AU2001262974A1 - Dna alkylating agent and activation thereof - Google Patents

Dna alkylating agent and activation thereof

Info

Publication number
AU2001262974A1
AU2001262974A1 AU2001262974A AU6297401A AU2001262974A1 AU 2001262974 A1 AU2001262974 A1 AU 2001262974A1 AU 2001262974 A AU2001262974 A AU 2001262974A AU 6297401 A AU6297401 A AU 6297401A AU 2001262974 A1 AU2001262974 A1 AU 2001262974A1
Authority
AU
Australia
Prior art keywords
activation
alkylating agent
dna alkylating
dna
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001262974A
Inventor
Dale L Boger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Publication of AU2001262974A1 publication Critical patent/AU2001262974A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
AU2001262974A 2000-05-03 2001-05-03 Dna alkylating agent and activation thereof Abandoned AU2001262974A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20154300P 2000-05-03 2000-05-03
US60201543 2000-05-03
PCT/US2001/014374 WO2001083482A1 (en) 2000-05-03 2001-05-03 Dna alkylating agent and activation thereof

Publications (1)

Publication Number Publication Date
AU2001262974A1 true AU2001262974A1 (en) 2001-11-12

Family

ID=22746258

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001262974A Abandoned AU2001262974A1 (en) 2000-05-03 2001-05-03 Dna alkylating agent and activation thereof

Country Status (2)

Country Link
AU (1) AU2001262974A1 (en)
WO (1) WO2001083482A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1363908A4 (en) * 2001-01-24 2004-05-06 Auckland Uniservices Ltd ANTI-CANCER 2,3-DIHYDRO-1H-PYRROLO 3,2-f]QUINOLINE COMPLEXES OF COBALT AND CHROMIUM
NZ529788A (en) 2001-05-31 2003-12-19 Medarex Inc Cytotoxins, prodrugs, linkers and stabilizers useful therefor
GB0619325D0 (en) 2006-09-30 2006-11-08 Univ Strathclyde New compounds
TWI412367B (en) 2006-12-28 2013-10-21 Medarex Llc Chemical linkers and cleavable substrates and conjugates thereof
KR20090122439A (en) 2007-02-21 2009-11-30 메다렉스, 인코포레이티드 Chemical linkers with single amino acids and conjugates thereof
US9901567B2 (en) 2007-08-01 2018-02-27 Syntarga B.V. Substituted CC-1065 analogs and their conjugates
NO2344478T3 (en) 2008-11-03 2018-02-24
LT2560645T (en) 2010-04-21 2016-10-10 Syntarga B.V. Conjugates of cc-1065 analogs and bifunctional linkers
WO2014016202A1 (en) * 2012-07-22 2014-01-30 Universität Basel Methods for catalytic alkylation of nucleic acids
CN102827061A (en) * 2012-09-19 2012-12-19 兰州大学 5,6,7- trimethoxy indole derivative, preparation method and use thereof
PT3092010T (en) 2014-01-10 2018-09-28 Synthon Biopharmaceuticals Bv Method for purifying cys-linked antibody-drug conjugates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4912227A (en) * 1984-02-21 1990-03-27 The Upjohn Company 1,2,8,8A-tetrahydrocyclopropa(c)pyrrolo(3,2-e)-indol-4-(5H)-ones and related compounds
CA2313231A1 (en) * 1997-12-08 1999-06-17 The Scripps Research Institute Synthesis of cc-1065/duocarmycin analogs

Also Published As

Publication number Publication date
WO2001083482A1 (en) 2001-11-08

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