AU2001239262A1 - Haemophilus influenza outer membrane protein and use thereof in vaccination - Google Patents

Haemophilus influenza outer membrane protein and use thereof in vaccination

Info

Publication number
AU2001239262A1
AU2001239262A1 AU2001239262A AU3926201A AU2001239262A1 AU 2001239262 A1 AU2001239262 A1 AU 2001239262A1 AU 2001239262 A AU2001239262 A AU 2001239262A AU 3926201 A AU3926201 A AU 3926201A AU 2001239262 A1 AU2001239262 A1 AU 2001239262A1
Authority
AU
Australia
Prior art keywords
outer membrane
vaccination
membrane protein
haemophilus influenza
influenza outer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001239262A
Inventor
Francois-Xavier Jacques Berthet
Philippe Denoel
Jan Poolman
Joelle Thonnard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Original Assignee
SmithKline Beecham Biologicals SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Biologicals SA filed Critical SmithKline Beecham Biologicals SA
Publication of AU2001239262A1 publication Critical patent/AU2001239262A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

This invention relates to recombinant bacterial outer membrane proteins comprising one or more LB1(f) peptides from surface-exposed loop 3 of MOMP P5 of non-typeable H. influenzae. Polynucleotides encoding these recombinant proteins are also covered. The invention also relates to a method of isolating the recombinant proteins and a vaccine composition for use in the treatment of Haemophilus influenzae infection.
AU2001239262A 2000-02-15 2001-02-13 Haemophilus influenza outer membrane protein and use thereof in vaccination Abandoned AU2001239262A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0003502.2A GB0003502D0 (en) 2000-02-15 2000-02-15 Vaccine
GB0003502 2000-02-15
PCT/EP2001/001556 WO2001061013A1 (en) 2000-02-15 2001-02-13 Haemophilus influenza outer membrane protein and use thereof in vaccination

Publications (1)

Publication Number Publication Date
AU2001239262A1 true AU2001239262A1 (en) 2001-08-27

Family

ID=9885665

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001239262A Abandoned AU2001239262A1 (en) 2000-02-15 2001-02-13 Haemophilus influenza outer membrane protein and use thereof in vaccination

Country Status (10)

Country Link
US (3) US20030096370A1 (en)
EP (1) EP1254234B1 (en)
JP (1) JP4815090B2 (en)
AT (1) ATE329032T1 (en)
AU (1) AU2001239262A1 (en)
CA (1) CA2399480C (en)
DE (1) DE60120357T2 (en)
ES (1) ES2264438T3 (en)
GB (1) GB0003502D0 (en)
WO (1) WO2001061013A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9812613D0 (en) * 1998-06-11 1998-08-12 Smithkline Beecham Biolog Vaccine
ES2537274T3 (en) 2005-08-10 2015-06-05 Arne Forsgren Ab Interaction of Moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system
BRPI0707154B8 (en) 2006-01-17 2022-12-20 Forsgren Arne vaccine composition
US8617574B2 (en) 2009-02-13 2013-12-31 Valneva Austria Gmbh Nontypable Haemophilus influenzae antigens

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9812613D0 (en) * 1998-06-11 1998-08-12 Smithkline Beecham Biolog Vaccine

Also Published As

Publication number Publication date
US7811590B2 (en) 2010-10-12
JP2003522543A (en) 2003-07-29
GB0003502D0 (en) 2000-04-05
ES2264438T3 (en) 2007-01-01
CA2399480A1 (en) 2001-08-23
US20030096370A1 (en) 2003-05-22
DE60120357D1 (en) 2006-07-20
EP1254234A1 (en) 2002-11-06
DE60120357T2 (en) 2007-06-06
US20090175912A1 (en) 2009-07-09
EP1254234B1 (en) 2006-06-07
CA2399480C (en) 2011-11-15
US20060251671A1 (en) 2006-11-09
ATE329032T1 (en) 2006-06-15
WO2001061013A1 (en) 2001-08-23
JP4815090B2 (en) 2011-11-16

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