |
WO2005007806A2 (fr) * | 2003-05-07 | 2005-01-27 | Duke University | Conception de structures de proteine pour reconnaissance et liaison recepteur-ligand |
US7524664B2 (en) | 2003-06-17 | 2009-04-28 | California Institute Of Technology | Regio- and enantioselective alkane hydroxylation with modified cytochrome P450 |
US20050164308A1 (en) * | 2003-12-18 | 2005-07-28 | Fiona Harding | Beta-lactamase CD4+ T-cell epitopes |
US8715988B2 (en) * | 2005-03-28 | 2014-05-06 | California Institute Of Technology | Alkane oxidation by modified hydroxylases |
WO2008016709A2 (fr) * | 2006-08-04 | 2008-02-07 | California Institute Of Technology | Procédés et systèmes de fluoration sélective des molécules organiques |
US8252559B2 (en) * | 2006-08-04 | 2012-08-28 | The California Institute Of Technology | Methods and systems for selective fluorination of organic molecules |
US20120171693A1 (en) * | 2007-01-05 | 2012-07-05 | The California Institute Of Technology | Methods for Generating Novel Stabilized Proteins |
WO2008121435A2 (fr) * | 2007-02-02 | 2008-10-09 | The California Institute Of Technology | Procédés pour générer de nouvelles protéines stabilisées |
US20080268517A1 (en) * | 2007-02-08 | 2008-10-30 | The California Institute Of Technology | Stable, functional chimeric cytochrome p450 holoenzymes |
US8802401B2 (en) * | 2007-06-18 | 2014-08-12 | The California Institute Of Technology | Methods and compositions for preparation of selectively protected carbohydrates |
WO2009149218A2 (fr) * | 2008-06-03 | 2009-12-10 | Codon Devices, Inc. | Nouvelles protéines et procédés de conception et d'utilisation de celles-ci |
WO2013016207A2 (fr) | 2011-07-22 | 2013-01-31 | California Institute Of Technology | Variantes d'enzymes fongiques cel6 stables |
LT2951579T (lt) | 2013-01-31 | 2024-05-27 | Codexis, Inc. | Biomolekulių identifikavimo naudojant multiplikacinės formos modelius būdai, sistemos ir programinė įranga |
USD815146S1 (en) * | 2016-03-25 | 2018-04-10 | Illimina, Inc. | Display screen with application icon |
USD815145S1 (en) * | 2016-03-25 | 2018-04-10 | Illumina, Inc. | Display screen with application icon |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6395547B1 (en) * | 1994-02-17 | 2002-05-28 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
US6117679A (en) * | 1994-02-17 | 2000-09-12 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
CA2284097A1 (fr) * | 1997-03-18 | 1998-09-24 | Novo Nordisk A/S | Rearrangement de sequences d'adn heterologues |
US6365408B1 (en) * | 1998-06-19 | 2002-04-02 | Maxygen, Inc. | Methods of evolving a polynucleotides by mutagenesis and recombination |
EP1105472A2 (fr) * | 1998-08-12 | 2001-06-13 | Pangene Corporation | Evolution genique specifique du domaine |
AU1199000A (en) * | 1998-09-29 | 2000-04-17 | Maxygen, Inc. | Shuffling of codon altered genes |
US20020072864A1 (en) * | 1999-08-31 | 2002-06-13 | Emmanuel Lacroix | Computer-based method for macromolecular engineering and design |
WO2001061344A1 (fr) * | 2000-02-17 | 2001-08-23 | California Institute Of Technology | Conception evolutive a ciblage computationnel |
-
2001
- 2001-05-23 US US09/863,765 patent/US20020045175A1/en not_active Abandoned
- 2001-05-23 CA CA002405520A patent/CA2405520A1/fr not_active Abandoned
- 2001-05-23 WO PCT/US2001/016831 patent/WO2001090346A2/fr not_active Application Discontinuation
- 2001-05-23 EP EP01937702A patent/EP1283877A2/fr not_active Withdrawn
- 2001-05-23 AU AU2001263411A patent/AU2001263411A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2405520A1 (fr) | 2001-11-29 |
WO2001090346A2 (fr) | 2001-11-29 |
US20020045175A1 (en) | 2002-04-18 |
EP1283877A2 (fr) | 2003-02-19 |
WO2001090346A3 (fr) | 2002-10-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |