AU1200799A - Isopropyl ester prodrugs of indole spla2 inhibitors - Google Patents

Isopropyl ester prodrugs of indole spla2 inhibitors

Info

Publication number
AU1200799A
AU1200799A AU12007/99A AU1200799A AU1200799A AU 1200799 A AU1200799 A AU 1200799A AU 12007/99 A AU12007/99 A AU 12007/99A AU 1200799 A AU1200799 A AU 1200799A AU 1200799 A AU1200799 A AU 1200799A
Authority
AU
Australia
Prior art keywords
isopropyl ester
ester prodrugs
spla2 inhibitors
indole spla2
indole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU12007/99A
Inventor
Michael Lyle Denney
John Michael Morin
Daniel Jon Sall
Jason Scott Sawyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of AU1200799A publication Critical patent/AU1200799A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
AU12007/99A 1997-10-27 1998-10-26 Isopropyl ester prodrugs of indole spla2 inhibitors Abandoned AU1200799A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6328497P 1997-10-27 1997-10-27
US60063284 1997-10-27
PCT/US1998/022678 WO1999021545A1 (en) 1997-10-27 1998-10-26 ISOPROPYL ESTER PRODRUGS OF INDOLE sPLA2 INHIBITORS

Publications (1)

Publication Number Publication Date
AU1200799A true AU1200799A (en) 1999-05-17

Family

ID=22048190

Family Applications (1)

Application Number Title Priority Date Filing Date
AU12007/99A Abandoned AU1200799A (en) 1997-10-27 1998-10-26 Isopropyl ester prodrugs of indole spla2 inhibitors

Country Status (2)

Country Link
AU (1) AU1200799A (en)
WO (1) WO1999021545A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999009978A1 (en) * 1997-08-28 1999-03-04 Eli Lilly And Company Method for treatment of non-rheumatoid athritis
CA2309135A1 (en) * 1997-10-27 1999-05-06 Michael Lyle Denney N,n-diethylglycolamido ester prodrugs of indole spla2 inhibitors
ES2241178T3 (en) * 1997-10-27 2005-10-16 Eli Lilly And Company SPAR 2 INHIBITORS OF MORLINO-N-ETILO INHIBITORS OF SPLA 2.
DE19962300A1 (en) * 1999-12-23 2001-06-28 Asta Medica Ag New N-benzylindolyl glyoxylic acid derivatives are useful as antitumor agents
EP1303262A2 (en) * 2000-07-14 2003-04-23 Eli Lilly And Company Use of a spla2 inhibitor for the treatment of sepsis
AUPS282602A0 (en) 2002-06-07 2002-06-27 Garvan Institute Of Medical Research Method of inhibiting cell proliferation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA47387C2 (en) * 1994-04-01 2002-07-15 Елі Ліллі Енд Компані 1H-INDOLE-3-GLYOXYLAMIDES AS INHIBITORS OF sPLA2 AND PHARMACEUTICAL COMPOSITION ON THEIR BASIS

Also Published As

Publication number Publication date
WO1999021545A1 (en) 1999-05-06

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase