AU1115797A - Protective protein/cathepsin a and precursor: crystallization, x-ray diffraction, three-dimensional structure determination and rational drug design - Google Patents

Protective protein/cathepsin a and precursor: crystallization, x-ray diffraction, three-dimensional structure determination and rational drug design

Info

Publication number
AU1115797A
AU1115797A AU11157/97A AU1115797A AU1115797A AU 1115797 A AU1115797 A AU 1115797A AU 11157/97 A AU11157/97 A AU 11157/97A AU 1115797 A AU1115797 A AU 1115797A AU 1115797 A AU1115797 A AU 1115797A
Authority
AU
Australia
Prior art keywords
cathepsin
crystallization
precursor
ray diffraction
dimensional structure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU11157/97A
Inventor
Alessandra D'azzo
Wim G. J. Hol
Gabrielle Rudenko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WIM G J HOL
Original Assignee
WIM G J HOL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WIM G J HOL filed Critical WIM G J HOL
Publication of AU1115797A publication Critical patent/AU1115797A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
AU11157/97A 1995-10-26 1996-10-25 Protective protein/cathepsin a and precursor: crystallization, x-ray diffraction, three-dimensional structure determination and rational drug design Abandoned AU1115797A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US597695P 1995-10-26 1995-10-26
US005976 1995-10-26
US680295P 1995-11-15 1995-11-15
US006802 1995-11-15
PCT/US1996/017325 WO1997015588A1 (en) 1995-10-26 1996-10-25 Protective protein/cathepsin a and precursor: crystallization, x-ray diffraction, three-dimensional structure determination and rational drug design

Publications (1)

Publication Number Publication Date
AU1115797A true AU1115797A (en) 1997-05-15

Family

ID=26674999

Family Applications (1)

Application Number Title Priority Date Filing Date
AU11157/97A Abandoned AU1115797A (en) 1995-10-26 1996-10-25 Protective protein/cathepsin a and precursor: crystallization, x-ray diffraction, three-dimensional structure determination and rational drug design

Country Status (2)

Country Link
AU (1) AU1115797A (en)
WO (1) WO1997015588A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6183121B1 (en) 1997-08-14 2001-02-06 Vertex Pharmaceuticals Inc. Hepatitis C virus helicase crystals and coordinates that define helicase binding pockets
AU1187599A (en) * 1997-10-14 1999-05-03 E.I. Du Pont De Nemours And Company Trihydroxynaphthalene reductase: methods for three-dimensional structure determinations and rational inhibitor design
US6842704B2 (en) 1998-02-04 2005-01-11 Immunex Corporation Crystalline TNF-α-converting enzyme and uses thereof
JP2004503202A (en) * 1998-02-04 2004-02-05 イミュネックス　コーポレイション Crystalline TNF-α converting enzyme and use thereof
US7383135B1 (en) 1998-05-04 2008-06-03 Vertex Pharmaceuticals Incorporated Methods of designing inhibitors for JNK kinases
WO2001055443A1 (en) * 2000-01-31 2001-08-02 Pharmacia & Upjohn Company Crystallization and structure determination of staphylococcus aureus nad synthetase
US7736875B2 (en) 2000-09-08 2010-06-15 Prozymex A/S Dipeptidyl peptidase I crystal structure and its uses
DK1317555T3 (en) * 2000-09-08 2008-03-25 Prozymex As Dipeptidyl peptidase in crystal structure and applications thereof
US6869792B2 (en) * 2001-03-16 2005-03-22 Irm, Llc Method and apparatus for performing multiple processing steps on a sample in a single vessel
AU2004290298A1 (en) 2003-10-24 2005-05-26 Gilead Sciences, Inc. Methods and compositions for identifying therapeutic compounds
LT2751279T (en) 2011-08-31 2017-12-11 St. Jude Children`S Research Hospital Methods and compositions to detect the level of lysosomal exocytosis activity and methods of use

Also Published As

Publication number Publication date
WO1997015588A1 (en) 1997-05-01

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