AU2001241291A1 - 3-oxy-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadazine-1,1-dioxi e derivatives having diuretic and/or natriuretic activity - Google Patents

3-oxy-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadazine-1,1-dioxi e derivatives having diuretic and/or natriuretic activity

Info

Publication number
AU2001241291A1
AU2001241291A1 AU2001241291A AU4129101A AU2001241291A1 AU 2001241291 A1 AU2001241291 A1 AU 2001241291A1 AU 2001241291 A AU2001241291 A AU 2001241291A AU 4129101 A AU4129101 A AU 4129101A AU 2001241291 A1 AU2001241291 A1 AU 2001241291A1
Authority
AU
Australia
Prior art keywords
benzothiadazine
dioxi
sulfamyl
diuretic
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001241291A
Inventor
Petrus Johannes Maria Guelen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Farma Invent Bv
Original Assignee
FARMA INVENT BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FARMA INVENT BV filed Critical FARMA INVENT BV
Publication of AU2001241291A1 publication Critical patent/AU2001241291A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
    • C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
    • C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
    • C07D285/26—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom substituted in position 6 or 7 by sulfamoyl or substituted sulfamoyl radicals
    • C07D285/32—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom substituted in position 6 or 7 by sulfamoyl or substituted sulfamoyl radicals with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/80—Oxygen atoms
AU2001241291A 2000-03-08 2001-03-08 3-oxy-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadazine-1,1-dioxi e derivatives having diuretic and/or natriuretic activity Abandoned AU2001241291A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00200825 2000-03-08
EP00200825A EP1132382A1 (en) 2000-03-08 2000-03-08 3-Oxy-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadazine-1,1-dioxide derivatives having diuretic and/or natriuretic activity
PCT/NL2001/000191 WO2001070709A2 (en) 2000-03-08 2001-03-08 3-oxy-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadazine-1,1-dioxide derivatives having diuretic and/or natriuretic activity

Publications (1)

Publication Number Publication Date
AU2001241291A1 true AU2001241291A1 (en) 2001-10-03

Family

ID=8171166

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001241291A Abandoned AU2001241291A1 (en) 2000-03-08 2001-03-08 3-oxy-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadazine-1,1-dioxi e derivatives having diuretic and/or natriuretic activity

Country Status (5)

Country Link
EP (1) EP1132382A1 (en)
JP (1) JP2003528089A (en)
AU (1) AU2001241291A1 (en)
CA (1) CA2402572A1 (en)
WO (1) WO2001070709A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004270162B2 (en) 2003-08-28 2010-05-13 Nicox S.A. Nitrosated ad nitrosylated diuretic compouds, compositions and methods of use
US7396829B2 (en) 2005-02-24 2008-07-08 Nitromed, Inc. Nitric oxide enhancing diuretic compounds, compositions and methods of use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2886566A (en) * 1959-05-12 Sulfamyl-j
US3025292A (en) * 1962-03-13 Reduction of i
US3458513A (en) * 1967-11-02 1969-07-29 Wallace & Tiernan Inc 2-substituted-tetrahydro-halosulfamyl-quinazolinones

Also Published As

Publication number Publication date
WO2001070709A2 (en) 2001-09-27
WO2001070709A3 (en) 2002-01-10
EP1132382A1 (en) 2001-09-12
JP2003528089A (en) 2003-09-24
CA2402572A1 (en) 2001-09-27

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