AU2001229478A1 - Glutamine prevention of delayed-onset irinotecan-induced diarrhea - Google Patents

Glutamine prevention of delayed-onset irinotecan-induced diarrhea

Info

Publication number
AU2001229478A1
AU2001229478A1 AU2001229478A AU2947801A AU2001229478A1 AU 2001229478 A1 AU2001229478 A1 AU 2001229478A1 AU 2001229478 A AU2001229478 A AU 2001229478A AU 2947801 A AU2947801 A AU 2947801A AU 2001229478 A1 AU2001229478 A1 AU 2001229478A1
Authority
AU
Australia
Prior art keywords
irinotecan
glutamine
onset
delayed
prevention
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001229478A
Inventor
Diane Savarese
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Massachusetts UMass
Original Assignee
University of Massachusetts UMass
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Massachusetts UMass filed Critical University of Massachusetts UMass
Publication of AU2001229478A1 publication Critical patent/AU2001229478A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2001229478A 2000-01-18 2001-01-12 Glutamine prevention of delayed-onset irinotecan-induced diarrhea Abandoned AU2001229478A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48496200A 2000-01-18 2000-01-18
US09484962 2000-01-18
PCT/US2001/001270 WO2001052828A2 (en) 2000-01-18 2001-01-12 Glutamine prevention of delayed-onset irinotecan-induced diarrhea

Publications (1)

Publication Number Publication Date
AU2001229478A1 true AU2001229478A1 (en) 2001-07-31

Family

ID=23926357

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001229478A Abandoned AU2001229478A1 (en) 2000-01-18 2001-01-12 Glutamine prevention of delayed-onset irinotecan-induced diarrhea

Country Status (4)

Country Link
AU (1) AU2001229478A1 (en)
CO (1) CO5280204A1 (en)
PE (1) PE20011042A1 (en)
WO (1) WO2001052828A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2295429A1 (en) * 2000-01-06 2001-07-06 Michael Michael Treatment or prevention of diarrhea
WO2004103371A1 (en) * 2003-05-21 2004-12-02 Pharmacia & Upjohn Company Llc Use of cftr inhibitors for the treatment of chemotherapy-induced diarrhea

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786344A (en) * 1994-07-05 1998-07-28 Arch Development Corporation Camptothecin drug combinations and methods with reduced side effects
US5646159A (en) * 1994-07-20 1997-07-08 Research Triangle Institute Water-soluble esters of camptothecin compounds

Also Published As

Publication number Publication date
WO2001052828A2 (en) 2001-07-26
PE20011042A1 (en) 2001-09-26
WO2001052828A3 (en) 2002-04-18
CO5280204A1 (en) 2003-05-30

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