AU1368797A - Arylethanolamine derivatives and their use as agonists of atypical beta-adrenoceptors - Google Patents

Arylethanolamine derivatives and their use as agonists of atypical beta-adrenoceptors

Info

Publication number
AU1368797A
AU1368797A AU13687/97A AU1368797A AU1368797A AU 1368797 A AU1368797 A AU 1368797A AU 13687/97 A AU13687/97 A AU 13687/97A AU 1368797 A AU1368797 A AU 1368797A AU 1368797 A AU1368797 A AU 1368797A
Authority
AU
Australia
Prior art keywords
adrenoceptors
agonists
atypical beta
arylethanolamine derivatives
arylethanolamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU13687/97A
Inventor
Malcolm Clive Carter
Michael Walter Foxton
Charles David Hartley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of AU1368797A publication Critical patent/AU1368797A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/24—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of a carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/31—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms
    • C07C311/35—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3882—Arylalkanephosphonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU13687/97A 1995-12-08 1996-12-06 Arylethanolamine derivatives and their use as agonists of atypical beta-adrenoceptors Abandoned AU1368797A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9525121.1A GB9525121D0 (en) 1995-12-08 1995-12-08 Chemical compounds
GB9525121 1995-12-08
PCT/EP1996/005470 WO1997021666A1 (en) 1995-12-08 1996-12-06 Arylethanolamine derivatives and their use as agonists of atypical beta-adrenoceptors

Publications (1)

Publication Number Publication Date
AU1368797A true AU1368797A (en) 1997-07-03

Family

ID=10785127

Family Applications (1)

Application Number Title Priority Date Filing Date
AU13687/97A Abandoned AU1368797A (en) 1995-12-08 1996-12-06 Arylethanolamine derivatives and their use as agonists of atypical beta-adrenoceptors

Country Status (3)

Country Link
AU (1) AU1368797A (en)
GB (1) GB9525121D0 (en)
WO (1) WO1997021666A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9929297D0 (en) * 1999-12-11 2000-02-02 Glaxo Group Ltd Process
GB0102407D0 (en) 2001-01-31 2001-03-14 Glaxo Group Ltd Process
US7709677B2 (en) 2001-01-31 2010-05-04 Glaxosmithkline Llc Process of preparing arylethanoldiamines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4154761A (en) * 1976-02-09 1979-05-15 Allen & Hanburys Limited Pharmacologically active compounds
DE3428526A1 (en) * 1984-08-02 1986-02-13 Boehringer Mannheim Gmbh, 6800 Mannheim NEW AMINO ALCOHOLS, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THIS COMPOUND
NO179246C (en) * 1991-11-20 1996-09-04 Sankyo Co Aromatic amino-alcohol derivatives and intermediates for their preparation
WO1995033724A1 (en) * 1994-06-09 1995-12-14 Glaxo Group Limited Phenethanolamine derivatives and their use as atypical beta-adrenoceptor agonists

Also Published As

Publication number Publication date
GB9525121D0 (en) 1996-02-07
WO1997021666A1 (en) 1997-06-19

Similar Documents

Publication Publication Date Title
AU6157396A (en) Bis-arylsulfonylaminobenzamide derivatives and the use there of as factor xa inhibitors
AU4105796A (en) Signage articles and methods of making same
AU6763898A (en) Gel sensors and methods of use thereof
AU5722796A (en) Cyclobutane derivatives and their use as inhibitors of prote in farnesyltransferase
AU8140898A (en) Inhibitors of beta-lactamases and uses therefor
AU3640997A (en) Iontophoretic delivery of integrin inhibitors
AU7812998A (en) Versatile stereotactic device and methods of use
AU3145595A (en) Display and decorative fixture apparatus
AU2457299A (en) Advertising device and method for use at point of sale
PL331047A1 (en) Novel amidinic derivatives and their application as inhibitors of thrombosin
AU5132296A (en) Protective coating compositions and methods of use thereof
AU4479997A (en) Sustained delivery device and methods of making and using the same
AU5671596A (en) E6ap antisense constructs and methods of use
AU4357296A (en) Benzene-fused heterocyclic derivatives and use of the same
AU2737295A (en) Phenethanolamine derivatives and their use as atypical beta-adrenoceptor agonists
AU7621496A (en) Microsensor and use of such microsensor
EP0824349A4 (en) Inhibitors of bacterial sialidase and methods of making and using the same
AU3124897A (en) Cationic lipids and methods of use therefor
AU2972199A (en) Apoptosis inducing molecule ii and methods of use
HUP9900911A3 (en) Esters and amides as pla2 inhibitors
AU1368797A (en) Arylethanolamine derivatives and their use as agonists of atypical beta-adrenoceptors
AU5702698A (en) Polyprolyl inhibitors of cyclophilin
AU6412599A (en) Oxybutynin formulations and methods of use
AU7227996A (en) Fluoroalkenyl derivatives and liquid crystal compositions
AU2949192A (en) Arylethanolamine derivatives and their use as beta-3-adrenoceptor agonists