AU1336701A - Functional cloning of genes encoding proteins/enzymes involved in proteolytic cleavage - Google Patents

Functional cloning of genes encoding proteins/enzymes involved in proteolytic cleavage

Info

Publication number
AU1336701A
AU1336701A AU13367/01A AU1336701A AU1336701A AU 1336701 A AU1336701 A AU 1336701A AU 13367/01 A AU13367/01 A AU 13367/01A AU 1336701 A AU1336701 A AU 1336701A AU 1336701 A AU1336701 A AU 1336701A
Authority
AU
Australia
Prior art keywords
genes encoding
proteolytic cleavage
enzymes involved
encoding proteins
functional cloning
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU13367/01A
Inventor
Barbara Cordell
Yonghong Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scios LLC
Original Assignee
Scios LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scios LLC filed Critical Scios LLC
Publication of AU1336701A publication Critical patent/AU1336701A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • C12N9/6475—Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU13367/01A 1999-10-20 2000-10-19 Functional cloning of genes encoding proteins/enzymes involved in proteolytic cleavage Abandoned AU1336701A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US16055999P 1999-10-20 1999-10-20
US60160559 1999-10-20
US22556400P 2000-08-14 2000-08-14
US60225564 2000-08-14
PCT/US2000/028941 WO2001029232A2 (en) 1999-10-20 2000-10-19 Functional cloning of genes encoding proteins/enzymes involved in proteolytic cleavage

Publications (1)

Publication Number Publication Date
AU1336701A true AU1336701A (en) 2001-04-30

Family

ID=26856991

Family Applications (1)

Application Number Title Priority Date Filing Date
AU13367/01A Abandoned AU1336701A (en) 1999-10-20 2000-10-19 Functional cloning of genes encoding proteins/enzymes involved in proteolytic cleavage

Country Status (2)

Country Link
AU (1) AU1336701A (en)
WO (1) WO2001029232A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0517293D0 (en) * 2005-08-24 2005-10-05 Cancer Rec Tech Ltd Vectors and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0691409B1 (en) * 1994-07-07 2002-10-23 Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO Modified proenzymes as substrates for proteolytic enzymes
US6379950B1 (en) * 1998-01-09 2002-04-30 Thomas Jefferson University Recombinant, active caspases and uses thereof
IL129427A0 (en) * 1999-04-13 2000-02-17 Yeda Res & Dev Preparation of biologically active molecules

Also Published As

Publication number Publication date
WO2001029232A8 (en) 2003-10-23
WO2001029232A9 (en) 2002-08-15
WO2001029232A3 (en) 2002-03-21
WO2001029232A2 (en) 2001-04-26

Similar Documents

Publication Publication Date Title
AU2001291649A1 (en) Nucleic acids encoding polypeptides having proteolytic activity
AU2002214531A1 (en) Proteins and nucleic acids encoding same
AU2001292842A1 (en) Compositions and methods relating to prostate specific genes and proteins
AU2001288390A1 (en) Proteins and nucleic acids encoding same
AU2002312627A1 (en) Nucleic acids encoding glucosinolate biosynthesis enzymes and methods of their use
AU2002221755A1 (en) Nucleotide and polypeptide sequence of human lysosomal acid lipase
AU2002214542A1 (en) Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
AU2001278655A1 (en) Novel nucleic acid and amino acid sequences
WO2001049831A3 (en) Xylosyltransferase and isoforms thereof
WO2002094870A8 (en) Proteins and nucleic acids encoding same
AU1336701A (en) Functional cloning of genes encoding proteins/enzymes involved in proteolytic cleavage
AU1183200A (en) Novel gene encoding brain-specific membrane protein
AU5178698A (en) Novel serine protease inhibitor nucleic acid molecules, proteins and uses hereof
AU2002239570A1 (en) Polypeptide sequences of drug metabolizing enzymes and polynucleotide sequences coding therefor
AU2001288363A1 (en) Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
AU3955099A (en) Novel gene and protein encoded thereby
AU2001273287A1 (en) Large scale expression and purification of recombinant proteins
AU2002211681A1 (en) Proteins and nucleic acids encoding same
AU2001264245A1 (en) Novel enzyme gene and its expression product
AU2001253639A1 (en) Sulfamide and bis-sulfamide amino acid derivatives as inhibitors of proteolytic enzymes
AU2001259240A1 (en) Novel stmst protein and nucleic acid mocecules and uses therefor
AU2003218112A1 (en) Nucleotide sequences and amino acid sequences of secreted proteins involved in angiogenesis
AU2002229060A1 (en) Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
AU2002227445A1 (en) Proteins and nucleic acids encoding same
AU2002236579A1 (en) Compositions and methods relating to prostate specific genes and proteins

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase