ATE94763T1 - DRUG FOR THE TREATMENT OF FIBROTIC DISORDER AND ANTIFIBROTIC COMPOUND. - Google Patents

DRUG FOR THE TREATMENT OF FIBROTIC DISORDER AND ANTIFIBROTIC COMPOUND.

Info

Publication number
ATE94763T1
ATE94763T1 AT89300476T AT89300476T ATE94763T1 AT E94763 T1 ATE94763 T1 AT E94763T1 AT 89300476 T AT89300476 T AT 89300476T AT 89300476 T AT89300476 T AT 89300476T AT E94763 T1 ATE94763 T1 AT E94763T1
Authority
AT
Austria
Prior art keywords
interferon
treatment
fibrotic disorder
drug
human
Prior art date
Application number
AT89300476T
Other languages
German (de)
Inventor
Brian Berman
Matthew R Duncan
Original Assignee
Baker Cummins Dermatolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baker Cummins Dermatolog filed Critical Baker Cummins Dermatolog
Application granted granted Critical
Publication of ATE94763T1 publication Critical patent/ATE94763T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Human interferon is utilised in the manufacture of a medicament for the treatment of a fibrotic disorder. The medicament is administered to raise the total concentration of human interferons in the affected tissue area to about 10 to about 4 x 10<7> IU of interferon per cubic centimeter. The human interferon used can be naturally derived or recombinant DNA-derived alpha, beta or gamma-interferon. The interferon can be adminstered by any indicated conventional method and in any suitable, pharmaceutically acceptable, compatible vehicle.
AT89300476T 1988-01-25 1989-01-19 DRUG FOR THE TREATMENT OF FIBROTIC DISORDER AND ANTIFIBROTIC COMPOUND. ATE94763T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14797388A 1988-01-25 1988-01-25
EP89300476A EP0328255B1 (en) 1988-01-25 1989-01-19 A medicament for the treatment of a fibrotic disorder, and anti-fibrotic composition

Publications (1)

Publication Number Publication Date
ATE94763T1 true ATE94763T1 (en) 1993-10-15

Family

ID=22523687

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89300476T ATE94763T1 (en) 1988-01-25 1989-01-19 DRUG FOR THE TREATMENT OF FIBROTIC DISORDER AND ANTIFIBROTIC COMPOUND.

Country Status (6)

Country Link
EP (1) EP0328255B1 (en)
JP (1) JPH021411A (en)
AT (1) ATE94763T1 (en)
AU (2) AU2855189A (en)
CA (1) CA1327746C (en)
DE (1) DE68909267T2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL89662A (en) * 1989-03-19 1997-11-20 Interpharm Lab Ltd Kiryat Weiz Pharmaceutical compositions comprising interferon-beta
US5227158A (en) * 1991-06-10 1993-07-13 Genentech, Inc. Method of stimulating hepatocyte proliferation by administration of hepatocyte growth factor and gamma-interferon
JPH07501320A (en) * 1991-10-11 1995-02-09 ギリーズ，マーク・セドリック Treatment of ocular fibrosis with interferon alpha
AU669132B2 (en) * 1991-10-11 1996-05-30 Mark Cedric Gillies Treating ophthalmic fibrosis using interferon-alpha
US5863530A (en) * 1991-10-11 1999-01-26 Spruson & Ferguson Treating ophthalmic fibrosis using interferon-α
GB2304342A (en) * 1995-08-18 1997-03-19 Univ Manchester Pharmaceutical comprising either an inhibitor or a stimulator of interferon gamma
US20020025316A1 (en) 1995-08-18 2002-02-28 Ferguson Mark Williams James Pharmaceutical composition containing inhibitors of interferon-gamma
EP0795332B1 (en) * 1996-03-14 2005-06-01 Mondobiotech Interferon SA Medical use of gamma-interferon in interstitial lung diseases
CA2384331C (en) * 1999-09-09 2008-10-14 Hadasit Medical Research Services And Development Company Ltd. The use of halofuginone and related compounds for the treatment of urethral stricture by local administration
YU45103A (en) 2000-12-06 2006-08-17 Applied Research Systems Ars Holding N.V. Use of sarp-1 for the treatment and/or prevention of scleroderma
IL159784A0 (en) * 2001-07-20 2004-06-20 Intermune Inc Methods of treating liver fibrosis
CA2496577A1 (en) * 2002-08-28 2004-03-11 Intermune, Inc. Combination therapy for treatment of fibrotic disorders
US8465413B2 (en) 2010-11-25 2013-06-18 Coloplast A/S Method of treating Peyronie's disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3436638C2 (en) * 1984-10-05 1992-10-08 Bioferon biochemische Substanzen GmbH & Co, 7958 Laupheim Use of preparations containing interferon-gamma (IFN-gamma) for the treatment of rheumatic diseases
JPH052648A (en) * 1991-06-25 1993-01-08 Kobe Steel Ltd Picture data processor
JP3062305B2 (en) * 1991-06-26 2000-07-10 キヤノン株式会社 Fundus camera
JPH054380A (en) * 1991-06-28 1993-01-14 Fujitsu Ltd Face selective system

Also Published As

Publication number Publication date
DE68909267D1 (en) 1993-10-28
AU6820190A (en) 1991-03-14
JPH021411A (en) 1990-01-05
EP0328255A1 (en) 1989-08-16
EP0328255B1 (en) 1993-09-22
DE68909267T2 (en) 1994-04-28
JPH0561254B2 (en) 1993-09-06
AU2855189A (en) 1989-07-27
AU630530B2 (en) 1992-10-29
CA1327746C (en) 1994-03-15

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Legal Events

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