AU2001258568A1 - Ligands specific for an isoform of the prion protein - Google Patents

Ligands specific for an isoform of the prion protein

Info

Publication number
AU2001258568A1
AU2001258568A1 AU2001258568A AU5856801A AU2001258568A1 AU 2001258568 A1 AU2001258568 A1 AU 2001258568A1 AU 2001258568 A AU2001258568 A AU 2001258568A AU 5856801 A AU5856801 A AU 5856801A AU 2001258568 A1 AU2001258568 A1 AU 2001258568A1
Authority
AU
Australia
Prior art keywords
isoform
prion protein
ligands specific
ligands
specific
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001258568A
Inventor
William Siward James
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford University Innovation Ltd
Original Assignee
Oxford University Innovation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford University Innovation Ltd filed Critical Oxford University Innovation Ltd
Publication of AU2001258568A1 publication Critical patent/AU2001258568A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AU2001258568A 2000-05-18 2001-05-18 Ligands specific for an isoform of the prion protein Abandoned AU2001258568A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0012054 2000-05-18
GBGB0012054.3A GB0012054D0 (en) 2000-05-18 2000-05-18 Ligands
PCT/GB2001/002228 WO2001088123A1 (en) 2000-05-18 2001-05-18 Ligands specific for an isoform of the prion protein

Publications (1)

Publication Number Publication Date
AU2001258568A1 true AU2001258568A1 (en) 2001-11-26

Family

ID=9891880

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001258568A Abandoned AU2001258568A1 (en) 2000-05-18 2001-05-18 Ligands specific for an isoform of the prion protein

Country Status (6)

Country Link
US (1) US20030162225A1 (en)
EP (1) EP1287126A1 (en)
AU (1) AU2001258568A1 (en)
CA (1) CA2410028A1 (en)
GB (1) GB0012054D0 (en)
WO (1) WO2001088123A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002226571A1 (en) * 2001-01-29 2002-08-12 Isis Innovation Limited Biligands
AU2002225234A1 (en) * 2001-01-29 2002-08-12 Isis Innovation Limited Streptavidin aptamere
GB0214007D0 (en) * 2002-06-18 2002-07-31 Common Services Agency Removal of prion infectivity
CN1694959B (en) * 2002-09-13 2013-09-18 雷普利瑟公司 Non-sequence complementary antiviral oligonucleotides
US20050196382A1 (en) * 2002-09-13 2005-09-08 Replicor, Inc. Antiviral oligonucleotides targeting viral families
GB0225833D0 (en) * 2002-11-06 2002-12-11 Univ Leeds Nucleic acid ligands and uses therefor
EP1667695A4 (en) * 2003-09-11 2007-01-31 Replicor Inc Oligonucleotides targeting prion diseases
US20070123480A1 (en) * 2003-09-11 2007-05-31 Replicor Inc. Oligonucleotides targeting prion diseases
JP2008507277A (en) * 2004-07-23 2008-03-13 （オーエスアイ）アイテツク・インコーポレーテツド Sequencing of modified nucleic acid molecules
WO2014008440A2 (en) 2012-07-04 2014-01-09 Aptrix Biosystems LLC Aptamers for prion diagnostics and aptamer binding detection system

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0862653B1 (en) * 1995-10-26 2002-01-16 Winnacker, Ernst-Ludwig, Prof. NUCLEIC ACID MOLECULES CAPABLE OF DISTINGUISHING THE ISOFORMS PrPc AND PrPSc OF PRION PROTEINS AND PROCESSES FOR THEIR PRODUCTION
US5998148A (en) * 1999-04-08 1999-12-07 Isis Pharmaceuticals Inc. Antisense modulation of microtubule-associated protein 4 expression
DE19925073C2 (en) * 1999-06-01 2001-07-19 Stefan Weiss Nucleic acid molecules with specific recognition of native PrP · S ·· c ·, production and use

Also Published As

Publication number Publication date
WO2001088123A1 (en) 2001-11-22
GB0012054D0 (en) 2000-07-12
CA2410028A1 (en) 2001-11-22
EP1287126A1 (en) 2003-03-05
US20030162225A1 (en) 2003-08-28

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