AU2001242328A1 - Formulations of active components in the form of a solid dispersion - Google Patents

Formulations of active components in the form of a solid dispersion

Info

Publication number
AU2001242328A1
AU2001242328A1 AU2001242328A AU4232801A AU2001242328A1 AU 2001242328 A1 AU2001242328 A1 AU 2001242328A1 AU 2001242328 A AU2001242328 A AU 2001242328A AU 4232801 A AU4232801 A AU 4232801A AU 2001242328 A1 AU2001242328 A1 AU 2001242328A1
Authority
AU
Australia
Prior art keywords
solid dispersion
formulations
active components
solid
carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001242328A
Inventor
Bernhard Lippold
Nora Anne Urbanetz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Knoll GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7627157&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2001242328(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Knoll GmbH filed Critical Knoll GmbH
Publication of AU2001242328A1 publication Critical patent/AU2001242328A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Formulations of active compounds in the form of a solid dispersion, where the solid dispersion is formed from at least one active component and a carrier characterized in that the carrier is a mixture of polyvinylpyrrolidone (PVP) with a weight average molecular weight of ≰1 500 000 Da and of a polyethylene glycol (PEG) which is semi-solid or solid at temperatures of 17 to 22° C. and has an average molar mass of 950 to 3300 Da.
AU2001242328A 2000-01-11 2001-04-10 Formulations of active components in the form of a solid dispersion Abandoned AU2001242328A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10000792A DE10000792A1 (en) 2000-01-11 2000-01-11 Formulations of active substances in the form of a solid dispersion
DE10000792 2000-01-11
PCT/EP2001/000224 WO2001051025A2 (en) 2000-01-11 2001-01-10 Formulations of active components in the form of a solid dispersion

Publications (1)

Publication Number Publication Date
AU2001242328A1 true AU2001242328A1 (en) 2001-07-24

Family

ID=7627157

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001242328A Abandoned AU2001242328A1 (en) 2000-01-11 2001-04-10 Formulations of active components in the form of a solid dispersion

Country Status (9)

Country Link
US (1) US8021688B2 (en)
EP (1) EP1246611B1 (en)
AT (1) ATE373470T1 (en)
AU (1) AU2001242328A1 (en)
CA (1) CA2396722C (en)
DE (2) DE10000792A1 (en)
DK (1) DK1246611T3 (en)
ES (1) ES2293982T3 (en)
WO (1) WO2001051025A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10026698A1 (en) 2000-05-30 2001-12-06 Basf Ag Self-emulsifying active ingredient formulation and use of this formulation
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
AU2005321346B2 (en) * 2004-12-30 2011-06-23 Pierre Fabre Medicament Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it
FR2880274B1 (en) * 2004-12-30 2007-04-13 Pierre Fabre Medicament Sa STABLE SOLID DISPERSION OF VINCA ALKALOID DERIVATIVE AND PROCESS FOR PRODUCING THE SAME
CN104023710A (en) 2011-12-21 2014-09-03 拜耳知识产权有限责任公司 Preparations containing amorphous emodepside
CN103271902B (en) * 2013-05-07 2015-11-11 西安交通大学 A kind of insoluble medicine solid dispersoid and preparation method thereof
CN109481411B (en) * 2017-09-13 2021-02-02 亚宝药业集团股份有限公司 Hot-melt extrusion solid dispersion of nimodipine and preparation method of tablet thereof
CN114699373B (en) * 2022-03-30 2023-03-17 山东新时代药业有限公司 Metoclopramide solid dispersion and preparation method thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4291015A (en) * 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
US4292104A (en) * 1979-09-13 1981-09-29 Corning Glass Works Decalcomania manufacture
US4321263A (en) * 1980-09-30 1982-03-23 Rowell Laboratories, Inc. Psyllium compositions
US4764378A (en) * 1986-02-10 1988-08-16 Zetachron, Inc. Buccal drug dosage form
DE3839825A1 (en) * 1988-11-25 1990-06-13 Henning Berlin Gmbh SOLIDS DISPERSIONS CONTAIN OXIPURINOL AND / OR ITS ALKALI OR EARTH ALKALISALZE
US5368864A (en) * 1988-11-25 1994-11-29 Henning Berlin Gmbh Chemie- Und Pharmawerk Formulation of oxypurinol and/or its alkali and alkaline earth salts
US5080471A (en) * 1990-04-06 1992-01-14 Eic Laboratories, Inc. Electrochromic material and electro-optical device using same
JP2696438B2 (en) * 1991-04-22 1998-01-14 富士写真フイルム株式会社 Photothermographic material
AU671811B2 (en) * 1991-12-18 1996-09-12 Warner-Lambert Company A process for the preparation of a solid dispersion
US5294615A (en) * 1993-04-29 1994-03-15 Abbott Laboratories Terazosin polymorph and pharmaceutical composition
US5599583A (en) * 1994-05-27 1997-02-04 Micro Flo Company Encapsulation with water soluble polymer
KR100239799B1 (en) * 1995-01-21 2000-02-01 손경식 Cyclosporin a solid micelle dispersion for oral administration, the preparation method thereof and its solid dosage form
US5637319A (en) * 1995-03-01 1997-06-10 Takada; Kanji Controlled-release preparations
US6391338B1 (en) * 1995-09-07 2002-05-21 Biovail Technologies Ltd. System for rendering substantially non-dissoluble bio-affecting agents bio-available
DE19701949A1 (en) * 1997-01-13 1998-07-16 Jenapharm Gmbh Transdermal therapeutic system
US5955475A (en) * 1997-06-30 1999-09-21 Endo Pharmaceuticals Inc. Process for manufacturing paroxetine solid dispersions
US6086915A (en) * 1998-04-01 2000-07-11 Bioresponse L.L.C. Compositions and methods of adjusting steroid hormone metabolism through phytochemicals
US6168805B1 (en) * 1998-05-07 2001-01-02 Endo Pharmaceuticals, Inc. Aqueous process for manufacturing paroxetine solid dispersions

Also Published As

Publication number Publication date
US20030109639A1 (en) 2003-06-12
CA2396722C (en) 2008-08-19
EP1246611B1 (en) 2007-09-19
DE10000792A1 (en) 2001-07-19
DE50113030D1 (en) 2007-10-31
CA2396722A1 (en) 2001-07-19
DK1246611T3 (en) 2008-01-28
US8021688B2 (en) 2011-09-20
WO2001051025A2 (en) 2001-07-19
ATE373470T1 (en) 2007-10-15
EP1246611A2 (en) 2002-10-09
WO2001051025A3 (en) 2002-04-18
ES2293982T3 (en) 2008-04-01

Similar Documents

Publication Publication Date Title
PT1073470E (en) Pharmaceutical compositions containing active compounds capable of improving the absorption of active ingredients
CA2420874A1 (en) Active ingredient combinations with insecticidal and acaricidal properties
CA2259780A1 (en) Alcohol based anti-microbial compositions with cosmetic appearance
DE69307977D1 (en) Stabilized derivatives of pharmaceutical compositions containing vitamin D2 and D3
WO1999039694A3 (en) Compositions containing organic compounds
EP1432408B8 (en) Pharmaceutical compositions comprising colloidal silicon dioxide
CA2338684A1 (en) Injectable propofol formulations
EP1059333A4 (en) Aqueous polytetrafluoroethylene dispersion composition
WO2002017870A3 (en) Clear antiperspirants and deodorants made with siloxane-based polyamides
CA2407621A1 (en) High efficacy, low residue antiperspirant stick compositions
AU2001289438A1 (en) Pharmaceutical semi-solid composition of isotretinoin
CO4890854A1 (en) NON-AQUEOUS PROTIC PEPTIDE FORMULATIONS
EP0882450A3 (en) Cholesterol-lowering composition comprising coenzyme Q
WO2001072125A8 (en) Active substance combinations having insecticidal and acaricidal properties
AU2001242328A1 (en) Formulations of active components in the form of a solid dispersion
WO2002047657A3 (en) Composition containing heteropolymers and oil-soluble polymers
NZ511085A (en) Oral pharmaceutical compositions containing buprenorphin
CA2022177A1 (en) Arginine deiminase, its manufacturing method, and an anti-cancer agent containing this enzyme as an effective ingredient
WO2001078682A3 (en) Sustained release drug compositions
AU2001267560A1 (en) Antistatic polyoxymethylene molding compounds
WO1998009608A3 (en) Personal care compositions
HUP0000818A2 (en) Aqueous compositions and their use
IL148193A0 (en) Hard candy with improved storage stability
WO2003020265A3 (en) Compositions comprising pectin and ascorbic acid
WO2003065803A3 (en) Use of a solvent/antifoam substance mixture in aqueous formulations and resulting formulations