AU1564897A - Antisense inhibition of human adhesion molecules - Google Patents
Antisense inhibition of human adhesion moleculesInfo
- Publication number
- AU1564897A AU1564897A AU15648/97A AU1564897A AU1564897A AU 1564897 A AU1564897 A AU 1564897A AU 15648/97 A AU15648/97 A AU 15648/97A AU 1564897 A AU1564897 A AU 1564897A AU 1564897 A AU1564897 A AU 1564897A
- Authority
- AU
- Australia
- Prior art keywords
- adhesion molecules
- antisense inhibition
- human adhesion
- human
- antisense
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1996/019194 WO1998024797A1 (en) | 1996-12-02 | 1996-12-02 | Antisense inhibition of human adhesion molecules |
Publications (1)
Publication Number | Publication Date |
---|---|
AU1564897A true AU1564897A (en) | 1998-06-29 |
Family
ID=22256225
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU15648/97A Abandoned AU1564897A (en) | 1996-12-02 | 1996-12-02 | Antisense inhibition of human adhesion molecules |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0950060A4 (en) |
JP (1) | JP2001505432A (en) |
AU (1) | AU1564897A (en) |
CA (1) | CA2273203A1 (en) |
WO (1) | WO1998024797A1 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19844111A1 (en) * | 1998-09-25 | 2000-04-20 | Deutsches Krebsforsch | Novel antisense nucleic acids targeted to specific sequences within the ICAM-1 gene, useful for treating inflammation and metastasis |
AU6193699A (en) * | 1998-09-25 | 2000-04-17 | Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts | Antisense-sequences for inhibiting the expression of the adhesion molecule icam-1 |
US6114517A (en) * | 1998-12-10 | 2000-09-05 | Isis Pharmaceuticals Inc. | Methods of modulating tumor necrosis factor α-induced expression of cell adhesion molecules |
US6670321B1 (en) | 1998-12-30 | 2003-12-30 | The Children's Medical Center Corporation | Prevention and treatment for retinal ischemia and edema |
EP1146908B1 (en) * | 1999-01-27 | 2005-08-03 | Becker, David, Dr. | Formulations comprising antisense nucleotides to connexins |
DE10019252A1 (en) * | 2000-04-18 | 2001-10-31 | Klaus Karl Degitz | Polydeoxyribonucleotides to inhibit ICAM-1 gene expression |
DE10141443B4 (en) * | 2001-08-23 | 2007-02-01 | Christos C. Prof. Dr. Zouboulis | Use of molecular biologically produced, non-viral agents for the treatment of acne |
KR101350837B1 (en) | 2003-12-03 | 2014-01-14 | 코다 테라퓨틱스, 인크. | Antisense compounds targeted to connexins and methods of use thereof |
KR102073629B1 (en) | 2005-02-03 | 2020-02-05 | 코다 테라퓨틱스 (엔지) 리미티드 | Anti-connexin compounds and uses thereof |
KR20150072458A (en) | 2006-11-15 | 2015-06-29 | 코다 테라퓨틱스, 인크. | Improved methods and compositions for wound healing |
US8063023B2 (en) | 2006-12-11 | 2011-11-22 | Coda Therapeuctics, Inc. | Impaired wound healing compositions and treatments |
US8975237B2 (en) | 2007-12-21 | 2015-03-10 | Coda Therapeutics, Inc. | Treatment of fibrotic conditions |
EA201790434A1 (en) | 2014-08-22 | 2017-07-31 | Окленд Юнисервисиз Лимитед | CHANNEL MODULATORS |
WO2018199777A1 (en) | 2017-04-28 | 2018-11-01 | Auckland Uniservices Limited | Methods of treatment and novel constructs |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5284931A (en) * | 1987-05-04 | 1994-02-08 | Dana Farber Cancer Institute | Intercellular adhesion molecules, and their binding ligands |
US5591623A (en) * | 1990-08-14 | 1997-01-07 | Isis Pharmaceuticals, Inc. | Oligonucleotide modulation of cell adhesion |
JPH07501204A (en) * | 1991-06-28 | 1995-02-09 | マサチューセッツ インスティテュート オブ テクノロジー | Topical oligonucleotide therapy |
CA2082411A1 (en) * | 1991-06-28 | 1992-12-29 | Robert D. Rosenberg | Localized oligonucleotide therapy |
US5580969A (en) * | 1992-07-24 | 1996-12-03 | The United States Of America As Represented By The Secretary Of The Navy | Antisense oligonucleotides directed against human ICAM-I RNA |
EP0691853B1 (en) * | 1993-04-01 | 2002-06-05 | Isis Pharmaceuticals, Inc. | ANTISENSE OLIGOS WHICH INTERFERE WITH mRNA CAP ACTIVITY AND INHIBIT TRANSLATION |
WO1996015780A1 (en) * | 1994-11-23 | 1996-05-30 | Isis Pharmaceuticals, Inc. | Compositions and methods for preventing and treating allograft rejection |
-
1996
- 1996-12-02 JP JP52553398A patent/JP2001505432A/en not_active Ceased
- 1996-12-02 EP EP96945380A patent/EP0950060A4/en not_active Withdrawn
- 1996-12-02 WO PCT/US1996/019194 patent/WO1998024797A1/en not_active Application Discontinuation
- 1996-12-02 CA CA002273203A patent/CA2273203A1/en not_active Abandoned
- 1996-12-02 AU AU15648/97A patent/AU1564897A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2001505432A (en) | 2001-04-24 |
EP0950060A4 (en) | 2000-07-05 |
CA2273203A1 (en) | 1998-06-11 |
WO1998024797A1 (en) | 1998-06-11 |
EP0950060A1 (en) | 1999-10-20 |
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