AU2001260661A1 - Compounds exhibiting thrombopoietin-like activities - Google Patents
Compounds exhibiting thrombopoietin-like activitiesInfo
- Publication number
- AU2001260661A1 AU2001260661A1 AU2001260661A AU6066101A AU2001260661A1 AU 2001260661 A1 AU2001260661 A1 AU 2001260661A1 AU 2001260661 A AU2001260661 A AU 2001260661A AU 6066101 A AU6066101 A AU 6066101A AU 2001260661 A1 AU2001260661 A1 AU 2001260661A1
- Authority
- AU
- Australia
- Prior art keywords
- activities
- compounds exhibiting
- exhibiting thrombopoietin
- thrombopoietin
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000161036 | 2000-05-30 | ||
JP2000-161036 | 2000-05-30 | ||
PCT/JP2001/004561 WO2001092211A1 (en) | 2000-05-30 | 2001-05-30 | Compounds exhibiting thrombopoietin-like activities |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001260661A1 true AU2001260661A1 (en) | 2001-12-11 |
Family
ID=18665138
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001260661A Abandoned AU2001260661A1 (en) | 2000-05-30 | 2001-05-30 | Compounds exhibiting thrombopoietin-like activities |
Country Status (6)
Country | Link |
---|---|
US (1) | US6887890B2 (en) |
EP (1) | EP1291341A4 (en) |
JP (1) | JP3966816B2 (en) |
AU (1) | AU2001260661A1 (en) |
TW (1) | TWI282785B (en) |
WO (1) | WO2001092211A1 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004096154A2 (en) | 2003-04-29 | 2004-11-11 | Smithkline Beecham Corporation | Methods for treating degenerative diseases/injuries |
WO2007044982A2 (en) * | 2005-10-13 | 2007-04-19 | Smithkline Beecham Corporation | Methods for the preservation of platelet efficacy during storage |
CA2630234A1 (en) * | 2005-11-23 | 2007-05-31 | Ligand Pharmaceuticals Inc. | Thrombopoietin activity modulating compounds and methods |
US7879318B2 (en) | 2006-01-23 | 2011-02-01 | Mcw Research Foundation, Inc. | Method of reducing the effects of ischemia by administration of a thrombopoietin receptor ligand |
EP2079687A1 (en) * | 2006-12-18 | 2009-07-22 | Ambrx, Inc. | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides |
US20110129550A1 (en) * | 2007-02-16 | 2011-06-02 | Connie Erickson-Miller | Cancer treatment method |
US20110160130A1 (en) * | 2007-02-16 | 2011-06-30 | Connie Erickson-Miller | Cancer treatment method |
UY30915A1 (en) * | 2007-02-16 | 2008-09-02 | Smithkline Beecham Corp | CANCER TREATMENT METHOD |
KR101530402B1 (en) * | 2007-10-09 | 2015-06-19 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | Thrombopoietin receptor agonist (tpora) kills acute human myeloid leukemia cells |
US8476249B2 (en) | 2009-05-07 | 2013-07-02 | Glaxosmithkline Llc | Method of treating thrombocytopenia |
PT2488486T (en) * | 2009-10-13 | 2019-11-05 | Ligand Pharm Inc | Hematopoietic growth factor mimetic small molecule compounds and their uses |
MX2018003301A (en) | 2015-09-17 | 2019-02-07 | Pcna inhibitors. |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3415103A1 (en) | 1984-04-21 | 1985-10-31 | Bayer Ag, 5090 Leverkusen | METHOD FOR FLUORESCENT EXTINGUISHING AND NEW CATIONIC AROMATIC NITRO COMPOUNDS |
JPH01261650A (en) * | 1988-04-13 | 1989-10-18 | Canon Inc | Electrophotographic sensitive body |
NZ310778A (en) | 1995-06-07 | 1999-10-28 | Glaxo Group Ltd | Peptides and compounds that bind to a thrombopoietin receptor |
JPH10212289A (en) | 1997-01-31 | 1998-08-11 | Kyowa Hakko Kogyo Co Ltd | Pyrrolophenanthridine derivative |
JPH111477A (en) | 1997-06-12 | 1999-01-06 | Hokuriku Seiyaku Co Ltd | 1,4-benzodiazepine and use thereof |
JPH11152276A (en) | 1997-11-20 | 1999-06-08 | Hokuriku Seiyaku Co Ltd | Benzodiazepine derivative |
ATE315390T1 (en) | 1998-11-17 | 2006-02-15 | Smithkline Beecham Corp | CYCLIC POLYAMINES FOR THE TREATMENT OF THROMBOCYTOPENIA |
GC0000177A (en) | 1998-12-17 | 2006-03-29 | Smithkline Beecham | Thrombopoietin mimetics |
WO2000066112A1 (en) | 1999-05-03 | 2000-11-09 | Smithkline Beecham Corporation | Cxcr-4 receptor antagonists - thrombopoietin mimetics |
KR20020069183A (en) | 1999-07-26 | 2002-08-29 | 시오노기세이야쿠가부시키가이샤 | Drug compositions exhibiting thrombopoietin agonism |
JP4488663B2 (en) | 1999-09-10 | 2010-06-23 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | Thrombopoietin mimetic |
DE60032783T2 (en) | 1999-09-24 | 2007-12-06 | Smithkline Beecham Corp. | THROMBOPOIETINMIMETIKA |
AU1462201A (en) | 1999-11-05 | 2001-06-06 | Smithkline Beecham Corporation | Semicarbazone derivatives and their use as thrombopoietin mimetics |
-
2001
- 2001-05-30 WO PCT/JP2001/004561 patent/WO2001092211A1/en active Application Filing
- 2001-05-30 JP JP2002500826A patent/JP3966816B2/en not_active Expired - Fee Related
- 2001-05-30 AU AU2001260661A patent/AU2001260661A1/en not_active Abandoned
- 2001-05-30 US US10/296,638 patent/US6887890B2/en not_active Expired - Fee Related
- 2001-05-30 TW TW090113028A patent/TWI282785B/en not_active IP Right Cessation
- 2001-05-30 EP EP01934428A patent/EP1291341A4/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
WO2001092211A1 (en) | 2001-12-06 |
US6887890B2 (en) | 2005-05-03 |
US20030162724A1 (en) | 2003-08-28 |
EP1291341A1 (en) | 2003-03-12 |
EP1291341A4 (en) | 2005-04-27 |
TWI282785B (en) | 2007-06-21 |
JP3966816B2 (en) | 2007-08-29 |
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