AU1166199A - Methods for identifying the toxic/pathologic effect of environmental stimuli on gene transcription - Google Patents

Methods for identifying the toxic/pathologic effect of environmental stimuli on gene transcription

Info

Publication number
AU1166199A
AU1166199A AU11661/99A AU1166199A AU1166199A AU 1166199 A AU1166199 A AU 1166199A AU 11661/99 A AU11661/99 A AU 11661/99A AU 1166199 A AU1166199 A AU 1166199A AU 1166199 A AU1166199 A AU 1166199A
Authority
AU
Australia
Prior art keywords
toxic
identifying
methods
gene transcription
environmental stimuli
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU11661/99A
Inventor
Timothy Bertram
Michael J. Browne
Peter Bugelski
Paul England
Ian Mitchell
Gwyn Morgan
Andrew Rut
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Ltd
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd, SmithKline Beecham Corp filed Critical SmithKline Beecham Ltd
Publication of AU1166199A publication Critical patent/AU1166199A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AU11661/99A 1997-11-20 1998-11-20 Methods for identifying the toxic/pathologic effect of environmental stimuli on gene transcription Abandoned AU1166199A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6624197P 1997-11-20 1997-11-20
US60066241 1997-11-20
PCT/GB1998/003445 WO1999027090A1 (en) 1997-11-20 1998-11-20 Methods for identifying the toxic/pathologic effect of environmental stimuli on gene transcription

Publications (1)

Publication Number Publication Date
AU1166199A true AU1166199A (en) 1999-06-15

Family

ID=22068220

Family Applications (1)

Application Number Title Priority Date Filing Date
AU11661/99A Abandoned AU1166199A (en) 1997-11-20 1998-11-20 Methods for identifying the toxic/pathologic effect of environmental stimuli on gene transcription

Country Status (5)

Country Link
EP (1) EP1032663A1 (en)
JP (1) JP2001524311A (en)
AU (1) AU1166199A (en)
CA (1) CA2310621A1 (en)
WO (1) WO1999027090A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6593084B2 (en) * 1998-10-13 2003-07-15 Robert E. Bird Carcinogen assay
US6852845B1 (en) 1999-11-22 2005-02-08 Curagen Corporation Method of identifying toxic agents using NSAID-induced differential gene expression in liver
KR20030009531A (en) * 2000-06-14 2003-01-29 비스타겐 인코포레이티드 Toxicity typing using mesenchymal stem cells
EP1290444B1 (en) * 2000-06-14 2009-10-07 Vistagen, Inc. Toxicity typing using liver stem cells
US7590493B2 (en) 2000-07-31 2009-09-15 Ocimum Biosolutions, Inc. Methods for determining hepatotoxins
JP2002065259A (en) * 2000-08-24 2002-03-05 Shinya Watanabe Method for labeling nucleic acid and kit therefor
FR2819524B1 (en) * 2001-01-18 2003-07-04 Antonios Vekris DIFFERENTIAL COMPETITION HYBRIDIZATION
WO2002059560A2 (en) * 2001-01-23 2002-08-01 Gene Logic, Inc. A method and system for predicting the biological activity, including toxicology and toxicity, of substances
CA2447357A1 (en) 2001-05-22 2002-11-28 Gene Logic, Inc. Molecular toxicology modeling
KR20020096559A (en) * 2001-06-21 2002-12-31 이준호 Discovery of genes specifically regulated by alcohol
CA2452897A1 (en) * 2001-07-10 2003-08-21 Gene Logic, Inc. Cardiotoxin molecular toxicology modeling
US7447594B2 (en) 2001-07-10 2008-11-04 Ocimum Biosolutions, Inc. Molecular cardiotoxicology modeling
JP4836403B2 (en) * 2001-08-24 2011-12-14 独立行政法人産業技術総合研究所 Method for detecting toxic substances
CA2471661A1 (en) * 2002-01-31 2003-08-07 Gene Logic, Inc. Molecular hepatotoxicology modeling
US7469185B2 (en) 2002-02-04 2008-12-23 Ocimum Biosolutions, Inc. Primary rat hepatocyte toxicity modeling
AU2003261168A1 (en) * 2002-07-19 2004-02-09 Althea Technologies, Inc. Strategies for gene expression analysis
AU2003284921A1 (en) * 2002-10-22 2004-05-13 Iconix Pharmaceuticals, Inc. Reticulocyte depletion signatures
JP2007501617A (en) * 2003-08-07 2007-02-01 ジーン ロジック インコーポレイテッド Primary rat hepatotoxicity modeling

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994017208A1 (en) * 1993-01-21 1994-08-04 President And Fellows Of Harvard College Methods and diagnostic kits utilizing mammalian stress promoters to determine toxicity of a compound
WO1997013877A1 (en) * 1995-10-12 1997-04-17 Lynx Therapeutics, Inc. Measurement of gene expression profiles in toxicity determination
US6156502A (en) * 1995-12-21 2000-12-05 Beattie; Kenneth Loren Arbitrary sequence oligonucleotide fingerprinting

Also Published As

Publication number Publication date
EP1032663A1 (en) 2000-09-06
WO1999027090A1 (en) 1999-06-03
JP2001524311A (en) 2001-12-04
CA2310621A1 (en) 1999-06-03

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase