AU2001231090A1 - Magnetic resonance imaging using contrast agents bioactivated by enzymatic cleavage - Google Patents

Magnetic resonance imaging using contrast agents bioactivated by enzymatic cleavage

Info

Publication number
AU2001231090A1
AU2001231090A1 AU2001231090A AU3109001A AU2001231090A1 AU 2001231090 A1 AU2001231090 A1 AU 2001231090A1 AU 2001231090 A AU2001231090 A AU 2001231090A AU 3109001 A AU3109001 A AU 3109001A AU 2001231090 A1 AU2001231090 A1 AU 2001231090A1
Authority
AU
Australia
Prior art keywords
bioactivated
magnetic resonance
resonance imaging
contrast agents
enzymatic cleavage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001231090A
Other languages
English (en)
Inventor
Andrew Kolodziej
Thomas J. Mcmurray
Aleksandr Nivorozhkin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Epix Pharmaceuticals Inc
Original Assignee
Epix Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epix Pharmaceuticals Inc filed Critical Epix Pharmaceuticals Inc
Publication of AU2001231090A1 publication Critical patent/AU2001231090A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A61K49/143—Peptides, e.g. proteins the protein being an albumin, e.g. HSA, BSA, ovalbumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2001231090A 2000-01-22 2001-01-22 Magnetic resonance imaging using contrast agents bioactivated by enzymatic cleavage Abandoned AU2001231090A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17758000P 2000-01-22 2000-01-22
US60177580 2000-01-22
PCT/US2001/002221 WO2001052906A2 (en) 2000-01-22 2001-01-22 Magnetic resonance imaging using contrast agents prodrugs bioactivated by enzymatic cleavage

Publications (1)

Publication Number Publication Date
AU2001231090A1 true AU2001231090A1 (en) 2001-07-31

Family

ID=22649156

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001231090A Abandoned AU2001231090A1 (en) 2000-01-22 2001-01-22 Magnetic resonance imaging using contrast agents bioactivated by enzymatic cleavage

Country Status (4)

Country Link
EP (1) EP1251876A2 (ja)
JP (1) JP2003520255A (ja)
AU (1) AU2001231090A1 (ja)
WO (1) WO2001052906A2 (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6713045B1 (en) 1995-06-02 2004-03-30 Research Corporation Technologies, Inc. Targeted magnetic resonance imaging agents for the detection of physiological processes
CA2309749A1 (en) 1997-11-17 1999-05-27 Research Corporation Technologies, Inc. Magnetic resonance imaging agents for the detection of physiological agents
US6673333B1 (en) 2000-05-04 2004-01-06 Research Corporation Technologies, Inc. Functional MRI agents for cancer imaging
WO2002006287A2 (en) 2000-07-17 2002-01-24 California Institute Of Technology Macrocyclic mri contrast agents
TWI240632B (en) * 2001-07-30 2005-10-01 Epix Medical Inc Purified peptides for peptide-based multimeric targeted contrast agents
EP1539249B1 (en) * 2002-07-22 2008-07-09 Bracco Imaging S.p.A. Procedures of cellular labelling with paramagnetic complexes for mri applications
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
CA3044877A1 (en) 2016-11-28 2018-05-31 Bayer Pharma Aktiengesellschaft High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging
BR112021007707A2 (pt) 2018-11-23 2021-07-27 Bayer Aktiengesellschaft formulação de meios de contraste e processo de preparação da mesma

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3167679D1 (en) * 1980-03-31 1985-01-24 Inst Int Pathologie Cellulaire Pharmaceutical forms, their preparation and compositions containing the same
US5707605A (en) * 1995-06-02 1998-01-13 Research Corporation Technologies Magnetic resonance imaging agents for the detection of physiological agents
US5935824A (en) * 1996-01-31 1999-08-10 Technologene, Inc. Protein expression system
AU726914B2 (en) * 1996-04-01 2000-11-23 Epix Pharmaceuticals, Inc. Bioactivated diagnostic imaging contrast agents
HUP0101245A3 (en) * 1997-10-02 2003-10-28 Epix Pharmaceuticals Inc Cambr Contrast-enhanced diagnostic imaging method for monitoring interventional therapies
AU750686B2 (en) * 1997-10-27 2002-07-25 Research Corporation Technologies, Inc. Magnetic resonance imaging agents for the delivery of therapeutic agents
CA2309749A1 (en) * 1997-11-17 1999-05-27 Research Corporation Technologies, Inc. Magnetic resonance imaging agents for the detection of physiological agents

Also Published As

Publication number Publication date
WO2001052906A2 (en) 2001-07-26
EP1251876A2 (en) 2002-10-30
JP2003520255A (ja) 2003-07-02
WO2001052906A3 (en) 2002-01-24

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