AU2000263864A1 - Tissue specific prodrug - Google Patents
Tissue specific prodrugInfo
- Publication number
- AU2000263864A1 AU2000263864A1 AU2000263864A AU6386400A AU2000263864A1 AU 2000263864 A1 AU2000263864 A1 AU 2000263864A1 AU 2000263864 A AU2000263864 A AU 2000263864A AU 6386400 A AU6386400 A AU 6386400A AU 2000263864 A1 AU2000263864 A1 AU 2000263864A1
- Authority
- AU
- Australia
- Prior art keywords
- tissue specific
- specific prodrug
- prodrug
- tissue
- specific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/588,822 US6504014B1 (en) | 1997-05-19 | 2000-06-07 | Tissue specific prodrug |
US09588822 | 2000-06-07 | ||
PCT/US2000/020542 WO2001093861A1 (en) | 2000-06-07 | 2000-07-28 | Tissue specific prodrug |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2000263864A1 true AU2000263864A1 (en) | 2001-12-17 |
Family
ID=24355434
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2000263864A Abandoned AU2000263864A1 (en) | 2000-06-07 | 2000-07-28 | Tissue specific prodrug |
Country Status (3)
Country | Link |
---|---|
US (1) | US6504014B1 (en) |
AU (1) | AU2000263864A1 (en) |
WO (1) | WO2001093861A1 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7618789B2 (en) | 2001-04-06 | 2009-11-17 | The United States Of America As Represented By The Secretary Of Department Of Health And Human Services | Use of semenogelin in the diagnosis, prognosis and treatment of cancer |
WO2003000201A2 (en) * | 2001-06-25 | 2003-01-03 | Drug Innovation & Design, Incorporated | Exponential pattern recognition based cellular targeting, compositions, methods and anticancer applications |
WO2003018611A2 (en) * | 2001-08-24 | 2003-03-06 | University Of Victoria Innovation And Development Corporation | Proaerolysin containing protease activation sequences and methods of use for treatment of prostate cancer |
US20040001801A1 (en) * | 2002-05-23 | 2004-01-01 | Corvas International, Inc. | Conjugates activated by cell surface proteases and therapeutic uses thereof |
US8809504B2 (en) * | 2002-09-03 | 2014-08-19 | Vit Lauermann | Inhibitor which is deactivatable by a reagent produced by a target cell |
US7314872B2 (en) * | 2003-08-20 | 2008-01-01 | Irm Llc | Inhibitors of cathepsin S |
JP5220594B2 (en) | 2005-06-14 | 2013-06-26 | プロトクス セラピューティックス インコーポレイティッド | Method for treating or preventing benign prostatic hypertrophy using pore-forming modified proteins |
WO2010107909A2 (en) | 2009-03-17 | 2010-09-23 | The Johns Hopkins University | Methods and compositions for the detection of cancer |
EP2461813A4 (en) * | 2009-08-05 | 2014-02-19 | Univ Wake Forest Health Sciences | Compositions and methods for inducing apoptosis in prostate cancer cells |
WO2011072133A1 (en) | 2009-12-09 | 2011-06-16 | William Marsh Rice University | Therapeutic compositions and methods for delivery of active agents cleavably linked to nanoparticles |
US10441561B2 (en) | 2012-07-26 | 2019-10-15 | The William M. Yanbrough Foundation | Method for treating benign prostatic hyperplasia (BPH), prostatitis, and prostate cancer |
JP2016518339A (en) | 2013-03-15 | 2016-06-23 | ジェンスペラ,インコーポレイテッド | Method for making a cancer composition |
GEP20237497B (en) | 2013-10-18 | 2023-04-10 | Deutsches Krebsforsch | Labeled inhibitors of prostate specific membrane antigen (psma), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1124922A (en) | 1993-06-03 | 1996-06-19 | 悉尼大学 | Use of natural products and related synthetic compounds for the treatment of cardiovascular disease |
US5866679A (en) | 1994-06-28 | 1999-02-02 | Merck & Co., Inc. | Peptides |
US5599686A (en) | 1994-06-28 | 1997-02-04 | Merck & Co., Inc. | Peptides |
US6143864A (en) | 1994-06-28 | 2000-11-07 | Merck & Co., Inc. | Peptides |
US5905089A (en) * | 1997-04-14 | 1999-05-18 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Use of sesquiterpene lactones for treatment of severe inflammatory disorders |
AU740597B2 (en) | 1997-07-10 | 2001-11-08 | Merck & Co., Inc. | Conjugates useful in the treatment of prostate cancer |
-
2000
- 2000-06-07 US US09/588,822 patent/US6504014B1/en not_active Expired - Lifetime
- 2000-07-28 AU AU2000263864A patent/AU2000263864A1/en not_active Abandoned
- 2000-07-28 WO PCT/US2000/020542 patent/WO2001093861A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2001093861A1 (en) | 2001-12-13 |
US6504014B1 (en) | 2003-01-07 |
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