AU2001251662A1 - Benzoxazines for use in the treatment of parkinson's disease - Google Patents

Benzoxazines for use in the treatment of parkinson's disease

Info

Publication number
AU2001251662A1
AU2001251662A1 AU2001251662A AU5166201A AU2001251662A1 AU 2001251662 A1 AU2001251662 A1 AU 2001251662A1 AU 2001251662 A AU2001251662 A AU 2001251662A AU 5166201 A AU5166201 A AU 5166201A AU 2001251662 A1 AU2001251662 A1 AU 2001251662A1
Authority
AU
Australia
Prior art keywords
benzoxazines
parkinson
disease
treatment
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001251662A
Inventor
Corinne Elizabeth Augelli-Szafran
Thomas Boehme
Roy Douville Schwarz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of AU2001251662A1 publication Critical patent/AU2001251662A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Benzoxazines of Formula (I) wherein R<1 >is C1-C6 alkyl, C2-C6 alkenyl, or (CH2)n phenyl, R<2 >is C3-C6 alkyl, R<3 >is hydrogen, halo, hydroxy, alkoxy, or alkylthio, R<4 >is hydrogen or alkyl, or a pharmaceutically acceptable salt thereof, are useful for treating movement disorders such as Parkinson's disease.
AU2001251662A 2000-05-09 2001-04-17 Benzoxazines for use in the treatment of parkinson's disease Abandoned AU2001251662A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20278700P 2000-05-09 2000-05-09
US60202787 2000-05-09
PCT/US2001/012528 WO2001085734A1 (en) 2000-05-09 2001-04-17 Benzoxazines for use in the treatment of parkinson's disease

Publications (1)

Publication Number Publication Date
AU2001251662A1 true AU2001251662A1 (en) 2001-11-20

Family

ID=22751255

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001251662A Abandoned AU2001251662A1 (en) 2000-05-09 2001-04-17 Benzoxazines for use in the treatment of parkinson's disease

Country Status (13)

Country Link
US (1) US6812228B2 (en)
EP (1) EP1282625B1 (en)
JP (1) JP2003532733A (en)
AT (1) ATE270295T1 (en)
AU (1) AU2001251662A1 (en)
BR (1) BR0110643A (en)
CA (1) CA2407789A1 (en)
DE (1) DE60104110T2 (en)
DK (1) DK1282625T3 (en)
ES (1) ES2223824T3 (en)
MX (1) MXPA02010270A (en)
PT (1) PT1282625E (en)
WO (1) WO2001085734A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI608886B (en) 2011-07-05 2017-12-21 電子科學工業股份有限公司 Systems and methods for providing temperature stability of acousto-optic beam deflectors and acousto-optic modulators during use
US9463186B2 (en) 2013-04-15 2016-10-11 Northwestern University Treatment for dopaminergic disorders

Also Published As

Publication number Publication date
EP1282625A1 (en) 2003-02-12
EP1282625B1 (en) 2004-06-30
BR0110643A (en) 2003-03-18
PT1282625E (en) 2004-10-29
DE60104110D1 (en) 2004-08-05
MXPA02010270A (en) 2003-04-25
ES2223824T3 (en) 2005-03-01
JP2003532733A (en) 2003-11-05
US20030220335A1 (en) 2003-11-27
ATE270295T1 (en) 2004-07-15
WO2001085734A1 (en) 2001-11-15
DK1282625T3 (en) 2004-11-15
CA2407789A1 (en) 2001-11-15
DE60104110T2 (en) 2005-08-25
US6812228B2 (en) 2004-11-02

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