AU1174700A - Pharmaceutical compositions comprising porphyrins and some novel porphyrin derivatives - Google Patents

Pharmaceutical compositions comprising porphyrins and some novel porphyrin derivatives

Info

Publication number
AU1174700A
AU1174700A AU11747/00A AU1174700A AU1174700A AU 1174700 A AU1174700 A AU 1174700A AU 11747/00 A AU11747/00 A AU 11747/00A AU 1174700 A AU1174700 A AU 1174700A AU 1174700 A AU1174700 A AU 1174700A
Authority
AU
Australia
Prior art keywords
porphyrins
pharmaceutical compositions
porphyrin derivatives
novel porphyrin
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU11747/00A
Inventor
David Aviezer
Zeev Gross
Avner Yayon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Technion Research and Development Foundation Ltd
Yeda Research and Development Co Ltd
Original Assignee
Technion Research and Development Foundation Ltd
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technion Research and Development Foundation Ltd, Yeda Research and Development Co Ltd filed Critical Technion Research and Development Foundation Ltd
Publication of AU1174700A publication Critical patent/AU1174700A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4425Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU11747/00A 1998-11-08 1999-11-08 Pharmaceutical compositions comprising porphyrins and some novel porphyrin derivatives Abandoned AU1174700A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL126953 1998-11-08
IL12695398A IL126953A0 (en) 1998-11-08 1998-11-08 Pharmaceutical compositions comprising porphyrins and some novel porphyrin derivatives
PCT/IL1999/000602 WO2000027379A2 (en) 1998-11-08 1999-11-08 Pharmaceutical compositions comprising porphyrins and some novel porphyrin derivatives

Publications (1)

Publication Number Publication Date
AU1174700A true AU1174700A (en) 2000-05-29

Family

ID=11072118

Family Applications (1)

Application Number Title Priority Date Filing Date
AU11747/00A Abandoned AU1174700A (en) 1998-11-08 1999-11-08 Pharmaceutical compositions comprising porphyrins and some novel porphyrin derivatives

Country Status (4)

Country Link
US (1) US6730666B1 (en)
AU (1) AU1174700A (en)
IL (2) IL126953A0 (en)
WO (1) WO2000027379A2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE448226T1 (en) 2000-09-01 2009-11-15 Novartis Vaccines & Diagnostic AZA HETEROCYCLIC DERIVATIVES AND THEIR THERAPEUTIC USE
PT1650203E (en) 2000-09-11 2008-05-13 Novartis Vaccines & Diagnostic Process of preparation of benzimidazol-2-yl quinolinone derivatives
CA2436326C (en) * 2001-01-09 2012-08-14 Merck Patent Gesellschaft Mit Beschraenkter Haftung Combination therapy using receptor tyrosine kinase inhibitors and angiogenesis inhibitors
BR0313743A (en) 2002-08-23 2005-07-05 Chiron Corp Benzimidazole quinolinones and uses of these
AU2003290699B2 (en) 2002-11-13 2009-08-27 Novartis Vaccines And Diagnostics, Inc. Methods of treating cancer and related methods
IL156495A0 (en) * 2003-06-17 2004-01-04 Prochon Biotech Ltd Use of fgfr3 antagonists for treating t cell mediated diseases
KR101167573B1 (en) 2003-11-07 2012-07-30 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 Pharmaceutically acceptable salts of quinolinone compounds having improved pharmaceutical properties
EA010834B1 (en) * 2004-03-29 2008-12-30 Инотек Фармасьютикалз Корпорейшн Pyridyl-substituted porphyrin compounds and methods of use thereof
JP5545925B2 (en) 2005-05-17 2014-07-09 ノバルティス アーゲー Method for synthesizing heterocyclic compounds
CA2609353C (en) 2005-05-23 2015-04-28 Novartis Ag Crystalline and other forms of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]-1h-quinolin-2-one lactic acid salts
EP1928467A4 (en) * 2005-09-28 2009-11-04 Inotek Pharmaceuticals Corp N-benzyl substituted pyridyl porphyrin compounds and methods of use thereof
PT1957074E (en) 2005-11-29 2014-06-25 Novartis Ag Formulations of quinolinones
US8791099B2 (en) 2007-08-28 2014-07-29 Technion Research And Development Foundation Ltd. Transition metal complexes of corroles for preventing cardiovascular diseases or disorders
US20110098262A1 (en) * 2008-01-31 2011-04-28 Yondim Moussa B H Corroles for neuroprotection and neurorescue
US9642860B2 (en) 2011-08-15 2017-05-09 Technion Research & Development Foundation Limited Combinations of corroles and statins
EP2911662A4 (en) * 2012-10-25 2016-09-28 Technion Res & Dev Foundation Method of treatment of disease
US9364537B2 (en) * 2014-08-22 2016-06-14 University Of Dayton Transition metal porphyrin complexes and methods of treatment using same
US10035806B2 (en) 2015-10-06 2018-07-31 California Institute Of Technology Derivatized corroles and metallocorroles and their use as imaging and therapeutic agents
ES2877612T3 (en) 2015-10-30 2021-11-17 Inst Nat Sante Rech Med Porphyrin derivatives, their preparation procedure and their use to treat viral infections
JP6805470B2 (en) * 2016-01-04 2020-12-23 国立大学法人山梨大学 CLEC-2 antagonist, platelet aggregation inhibitor, antithrombotic drug, antimetastasis drug, anti-arthritis drug, compound having porphyrin skeleton, and method for producing the same.
US20220071956A1 (en) * 2018-12-27 2022-03-10 Nissan Chemical Corporation Composition for supressing secretion of extracellular vesicles

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60126291A (en) 1983-03-14 1985-07-05 Koichi Shiyudo Porphyrin derivative
US4977177A (en) 1985-04-30 1990-12-11 Nippon Petrochemicals Company, Ltd. Tetrapyrrole polyaminomonocarboxylic acid therapeutic agents
EP0330799A1 (en) 1988-03-03 1989-09-06 Schering Aktiengesellschaft A method for the treatment of arthritis and inflammatory joint diseases
JPS62161725A (en) 1986-07-29 1987-07-17 Noboru Iijima Preventive agent for malignant tumor
US5284647A (en) 1988-03-18 1994-02-08 Schering Aktiengesellschaft Mesotetraphenylporphyrin complex compounds, process for their production and pharmaceutical agents containing them
US5192788A (en) 1988-05-23 1993-03-09 Georgia State University Foundation, Inc. Porphyrin antiviral compositions
FR2632187B1 (en) 1988-06-02 1990-09-14 Centre Nat Rech Scient METALLOPORPHYRIN DERIVATIVES, THEIR PREPARATION, THEIR THERAPEUTIC APPLICATION AND THEIR USE FOR THE PREPARATION OF HYBRID MOLECULES
US5272142A (en) 1989-03-06 1993-12-21 Board Of Regents, The University Of Texas System Expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles and methods for treating tumors
FR2656866B1 (en) 1990-01-10 1992-05-15 Cis Bio Int PORPHYRIN DERIVATIVES AND METALLOPORPHYRINS POTENTIALLY COUPLED TO A BIOLOGICALLY ACTIVE MOLECULE, AND PHARMACEUTICAL COMPOSITION CONTAINING THEM.
WO1993002192A1 (en) 1991-07-15 1993-02-04 Repligen Corporation Modified pf4 compositions and methods of use
DE69334009T2 (en) 1992-11-20 2006-11-23 The University Of British Columbia, Vancouver Method of activating photosensitive agents
AU6813694A (en) 1994-03-14 1995-10-03 Massachusetts Eye & Ear Infirmary Use of green porphyrins in ocular diagnosis and therapy
HUT76327A (en) * 1994-05-13 1997-08-28 Monsanto Co Pharmaceutical compositions catalyzing decomposition of peroxy-nitrite
FR2723694B1 (en) * 1994-08-19 1996-09-27 Oreal USE OF SALTS OF CATIONIC PORPHINE DERIVATIVES AS PHOTOSENSITIZERS OF GRAM-NEGATIVE BACTERIA
US5576013A (en) 1995-03-21 1996-11-19 Eastern Virginia Medical School Treating vascular and neoplastic tissues
GB9620486D0 (en) 1996-10-02 1996-11-20 Travis Adrian R L Flat panel 3D display
EP0988037A1 (en) * 1997-02-05 2000-03-29 Board Of Regents, The University Of Texas System Porphyrin compounds as telomerase inhibitors
WO2000009111A2 (en) * 1998-08-11 2000-02-24 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Inhibitors of amyloid formation

Also Published As

Publication number Publication date
IL143020A (en) 2010-04-15
US6730666B1 (en) 2004-05-04
WO2000027379A3 (en) 2001-08-23
IL126953A0 (en) 1999-09-22
WO2000027379A2 (en) 2000-05-18

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase