AU2001259195A1 - Compounds having affinity for the vascular endothelial growth factor receptor-2 (vegfr-2) and associated uses - Google Patents

Compounds having affinity for the vascular endothelial growth factor receptor-2 (vegfr-2) and associated uses

Info

Publication number
AU2001259195A1
AU2001259195A1 AU2001259195A AU5919501A AU2001259195A1 AU 2001259195 A1 AU2001259195 A1 AU 2001259195A1 AU 2001259195 A AU2001259195 A AU 2001259195A AU 5919501 A AU5919501 A AU 5919501A AU 2001259195 A1 AU2001259195 A1 AU 2001259195A1
Authority
AU
Australia
Prior art keywords
vegfr
affinity
compounds
growth factor
vascular endothelial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001259195A
Inventor
Palani Balu
Min-Jia Chen
Cecilia A. Mozsgai
Sunila Piplani
Peter Joseph Schatz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of AU2001259195A1 publication Critical patent/AU2001259195A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AU2001259195A 2000-04-28 2001-04-27 Compounds having affinity for the vascular endothelial growth factor receptor-2 (vegfr-2) and associated uses Abandoned AU2001259195A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56147000A 2000-04-28 2000-04-28
US09/561,470 2000-04-28
PCT/US2001/013598 WO2001083693A2 (en) 2000-04-28 2001-04-27 Compounds having affinity for the vascular endothelial growth factor receptor-2 (vegfr-2) and associated uses

Publications (1)

Publication Number Publication Date
AU2001259195A1 true AU2001259195A1 (en) 2001-11-12

Family

ID=24242110

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001259195A Abandoned AU2001259195A1 (en) 2000-04-28 2001-04-27 Compounds having affinity for the vascular endothelial growth factor receptor-2 (vegfr-2) and associated uses

Country Status (2)

Country Link
AU (1) AU2001259195A1 (en)
WO (1) WO2001083693A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2279757A3 (en) 2000-06-02 2011-08-03 Bracco Suisse SA Compounds for targeting endothelial cells
US8263739B2 (en) 2000-06-02 2012-09-11 Bracco Suisse Sa Compounds for targeting endothelial cells, compositions containing the same and methods for their use
US7261876B2 (en) 2002-03-01 2007-08-28 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
EP1587944A4 (en) 2002-03-01 2007-03-21 Dyax Corp Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy
US7794693B2 (en) 2002-03-01 2010-09-14 Bracco International B.V. Targeting vector-phospholipid conjugates
US8623822B2 (en) 2002-03-01 2014-01-07 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
NO20026285D0 (en) * 2002-12-30 2002-12-30 Amersham Health As New peptides
SI2949658T1 (en) 2003-03-03 2018-10-30 Dyax Corp. Peptides that specifically bind HGF receptor (cMet) and uses thereof
WO2006044614A2 (en) * 2004-10-14 2006-04-27 Sopherion Therapeutics, Inc. Anti-angiogenic peptides and methods of use thereof
AU2008291296B2 (en) * 2007-08-24 2014-02-06 Julius-Maximilians-Universitat Wurzburg Mutant double cyclized receptor peptides inhibiting beta1-adrenoceptor antibodies
DE102010026061A1 (en) * 2010-06-30 2012-01-05 Siemens Aktiengesellschaft 11C-labeled peptide for detection of a tumor expressing a Her2 / neu receptor
DE102010026063A1 (en) * 2010-06-30 2012-01-05 Siemens Aktiengesellschaft 11C-labeled peptide for the detection of a diseased tissue
DE102010026064A1 (en) * 2010-06-30 2012-01-05 Siemens Aktiengesellschaft 11C-labeled peptide for the detection of a diseased tissue
EP2541193A1 (en) 2011-06-27 2013-01-02 Hexagon Technology Center GmbH Interferometric distance measuring method for measuring surfaces and corresponding measuring apparatus

Also Published As

Publication number Publication date
WO2001083693A8 (en) 2002-01-31
WO2001083693A3 (en) 2003-04-10
WO2001083693A2 (en) 2001-11-08

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