AU1488797A - Pharmaceutical composition which comprises hirudin and process for preparing it - Google Patents

Pharmaceutical composition which comprises hirudin and process for preparing it

Info

Publication number
AU1488797A
AU1488797A AU14887/97A AU1488797A AU1488797A AU 1488797 A AU1488797 A AU 1488797A AU 14887/97 A AU14887/97 A AU 14887/97A AU 1488797 A AU1488797 A AU 1488797A AU 1488797 A AU1488797 A AU 1488797A
Authority
AU
Australia
Prior art keywords
preparing
pharmaceutical composition
hirudin
comprises hirudin
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU14887/97A
Inventor
Dieter Brazel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Publication of AU1488797A publication Critical patent/AU1488797A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A61K38/58—Protease inhibitors from animals; from humans from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AU14887/97A 1996-02-27 1997-02-25 Pharmaceutical composition which comprises hirudin and process for preparing it Abandoned AU1488797A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19607239 1996-02-27
DE19607239A DE19607239A1 (en) 1996-02-27 1996-02-27 Pharmaceutical composition containing hirudin and process for its preparation

Publications (1)

Publication Number Publication Date
AU1488797A true AU1488797A (en) 1997-09-04

Family

ID=7786508

Family Applications (1)

Application Number Title Priority Date Filing Date
AU14887/97A Abandoned AU1488797A (en) 1996-02-27 1997-02-25 Pharmaceutical composition which comprises hirudin and process for preparing it

Country Status (6)

Country Link
EP (1) EP0792648A3 (en)
JP (1) JPH09227407A (en)
KR (1) KR970061266A (en)
AU (1) AU1488797A (en)
CA (1) CA2198576A1 (en)
DE (1) DE19607239A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ336793A (en) * 1997-01-20 2000-08-25 Japan Energy Corp Method for stabilizing peptides by adding an organic acid and then lyophilizing the peptide mixture
JP4502352B2 (en) * 2001-06-29 2010-07-14 栄研化学株式会社 Heme protein stabilization method and storage solution
CN102150654A (en) * 2011-02-19 2011-08-17 蚌埠医学院附属医院 Additive composition for viscus function protection fluid

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3342139A1 (en) 1983-11-22 1985-05-30 Ciba-Geigy Ag, Basel DESULFATOHIRUDINE, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL AGENTS
CA1341414C (en) 1984-03-27 2002-12-31 Paul Tolstoshev Expression vectors of hirudine, transformed cells and process for the preparation of hirudine
DE3438296A1 (en) 1984-04-18 1985-11-07 Hoechst Ag, 6230 Frankfurt NEW POLYPEPTIDES WITH A BLOOD-CLOTHING EFFECT, METHOD FOR THE PRODUCTION OR THEIR RECOVERY, THEIR USE AND THE CONTAINERS THEREOF
DE3429430A1 (en) 1984-08-10 1986-02-20 Hoechst Ag, 6230 Frankfurt GENE TECHNOLOGICAL METHOD FOR PRODUCING HIRUDINE AND MEANS FOR IMPLEMENTING THIS METHOD
DE3445532A1 (en) 1984-12-13 1986-06-19 Plantorgan Werk Heinrich G.E. Christensen, KG, 2903 Bad Zwischenahn HIRUDIN-PA, DESULFATOHIRUDINE-PA, METHOD FOR PRODUCTION AND PHARMACEUTICAL AGENTS THAT CONTAIN THESE ACTIVE SUBSTANCES
EP0324712B1 (en) 1985-04-11 1993-04-07 Hoechst Aktiengesellschaft Hirudin derivative
DE3622642A1 (en) * 1986-07-05 1988-01-14 Behringwerke Ag ONE-COMPONENT TISSUE ADHESIVE AND METHOD FOR THE PRODUCTION THEREOF
CA2000887A1 (en) * 1988-11-01 1990-05-01 Cecilia S.L. Ku Thromboresistant materials and methods for making same
CA2064231A1 (en) * 1989-07-20 1991-01-21 John M. Maraganore Combinations and methods for treating or preventing thrombotic diseases
AU3606793A (en) * 1992-02-05 1993-09-03 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
GB9209032D0 (en) * 1992-04-25 1992-06-10 Ciba Geigy Ag New peptide derivatives
JPH07138298A (en) * 1993-11-19 1995-05-30 Japan Energy Corp Production of sulfate derivative of hirudin analog or its salt
GB9401448D0 (en) 1994-01-26 1994-03-23 Ciba Geigy Ag Stable dry powders
GB9401447D0 (en) 1994-01-26 1994-03-23 Ciba Geigy Ag Pharmaceutical compositions

Also Published As

Publication number Publication date
EP0792648A3 (en) 1999-01-07
CA2198576A1 (en) 1997-08-27
KR970061266A (en) 1997-09-12
JPH09227407A (en) 1997-09-02
EP0792648A2 (en) 1997-09-03
DE19607239A1 (en) 1997-08-28

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted