AU2001229406A1 - Transverse thermal modulation - Google Patents

Transverse thermal modulation

Info

Publication number
AU2001229406A1
AU2001229406A1 AU2001229406A AU2940601A AU2001229406A1 AU 2001229406 A1 AU2001229406 A1 AU 2001229406A1 AU 2001229406 A AU2001229406 A AU 2001229406A AU 2940601 A AU2940601 A AU 2940601A AU 2001229406 A1 AU2001229406 A1 AU 2001229406A1
Authority
AU
Australia
Prior art keywords
tubular member
gas stream
temperature
source
thermal modulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001229406A
Inventor
Chris A. Billesbach
Edward B. Ledford
Joel R. Termaat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zoex Corp
Original Assignee
Zoex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoex Corp filed Critical Zoex Corp
Publication of AU2001229406A1 publication Critical patent/AU2001229406A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • G01N30/463—Flow patterns using more than one column with serial coupling of separation columns for multidimensional chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/30—Control of physical parameters of the fluid carrier of temperature
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • G01N30/465—Flow patterns using more than one column with serial coupling of separation columns with specially adapted interfaces between the columns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/30—Control of physical parameters of the fluid carrier of temperature
    • G01N2030/3023—Control of physical parameters of the fluid carrier of temperature using cryogenic fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N2030/621—Detectors specially adapted therefor signal-to-noise ratio
    • G01N2030/623—Detectors specially adapted therefor signal-to-noise ratio by modulation of sample feed or detector response
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns

Landscapes

  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Magnetic Heads (AREA)

Abstract

A method of thermally modulating a tubular member carrying a sample substance therethrough is provided. The method includes the steps of (a) directing at least one gas stream toward a tubular member in a direction substantially transverse to the tubular member, wherein the temperature of the gas stream differs from the temperature of the tubular member; and (b) varying the gas flow rate of the at least one gas stream as a function of time to thermally modulate the tubular member. An apparatus is also provided for thermal modulation and includes: a tubular member for carrying a sample substance therethrough in a fluid medium; a gas stream source for directing a gas stream toward the tubular member in a direction substantially transverse to the tubular member; a gas stream supplied from the source with a temperature that differs from the temperature of the tubular member; and a gas stream of varying gas flow rate supplied from the gas stream source as a function of time to thermally modulate the tubular member.
AU2001229406A 2000-01-12 2001-01-12 Transverse thermal modulation Abandoned AU2001229406A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17572700P 2000-01-12 2000-01-12
US60175727 2000-01-12
PCT/US2001/001065 WO2001051179A1 (en) 2000-01-12 2001-01-12 Transverse thermal modulation

Publications (1)

Publication Number Publication Date
AU2001229406A1 true AU2001229406A1 (en) 2001-07-24

Family

ID=22641388

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001229406A Abandoned AU2001229406A1 (en) 2000-01-12 2001-01-12 Transverse thermal modulation

Country Status (6)

Country Link
US (1) US6547852B2 (en)
EP (1) EP1251939B1 (en)
AT (1) ATE514474T1 (en)
AU (1) AU2001229406A1 (en)
ES (1) ES2369636T3 (en)
WO (1) WO2001051179A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002039106A1 (en) * 2000-12-19 2002-05-16 Thermo Finnigan Italia S.P.A. Modulator for gas chromatography
WO2003067250A1 (en) * 2002-02-04 2003-08-14 Thermo Finnigan Italia S.P.A. Method and device for comprehensive two-dimensional gas chromatography
ITMI20020549A1 (en) * 2002-03-15 2003-09-15 Thermo Finnigan Italia S P A CRYOGENIC MODULATOR FOR GAS CHROMATOGRAPHY
JP4231793B2 (en) * 2002-03-19 2009-03-04 ゾイクス コーポレーション Method and apparatus for measuring the speed of a chromatographic pulse
US7091044B2 (en) * 2003-08-29 2006-08-15 Valco Instruments Co., Inc. Partial modulation via pulsed flow modulator for comprehensive two-dimensional liquid or gas chromatography
ATE369557T1 (en) * 2005-02-25 2007-08-15 Max Planck Gesellschaft GAS CHROMATOGRAPHY APPARATUS
DE102005050114A1 (en) * 2005-10-18 2007-04-19 Studiengesellschaft Kohle Mbh Analysis of mixtures
US20070137481A1 (en) * 2005-12-20 2007-06-21 Jan Blomberg Method to measure olefins in a complex hydrocarbon mixture
EP2118645A1 (en) * 2007-03-07 2009-11-18 Shell Internationale Research Maatschappij B.V. Method of analysing the hydrocarbon compounds in a bituminous material
EP2302372A1 (en) * 2009-09-18 2011-03-30 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH Method and device for repetitive chemical analysis of a gas flow
US8607615B2 (en) * 2009-10-19 2013-12-17 The Regents Of The University Of Michigan Microfabricated thermal modulator for comprehensive 2D gas chromatography
US8277544B2 (en) * 2010-03-26 2012-10-02 Agilent Technologies, Inc. Thermal modulation device for two dimensional gas chromatography
US8974580B2 (en) * 2012-01-09 2015-03-10 Exxonmobil Research And Engineering Company Modification of cold jet nozzle in a jet modulator design for comprehensive two-dimensional gas chromatography
JP6654000B2 (en) * 2015-05-19 2020-02-26 株式会社日立ハイテクノロジーズ Sample fragmentation equipment
EP3436811A4 (en) * 2016-04-01 2019-11-27 Leco Corporation Thermal modulator
CN106940352B (en) * 2017-04-21 2018-12-18 中国地质大学（武汉） A kind of comprehensive two dimensional gas chromatography modulator based on semiconductor heating and Refrigeration Technique

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3057183A (en) 1958-08-22 1962-10-09 Phillips Petroleum Co Chromatographic analyzer
US3043127A (en) 1958-12-11 1962-07-10 Phillips Petroleum Co Thermochromatography heater
US3309504A (en) * 1964-08-24 1967-03-14 Combustion Eng System for heating chromatographic columns
US3305000A (en) * 1965-02-08 1967-02-21 Barber Colman Co Temperature control system for chromatographs
IT1134198B (en) 1980-11-06 1986-07-31 Erba Strumentazione DEVICE FOR VAPORIZATION INJECTION IN A GAS CHROMATOGRAPHIC COLUMN
US4923486A (en) * 1988-12-22 1990-05-08 University Of Dayton Gas chromatography methods and apparatus
US4948389A (en) * 1989-05-22 1990-08-14 Hewlett-Packard Company Gas chromatograph having cyro blast coolings
EP0459677A3 (en) 1990-05-29 1993-02-03 Thermedics, Inc. Selective, high speed detection of vapors with analysis of multiple gc-separated portions
US5135549A (en) 1991-01-30 1992-08-04 The Board Of Trustees Of Southern Illinois University Chromatographic technique and apparatus
US5196039A (en) 1991-01-30 1993-03-23 Southern Illinois University At Carbondale Apparatus and method of multi-dimensional chemical separation
US5215556A (en) * 1992-04-15 1993-06-01 The Dow Chemical Company Apparatus and method for establishing a temperature gradient in a chromatography column
US5547497A (en) * 1992-09-30 1996-08-20 Chromatofast, Inc. Apparatus for gas chromatography
DE9216438U1 (en) 1992-12-03 1993-01-14 Hammelmann, Paul, 4740 Oelde Nozzle head for a rotary spray device
US5341578A (en) * 1993-04-30 1994-08-30 J. A. Horn Blower dryer pulsed airflow generating mechanism
AU2781995A (en) * 1994-06-24 1996-01-19 Universite De Montreal Selective removal of volatile substances injected into a chromatographic packing filled column
US6007602A (en) 1995-10-13 1999-12-28 Board Of Trustees Of Southern Illinois University On Behalf Of Southern Illinois University At Carbondale Apparatus and method for chemical modulation
US5596876A (en) * 1995-11-28 1997-01-28 Scientific Instrument Services, Inc. Miniaturized cryogenic trap apparatus
JP3290968B2 (en) * 1998-04-30 2002-06-10 フロンティア・ラボ株式会社 Sample concentrator

Also Published As

Publication number Publication date
US6547852B2 (en) 2003-04-15
EP1251939A1 (en) 2002-10-30
ATE514474T1 (en) 2011-07-15
ES2369636T3 (en) 2011-12-02
EP1251939A4 (en) 2004-12-29
EP1251939B1 (en) 2011-06-29
WO2001051179A1 (en) 2001-07-19
US20010037727A1 (en) 2001-11-08

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