ATE97653T1 - (r)5-pentylamino-5-oxopentanesaeure-derivate mit anticholecystokininwirkung. - Google Patents

(r)5-pentylamino-5-oxopentanesaeure-derivate mit anticholecystokininwirkung.

Info

Publication number
ATE97653T1
ATE97653T1 AT88901259T AT88901259T ATE97653T1 AT E97653 T1 ATE97653 T1 AT E97653T1 AT 88901259 T AT88901259 T AT 88901259T AT 88901259 T AT88901259 T AT 88901259T AT E97653 T1 ATE97653 T1 AT E97653T1
Authority
AT
Austria
Prior art keywords
oxopentanacid
anticholecystokin
pentylamino
derivatives
action
Prior art date
Application number
AT88901259T
Other languages
English (en)
Inventor
Francesco Makovec
Rolando Chiste
Walter Peris
Luigi Rovati
Original Assignee
Rotta Research Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT8767076A external-priority patent/IT1217123B/it
Application filed by Rotta Research Lab filed Critical Rotta Research Lab
Application granted granted Critical
Publication of ATE97653T1 publication Critical patent/ATE97653T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/82—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/83—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
AT88901259T 1987-02-05 1988-01-28 (r)5-pentylamino-5-oxopentanesaeure-derivate mit anticholecystokininwirkung. ATE97653T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT8767076A IT1217123B (it) 1987-02-05 1987-02-05 Derivati otticamente attivi dell acido 5 pentilammino 5 oxo pentanoico r ad attivita antagonista della colecistochinina e procedimento per la loro preparazione
PCT/EP1988/000061 WO1988005774A1 (en) 1987-02-05 1988-01-28 Derivatives of (r) 5-pentylamino-5-oxopentanoic acid with anticholecystokinin activity
EP88901259A EP0344184B1 (de) 1987-02-05 1988-01-28 (r)5-pentylamino-5-oxopentanesäure-derivate mit anticholecystokininwirkung

Publications (1)

Publication Number Publication Date
ATE97653T1 true ATE97653T1 (de) 1993-12-15

Family

ID=26119032

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88901259T ATE97653T1 (de) 1987-02-05 1988-01-28 (r)5-pentylamino-5-oxopentanesaeure-derivate mit anticholecystokininwirkung.

Country Status (1)

Country Link
AT (1) ATE97653T1 (de)

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties