AU2001260519A1 - Radiopharmaceutical products suitable for the selective labeling of lymphocytes,and their preparation - Google Patents

Radiopharmaceutical products suitable for the selective labeling of lymphocytes,and their preparation

Info

Publication number
AU2001260519A1
AU2001260519A1 AU2001260519A AU6051901A AU2001260519A1 AU 2001260519 A1 AU2001260519 A1 AU 2001260519A1 AU 2001260519 A AU2001260519 A AU 2001260519A AU 6051901 A AU6051901 A AU 6051901A AU 2001260519 A1 AU2001260519 A1 AU 2001260519A1
Authority
AU
Australia
Prior art keywords
products suitable
lymphocytes
preparation
selective labeling
radiopharmaceutical products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001260519A
Inventor
Emmanuel Bellande
Franck Mevellec
Nicolas Noiret
Roberto Pasqualini
Henri Patin
Alain Roucoux
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
CIS Bio International SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CIS Bio International SA filed Critical CIS Bio International SA
Publication of AU2001260519A1 publication Critical patent/AU2001260519A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1203—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules in a form not provided for by groups A61K51/1206 - A61K51/1296, e.g. cells, cell fragments, viruses, virus capsides, ghosts, red blood cells, viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention concerns radiopharmaceutical products suitable for the selective labeling of lymphomas containing a metal complex with the formula:in which M is chosen from among 99mTc, 186Re and 188Re, and R1 represents an alkyl, cycloalkyl, aralkyl or aryl group, optionally substituted, obtained by reaction of a pertechnetate or a perrhenate with a reducing agent such as SnCl2ZP2O in the presence of a dithiocarboxylate having the formula: (R1CS2)-Z2+.
AU2001260519A 2000-05-23 2001-05-14 Radiopharmaceutical products suitable for the selective labeling of lymphocytes,and their preparation Abandoned AU2001260519A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR0006549A FR2809401B1 (en) 2000-05-23 2000-05-23 RADIOPHARMACEUTICAL PRODUCTS USEFUL FOR THE SELECTIVE MARKING OF LYMPHOCYTES AND THEIR PREPARATION
FR0006549 2000-05-23
US09/584,108 US6469146B1 (en) 2000-05-23 2000-05-31 Radiopharmaceutical products suitable for the selective labeling of lymphocytes, and their preparation
PCT/IB2001/000825 WO2001090114A1 (en) 2000-05-23 2001-05-14 Radiopharmaceutical products suitable for the selective labeling of lymphocytes, and their preparation

Publications (1)

Publication Number Publication Date
AU2001260519A1 true AU2001260519A1 (en) 2001-12-03

Family

ID=26212417

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001260519A Abandoned AU2001260519A1 (en) 2000-05-23 2001-05-14 Radiopharmaceutical products suitable for the selective labeling of lymphocytes,and their preparation

Country Status (13)

Country Link
US (1) US6469146B1 (en)
EP (1) EP1283842B1 (en)
JP (1) JP2003534348A (en)
AT (1) ATE256690T1 (en)
AU (1) AU2001260519A1 (en)
DE (1) DE60101574T2 (en)
DK (1) DK1283842T3 (en)
ES (1) ES2213115T3 (en)
FR (1) FR2809401B1 (en)
NO (1) NO20025473L (en)
PT (1) PT1283842E (en)
TR (1) TR200400533T4 (en)
WO (1) WO2001090114A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2832408B1 (en) * 2001-11-20 2005-07-15 Schering Ag COMPLEXES OF TECHNETIUM OR RHENIUM, RADIOPHARMACEUTICAL PRODUCTS CONTAINING THEM AND THEIR PREPARATION
WO2008098374A1 (en) * 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab i inhibitors
FR2956325B1 (en) * 2010-02-18 2013-03-15 Enscr THERAPEUTIC DOSE RADIOMARKETING WITH RHENIUM-188 AND AUTOMATION THEREOF, IN PARTICULAR FOR THE TREATMENT OF LIVER CANCER

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698272B1 (en) 1992-11-20 1994-12-30 Cis Bio Int Cell labeling process using nitruro-bis (dithiocarbamato) Tc-99m complexes and kit for carrying out this process.

Also Published As

Publication number Publication date
DE60101574T2 (en) 2004-09-16
DE60101574D1 (en) 2004-01-29
DK1283842T3 (en) 2004-04-13
ATE256690T1 (en) 2004-01-15
PT1283842E (en) 2004-04-30
EP1283842B1 (en) 2003-12-17
FR2809401A1 (en) 2001-11-30
JP2003534348A (en) 2003-11-18
US6469146B1 (en) 2002-10-22
NO20025473L (en) 2003-01-21
EP1283842A1 (en) 2003-02-19
ES2213115T3 (en) 2004-08-16
FR2809401B1 (en) 2004-01-02
WO2001090114A1 (en) 2001-11-29
TR200400533T4 (en) 2004-04-21
NO20025473D0 (en) 2002-11-15

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