ATE8264T1 - Verfahren zur herstellung von aclacinomycinen und verwendete mikroorganismen. - Google Patents

Verfahren zur herstellung von aclacinomycinen und verwendete mikroorganismen.

Info

Publication number
ATE8264T1
ATE8264T1 AT81106922T AT81106922T ATE8264T1 AT E8264 T1 ATE8264 T1 AT E8264T1 AT 81106922 T AT81106922 T AT 81106922T AT 81106922 T AT81106922 T AT 81106922T AT E8264 T1 ATE8264 T1 AT E8264T1
Authority
AT
Austria
Prior art keywords
aclacinomycins
production
used microorganisms
microorganisms
streptomyces galilaeus
Prior art date
Application number
AT81106922T
Other languages
English (en)
Inventor
Akiko Fujiwara
Tatsuo Hoshino
Masaaki Tazoe
Original Assignee
F. Hoffmann-La Roche & Co. Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche & Co. Aktiengesellschaft filed Critical F. Hoffmann-La Roche & Co. Aktiengesellschaft
Application granted granted Critical
Publication of ATE8264T1 publication Critical patent/ATE8264T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
AT81106922T 1980-10-27 1981-09-04 Verfahren zur herstellung von aclacinomycinen und verwendete mikroorganismen. ATE8264T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8034537 1980-10-27
EP81106922A EP0050725B1 (de) 1980-10-27 1981-09-04 Verfahren zur Herstellung von Aclacinomycinen und verwendete Mikroorganismen

Publications (1)

Publication Number Publication Date
ATE8264T1 true ATE8264T1 (de) 1984-07-15

Family

ID=10516906

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81106922T ATE8264T1 (de) 1980-10-27 1981-09-04 Verfahren zur herstellung von aclacinomycinen und verwendete mikroorganismen.

Country Status (5)

Country Link
US (1) US4375511A (de)
EP (1) EP0050725B1 (de)
JP (1) JPS57105192A (de)
AT (1) ATE8264T1 (de)
DE (1) DE3164574D1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1187434A (en) * 1981-08-11 1985-05-21 Akihiro Yoshimoto Anthracycline antibiotics and their preparation method
US4405713A (en) * 1981-12-28 1983-09-20 Hoffmann-La Roche Inc. Process for the preparation of optically active anthracycline glycosides A and B
US5013549A (en) * 1989-02-16 1991-05-07 Board Of Trustees Operating Michigan State University Production, isolation, and identification of novel antifungal compounds
US4977084A (en) * 1989-02-16 1990-12-11 Board Of Trustees Operating Michigan State University Production, isolation, and identification of novel antifungal compounds
US5066585A (en) * 1990-07-09 1991-11-19 Board Of Trustees Operating Michigan State University Method of inhibiting fungus using novel antifungal compounds
KR970000591B1 (ko) * 1993-09-03 1997-01-14 동국제약 주식회사 신균주 스트렙토마이세스 라벤도폴리아 DKRS 및 이를 이용한 아클라시노마이신 A, B, Y 및 아글리콘(Aglycone)의 제조방법
US20150290232A1 (en) 2012-09-28 2015-10-15 Hangzhou Bensheng Pharmaceutical Co., Ltd. Drug composition for treating tumors and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4071411A (en) * 1974-07-27 1978-01-31 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Antitumor antibiotics aclacinomycins A and B [RD-9187A]
US4204038A (en) * 1976-04-07 1980-05-20 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Process for preparing antibiotics MA 144-M1 and MA 144-M2
US4209588A (en) * 1976-10-05 1980-06-24 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Process for producing new antitumor anthracycline antibiotics
ZA802929B (en) * 1979-05-22 1981-05-27 Hoffmann La Roche Novel tetracyclic compounds and process for the preparation thereof

Also Published As

Publication number Publication date
DE3164574D1 (en) 1984-08-09
US4375511A (en) 1983-03-01
JPS57105192A (en) 1982-06-30
EP0050725B1 (de) 1984-07-04
EP0050725A1 (de) 1982-05-05

Similar Documents

Publication Publication Date Title
DE3888274D1 (de) Vorrichtung zur intensiven und kontrollierten Herstellung von Mikroorganismen durch Photosynthese.
AT380694B (de) Verfahren zur herstellung von mikroorganismen
GT196000041A (es) Antibioticos a-21978 y procedimiento para su produccion
ES551945A0 (es) Procedimiento para preparar un compuesto de furano
GB8621911D0 (en) Increasing ratio of components of anti-biotic complex
ATE8264T1 (de) Verfahren zur herstellung von aclacinomycinen und verwendete mikroorganismen.
ATE95836T1 (de) Zum abbau von glycosaminoglycan faehige enzymzusammensetzung und verfahren zur herstellung dieser zusammensetzung.
JPS5417032B2 (de)
TW234147B (de)
HUT46662A (en) Process for producing alkyl-melatonins
DE3163322D1 (en) Fermentation process
FR2689518B1 (fr) Microorganismes, procédé de préparation et utilisation.
JPS5799200A (en) Production of acranomycins
ES8102591A1 (es) Procedimiento de produccion de antibioticos sisomicinicos.
ATE95568T1 (de) Mikrobiologisches verfahren zur herstellung von uk-61.689 und mikroorganismen zur verwendung darin.
NZ184320A (en) Neoviridogriseins 1,iiandiii from the culture of streptomyces sp' atcc 31289
GR3023467T3 (en) Heteropolysaccharide 35-80.
DE59108700D1 (de) Verfahren zur herstellung von 17-oxosteroiden
NO843446L (no) Antibiotikum sb 22484
ATE10936T1 (de) Verfahren zur herstellung von 2-alkoxy-4aminopyrimidinen.
GB2017690A (en) Pyrrolido Furoxans
RO100186A2 (ro) Compozitie din cauciuc compact pentru talpi usoare si procedeu de obtinre a acesteia
SU669588A1 (ru) Способ изготовления изделий из ячеистобетонных смесей
EP0322717A3 (en) Dactylocycline a and dactylocycline b
HUT46715A (en) Process for producing thermoplast composition

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee