AU1410399A - Nucleic acid transfer vector for the introduction of nucleic acid into the dna of a cell - Google Patents

Nucleic acid transfer vector for the introduction of nucleic acid into the dna of a cell

Info

Publication number
AU1410399A
AU1410399A AU14103/99A AU1410399A AU1410399A AU 1410399 A AU1410399 A AU 1410399A AU 14103/99 A AU14103/99 A AU 14103/99A AU 1410399 A AU1410399 A AU 1410399A AU 1410399 A AU1410399 A AU 1410399A
Authority
AU
Australia
Prior art keywords
nucleic acid
dna
introduction
cell
transfer vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU14103/99A
Inventor
Karl J. Clark
Adam J. Dupuy
Stephen C. Ekker
Perry B. Hackett
Zoltan Ivics
Zsuzsanna Izsvak
David A. Largaespada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Minnesota
Original Assignee
University of Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Minnesota filed Critical University of Minnesota
Publication of AU1410399A publication Critical patent/AU1410399A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/60—Vectors containing traps for, e.g. exons, promoters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/90—Vectors containing a transposable element
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/005—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination repressible enhancer/promoter combination, e.g. KRAB
    • C12N2830/006—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination repressible enhancer/promoter combination, e.g. KRAB tet repressible
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU14103/99A 1997-11-13 1998-11-13 Nucleic acid transfer vector for the introduction of nucleic acid into the dna of a cell Abandoned AU1410399A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6530397P 1997-11-13 1997-11-13
US60065303 1997-11-13
PCT/US1998/024348 WO1999025817A2 (en) 1997-11-13 1998-11-13 Tc1-based transposon vectors

Publications (1)

Publication Number Publication Date
AU1410399A true AU1410399A (en) 1999-06-07

Family

ID=22061760

Family Applications (1)

Application Number Title Priority Date Filing Date
AU14103/99A Abandoned AU1410399A (en) 1997-11-13 1998-11-13 Nucleic acid transfer vector for the introduction of nucleic acid into the dna of a cell

Country Status (5)

Country Link
EP (1) EP1034258A2 (en)
JP (1) JP2001523450A (en)
AU (1) AU1410399A (en)
CA (1) CA2309000A1 (en)
WO (1) WO1999025817A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0973928T3 (en) 1997-03-11 2010-08-09 Univ Minnesota DNA-based transposon system for introducing nucleic acid into DNA in a cell
US7160682B2 (en) 1998-11-13 2007-01-09 Regents Of The University Of Minnesota Nucleic acid transfer vector for the introduction of nucleic acid into the DNA of a cell
WO2000068399A2 (en) * 1999-05-11 2000-11-16 Regents Of The University Of Minnesota Vector-mediated delivery of integrating transposon sequences
WO2001029205A2 (en) * 1999-10-19 2001-04-26 Minos Biosystems Limited Method for genetic manipulation
AU1100201A (en) 1999-10-28 2001-05-08 Board Of Trustees Of The Leland Stanford Junior University Methods of in vivo gene transfer using a sleeping beauty transposon system
WO2001055369A1 (en) 2000-01-28 2001-08-02 The Scripps Research Institute Synthetic internal ribosome entry sites and methods of identifying same
CA2407651C (en) * 2000-04-27 2013-07-02 Max-Delbruck-Centrum Fur Molekulare Medizin Sleeping beauty, a transposon vector with a broad host range for the genetic transformation in vertebrates
EP1286699A2 (en) * 2000-05-19 2003-03-05 Regents Of The University Of Minnesota Composition for delivery of compounds to cells
US8227432B2 (en) 2002-04-22 2012-07-24 Regents Of The University Of Minnesota Transposon system and methods of use
DE10224242A1 (en) * 2002-05-29 2003-12-11 Max Delbrueck Centrum Frog Prince, a transposon vector for vertebrate gene transfer
US7985739B2 (en) 2003-06-04 2011-07-26 The Board Of Trustees Of The Leland Stanford Junior University Enhanced sleeping beauty transposon system and methods for using the same
US7919583B2 (en) 2005-08-08 2011-04-05 Discovery Genomics, Inc. Integration-site directed vector systems
CA2692501C (en) 2007-07-04 2017-10-10 Max-Delbrueck-Centrum Fuer Molekulare Medizin Hyperactive variants of the transposase protein of the transposon system sleeping beauty
WO2011153440A2 (en) 2010-06-04 2011-12-08 Regents Of The University Of Minnesota Transposon mutagenesis system and methods of use
EP3092308A1 (en) 2014-01-07 2016-11-16 Fundacio Privada Institut de Medicina Predictiva i Personalitzada del Cancer Method for generating double stranded dna libraries and sequencing methods for the identification of methylated cytosines
BR112020000406A2 (en) * 2017-07-10 2022-09-13 Inst De Biologia Molecular Do Parana Ibmp GENETIC PLATFORM FOR HETEROLOGOUS OVEREXPRESSION ASSOCIATED WITH THE SELECTION OF HIGHLY PROTEIN PRODUCING CELLS
JP7337773B2 (en) 2017-07-29 2023-09-04 ジュノー セラピューティクス インコーポレイテッド Reagents for expanding cells expressing recombinant receptors
CN111542596A (en) 2017-11-01 2020-08-14 朱诺治疗学股份有限公司 Methods of producing therapeutic compositions of engineered cells
JP7258899B2 (en) 2017-11-01 2023-04-17 ジュノー セラピューティクス インコーポレイテッド Methods for making T cell compositions
CN112004824B (en) 2017-12-08 2024-09-13 朱诺治疗学股份有限公司 Process for producing engineered T cell compositions
CN115087868A (en) 2019-11-05 2022-09-20 朱诺治疗学股份有限公司 Methods of determining attributes of therapeutic T cell compositions
US20230144097A1 (en) * 2020-03-30 2023-05-11 Institute Of Zoology, Chinese Academy Of Sciences Active dna transposon systems and methods for use thereof
CN115803824A (en) 2020-05-13 2023-03-14 朱诺治疗学股份有限公司 Methods of identifying characteristics associated with clinical response and uses thereof
AU2022241654A1 (en) 2021-03-22 2023-09-28 Juno Therapeutics, Inc. Methods of determining potency of a therapeutic cell composition
WO2023122716A1 (en) 2021-12-22 2023-06-29 Vanderbilt University Next generation transpososomes
WO2023230548A1 (en) 2022-05-25 2023-11-30 Celgene Corporation Method for predicting response to a t cell therapy
WO2023230272A1 (en) 2022-05-27 2023-11-30 Kite Pharma, Inc. Non-viral delivery of cell therapy constructs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU731615B2 (en) * 1996-02-09 2001-04-05 Het Nederlands Kanker Instituut Vectors and methods for providing cells with additional nucleic acid material integrated in the genome of said cells
DK0973928T3 (en) * 1997-03-11 2010-08-09 Univ Minnesota DNA-based transposon system for introducing nucleic acid into DNA in a cell

Also Published As

Publication number Publication date
CA2309000A1 (en) 1999-05-27
WO1999025817A3 (en) 1999-08-05
WO1999025817A2 (en) 1999-05-27
EP1034258A2 (en) 2000-09-13
WO1999025817A9 (en) 1999-09-10
JP2001523450A (en) 2001-11-27

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase