AU1164597A - Ifosfamide, analogues thereof and their preparation - Google Patents

Ifosfamide, analogues thereof and their preparation

Info

Publication number
AU1164597A
AU1164597A AU11645/97A AU1164597A AU1164597A AU 1164597 A AU1164597 A AU 1164597A AU 11645/97 A AU11645/97 A AU 11645/97A AU 1164597 A AU1164597 A AU 1164597A AU 1164597 A AU1164597 A AU 1164597A
Authority
AU
Australia
Prior art keywords
ifosfamide
analogues
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU11645/97A
Inventor
William Paul Armstrong
Joseph John Brennan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Darwin Discovery Ltd
Original Assignee
Chiroscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9525891.9A external-priority patent/GB9525891D0/en
Priority claimed from GBGB9602519.2A external-priority patent/GB9602519D0/en
Application filed by Chiroscience Ltd filed Critical Chiroscience Ltd
Publication of AU1164597A publication Critical patent/AU1164597A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/062—Organo-phosphoranes without P-C bonds
    • C07F9/065—Phosphoranes containing the structure P=N-
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
    • C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
AU11645/97A 1995-12-19 1996-12-19 Ifosfamide, analogues thereof and their preparation Abandoned AU1164597A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9525891 1995-12-19
GBGB9525891.9A GB9525891D0 (en) 1995-12-19 1995-12-19 Therapeutic agents and their preparation
GB9602519 1996-02-08
GBGB9602519.2A GB9602519D0 (en) 1996-02-08 1996-02-08 Cyclisation
PCT/GB1996/003157 WO1997022614A1 (en) 1995-12-19 1996-12-19 Ifosfamide, analogues thereof and their preparation

Publications (1)

Publication Number Publication Date
AU1164597A true AU1164597A (en) 1997-07-14

Family

ID=26308323

Family Applications (1)

Application Number Title Priority Date Filing Date
AU11645/97A Abandoned AU1164597A (en) 1995-12-19 1996-12-19 Ifosfamide, analogues thereof and their preparation

Country Status (3)

Country Link
EP (1) EP0876381A1 (en)
AU (1) AU1164597A (en)
WO (1) WO1997022614A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1165570E (en) * 1999-03-05 2007-01-31 Metabasis Therapeutics Inc Novel phosphorus-containing prodrugs
US7205404B1 (en) 1999-03-05 2007-04-17 Metabasis Therapeutics, Inc. Phosphorus-containing prodrugs
JP2017512183A (en) 2014-02-13 2017-05-18 リガンド・ファーマシューティカルズ・インコーポレイテッド Prodrug compounds and their use
US9994600B2 (en) 2014-07-02 2018-06-12 Ligand Pharmaceuticals, Inc. Prodrug compounds and uses therof
WO2017044453A1 (en) * 2015-09-10 2017-03-16 Becton, Dickinson And Company Cyclophosphamide analogs for use as immunogens and assay conjugates for an immunoassay of cyclophosphamide and ifosfamide
WO2019060269A1 (en) 2017-09-21 2019-03-28 Becton, Dickinson And Company Hazardous contaminant collection kit and rapid testing
AU2020215639A1 (en) 2019-01-28 2021-08-05 Becton, Dickinson And Company Hazardous contaminant collection device with integrated swab and test device
CN114965770B (en) * 2022-05-24 2023-03-28 江苏海洋大学 Method for detecting starting material, impurity D and impurity F in ifosfamide bulk drug

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL100390B1 (en) * 1975-10-06 1978-09-30 METHOD FOR THE PRODUCTION OF 2-OXIDE-2- / BIS / 2-CHLOROETHYL / -AMINO / -1- / OXO-3-AZA-2-PHOSPHACYCLOHEXANE / CYCLOPHOSPHAMIDE / OPTICAL
PL150330B1 (en) * 1987-06-13 1990-05-31 Method of obtaining derivatives of 1,3,2-oxazaphosphorinate
GB9412689D0 (en) * 1994-06-23 1994-08-10 Chiroscience Ltd Cytotoxic agent and its use
GB9412618D0 (en) * 1994-06-23 1994-08-10 Chiroscience Ltd Cytotoxic agent and its use
DE4425070A1 (en) * 1994-07-15 1996-01-18 Degussa Process for the preparation of optically active l-substituted 2- (aminomethyl) pyrrolidines
GB9502637D0 (en) * 1995-02-08 1995-03-29 Chiroscience Ltd Reduction

Also Published As

Publication number Publication date
WO1997022614A1 (en) 1997-06-26
EP0876381A1 (en) 1998-11-11

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