AU2000274809A1 - Inhibition of stenosis or restenosis by p-selectin antagonists - Google Patents

Inhibition of stenosis or restenosis by p-selectin antagonists

Info

Publication number
AU2000274809A1
AU2000274809A1 AU2000274809A AU7480900A AU2000274809A1 AU 2000274809 A1 AU2000274809 A1 AU 2000274809A1 AU 2000274809 A AU2000274809 A AU 2000274809A AU 7480900 A AU7480900 A AU 7480900A AU 2000274809 A1 AU2000274809 A1 AU 2000274809A1
Authority
AU
Australia
Prior art keywords
stenosis
restenosis
inhibition
selectin antagonists
selectin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2000274809A
Inventor
Anjali Kumar
Yahye Merhi
Robert G. Schuab
Jean-Francois Tanguay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut de Cardiologie de Montreal
Genetics Institute LLC
Original Assignee
Institut de Cardiologie de Montreal
Genetics Institute LLC
Montreal Heart Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut de Cardiologie de Montreal, Genetics Institute LLC, Montreal Heart Inst filed Critical Institut de Cardiologie de Montreal
Publication of AU2000274809A1 publication Critical patent/AU2000274809A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056—Lectin superfamily, e.g. CD23, CD72
    • C07K14/70564—Selectins, e.g. CD62
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
AU2000274809A 2000-09-12 2000-09-12 Inhibition of stenosis or restenosis by p-selectin antagonists Abandoned AU2000274809A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/025007 WO2002022820A1 (en) 2000-09-12 2000-09-12 Inhibition of stenosis or restenosis by p-selectin antagonists

Publications (1)

Publication Number Publication Date
AU2000274809A1 true AU2000274809A1 (en) 2002-03-26

Family

ID=21741767

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2000274809A Abandoned AU2000274809A1 (en) 2000-09-12 2000-09-12 Inhibition of stenosis or restenosis by p-selectin antagonists

Country Status (3)

Country Link
EP (1) EP1325123A4 (en)
AU (1) AU2000274809A1 (en)
WO (1) WO2002022820A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY28886A1 (en) 2004-05-10 2005-12-30 Boehringer Ingelheim Int ANTIBODIES CONSISTING IN POLYPEPTIDES AND DERIVATIVES UNDERSTANDING THREE SEQUENCES CONCERNING THE FOLLOWING NUMBERS OF SEQ. ID: 1-3 AND 4-6; 7-9 AND 10-12 AND 13-15 OR 16-18
EP1751300B1 (en) 2004-05-11 2017-11-08 AbGenomics Coöperatief U.A. T-cell death-inducing epitopes
PL2264043T3 (en) 2005-09-02 2018-04-30 Glycomimetics, Inc. Heterobifunctional pan-selectin inhibitors
WO2009126556A1 (en) 2008-04-08 2009-10-15 Glycomimetics, Inc. Pan-selectin inhibitor with enhanced pharmacokinetic activity
WO2012037034A1 (en) 2010-09-14 2012-03-22 Glycomimetics, Inc. E-selectin antagonists
WO2012174001A1 (en) 2011-06-13 2012-12-20 Abgenomics Cooperatief U.A. Anti-psgl-1 antibodies and uses thereof
PL2794626T6 (en) 2011-12-22 2020-11-02 Glycomimetics, Inc. E-selectin antagonist compounds
PL2928476T3 (en) 2012-12-07 2018-07-31 Glycomimetics, Inc. Compounds, compositions and methods using e-selectin antagonists for mobilization of hematopoietic cells
AU2015355136B2 (en) 2014-12-03 2020-06-25 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectins and CXCR4 chemokine receptors
CA3009836A1 (en) 2016-01-22 2017-07-27 Glycomimetics, Inc. Glycomimetic inhibitors of pa-il and pa-iil lectins
US11291678B2 (en) 2016-03-02 2022-04-05 Glycomimetics, Inc Methods for the treatment and/or prevention of cardiovascular disease by inhibition of E-selectin
WO2018031445A1 (en) 2016-08-08 2018-02-15 Glycomimetics, Inc. Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4
BR112019006642A2 (en) 2016-10-07 2019-07-02 Glycomimetics Inc highly potent multimeric e-selectin antagonists
JP7272956B2 (en) 2017-03-15 2023-05-12 グリコミメティクス， インコーポレイテッド Galactopyranosyl-cyclohexyl derivatives as E-selectin antagonists
JP7275131B2 (en) 2017-11-30 2023-05-17 グリコミメティクス， インコーポレイテッド Methods of mobilizing bone marrow-infiltrating lymphocytes and uses thereof
JP7304863B2 (en) 2017-12-29 2023-07-07 グリコミメティクス， インコーポレイテッド Heterobifunctional inhibitors of E-selectin and galectin-3
JP7455064B2 (en) 2018-03-05 2024-03-25 グリコミメティクス， インコーポレイテッド Methods of treating acute myeloid leukemia and related conditions
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1396542T3 (en) * 1992-10-23 2011-06-06 Genetics Inst Llc P-selectin ligand protein
WO1995030001A2 (en) * 1994-04-28 1995-11-09 Genetics Institute, Inc. Novel p-selectin ligand protein
CA2191577C (en) * 1994-06-03 2010-03-16 Denisa D. Wagner Method for treating and preventing atherosclerosis
EP0850243B1 (en) * 1995-08-03 2003-10-08 Board Of Regents Of The University Of Oklahoma o-glycan inhibitors of selectin mediated inflammation
WO1999043834A2 (en) * 1998-02-27 1999-09-02 Genetics Institute, Inc. P-selectin ligand protein, including tetrameric fusion proteins
US6593459B1 (en) * 1998-06-16 2003-07-15 The Board Of Regents Of The University Of Oklahoma Synthetic glycosulfopeptides and methods of synthesis thereof
EP1518931A1 (en) * 2000-03-31 2005-03-30 Genetics Institute, LLC Use of P-selectin glycoprotein ligand-1 (PSGL-1) and fragments thereof for the inhibition of thrombosis

Also Published As

Publication number Publication date
EP1325123A4 (en) 2004-07-21
WO2002022820A1 (en) 2002-03-21
EP1325123A1 (en) 2003-07-09

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