AU2001238470A1 - 9-alkylamino-1-nitroacridine derivatives - Google Patents

9-alkylamino-1-nitroacridine derivatives

Info

Publication number
AU2001238470A1
AU2001238470A1 AU2001238470A AU3847001A AU2001238470A1 AU 2001238470 A1 AU2001238470 A1 AU 2001238470A1 AU 2001238470 A AU2001238470 A AU 2001238470A AU 3847001 A AU3847001 A AU 3847001A AU 2001238470 A1 AU2001238470 A1 AU 2001238470A1
Authority
AU
Australia
Prior art keywords
alkylamino
derivatives
nitroacridine
nitroacridine derivatives
alkoxyalkylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001238470A
Inventor
Jerzy Kazimierz Konopa
Raj Tiwari
Barbara Wysocka-Skrzela
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New York Medical College
Original Assignee
New York Medical College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Medical College filed Critical New York Medical College
Publication of AU2001238470A1 publication Critical patent/AU2001238470A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/06—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C07D219/12—Amino-alkylamino radicals attached in position 9

Abstract

The invention is directed to novel 9-hydroxyalkylamino-, 9-alkoxyalkylamino-1-nitroacridine derivatives. Methods of preparation, pharmaceutical compositions comprising said derivatives and their medical use are also encompassed by this invention.
AU2001238470A 2000-02-18 2001-02-16 9-alkylamino-1-nitroacridine derivatives Abandoned AU2001238470A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18353000P 2000-02-18 2000-02-18
US60183530 2000-02-18
PCT/US2001/005199 WO2001060801A2 (en) 2000-02-18 2001-02-16 9-alkylamino-1-nitroacridine derivatives

Publications (1)

Publication Number Publication Date
AU2001238470A1 true AU2001238470A1 (en) 2001-08-27

Family

ID=22673194

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001238470A Abandoned AU2001238470A1 (en) 2000-02-18 2001-02-16 9-alkylamino-1-nitroacridine derivatives

Country Status (12)

Country Link
EP (1) EP1257538B1 (en)
AT (1) ATE480522T1 (en)
AU (1) AU2001238470A1 (en)
CA (1) CA2400394C (en)
CY (1) CY1111290T1 (en)
DE (1) DE60143020D1 (en)
DK (1) DK1257538T3 (en)
ES (1) ES2351956T3 (en)
IL (1) IL150979A0 (en)
MX (1) MXPA02008012A (en)
PT (1) PT1257538E (en)
WO (1) WO2001060801A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011156889A1 (en) * 2010-06-14 2011-12-22 Trt Pharma Inc. Novel modulators of nrf2 and uses thereof
CN104326979B (en) * 2014-09-30 2015-12-30 广西中医药大学 2-methyl-9-acridine (to methoxy benzamide base) thiocarbamide and its production and use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL106752B1 (en) * 1976-02-25 1980-01-31 Politechnika Gdanska HOW TO RECEIVE NEW 1-NITRO-9-ALKYL-ALKYL-ALKYL-ACID AND OR THEIR SALT
PL101032B1 (en) * 1976-04-06 1978-11-30 METHOD OF OBTAINING 1-NITRO-9-DUALKYL-AMINOIZOALKYLAMIROACRIDINES OR THEIR SALTS
PL126407B1 (en) * 1980-04-23 1983-07-30 Politechnika Gdanska Process for preparing 1-nitro-9-hydroxyalkylaminoacridines or their salts

Also Published As

Publication number Publication date
CY1111290T1 (en) 2015-08-05
DE60143020D1 (en) 2010-10-21
DK1257538T3 (en) 2010-12-20
WO2001060801A3 (en) 2002-03-14
EP1257538B1 (en) 2010-09-08
ES2351956T3 (en) 2011-02-14
ATE480522T1 (en) 2010-09-15
WO2001060801A2 (en) 2001-08-23
MXPA02008012A (en) 2004-09-10
IL150979A0 (en) 2003-02-12
CA2400394C (en) 2011-05-03
PT1257538E (en) 2010-12-07
CA2400394A1 (en) 2001-08-23
EP1257538A2 (en) 2002-11-20

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