ATE68348T1 - PHARMACEUTICAL AND COSMETIC COMPOSITIONS BASED ON BENZOYL PEROXIDE AND LIPOPHILIC QUATERNARY AMMONIUM SALICYLATES AND THEIR USE, PARTICULARLY IN THE TREATMENT OF ACNE. - Google Patents

PHARMACEUTICAL AND COSMETIC COMPOSITIONS BASED ON BENZOYL PEROXIDE AND LIPOPHILIC QUATERNARY AMMONIUM SALICYLATES AND THEIR USE, PARTICULARLY IN THE TREATMENT OF ACNE.

Info

Publication number
ATE68348T1
ATE68348T1 AT88118818T AT88118818T ATE68348T1 AT E68348 T1 ATE68348 T1 AT E68348T1 AT 88118818 T AT88118818 T AT 88118818T AT 88118818 T AT88118818 T AT 88118818T AT E68348 T1 ATE68348 T1 AT E68348T1
Authority
AT
Austria
Prior art keywords
denotes
pharmaceutical
quaternary ammonium
benzoyl peroxide
acne
Prior art date
Application number
AT88118818T
Other languages
German (de)
Inventor
Michel Philippe
Michel Hocquaux
Henri Sebag
Irina Beck
Jean-Pierre Laugier
Original Assignee
Oreal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oreal filed Critical Oreal
Application granted granted Critical
Publication of ATE68348T1 publication Critical patent/ATE68348T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
    • A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/38—Percompounds, e.g. peracids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A61K8/416—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Pharmaceutical or cosmetical composition, comprising a topical composition containing, in combination in a physiologically acceptable vehicle, benzoyl peroxide and at least one lipophilic quaternary ammonium salicylate corresponding to the general formula (I): <IMAGE> in which: (i) R1, R2, R3 and R4, which may be identical or different, denote an alkyl or alkylcycloalkyl radical, optionally substituted or interrupted; (ii) R3 and/or R4 denote(s) a group: R8OC2H3R7 n OCH2CHOH-CH2 p in which: 0 </= n </= 4 and p denotes 0 or 1; R8 denotes H or an alkyl, alkenyl, alkylcycloalkyl or alkylaryl radical; (iii) R4 denotes an alkylenephenyl radical; (iv) (v) R1 and R2 can form a saturated or unsaturated, aromatic or non-aromatic heterocycle; (vi) R1, R2 and R3, with the nitrogen atoms, form polycyclic derivatives; R5 denotes a group corresponding to the formula: <IMAGE> , in which n varies between 0 and 10.
AT88118818T 1987-11-24 1988-11-11 PHARMACEUTICAL AND COSMETIC COMPOSITIONS BASED ON BENZOYL PEROXIDE AND LIPOPHILIC QUATERNARY AMMONIUM SALICYLATES AND THEIR USE, PARTICULARLY IN THE TREATMENT OF ACNE. ATE68348T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8716280A FR2623395B1 (en) 1987-11-24 1987-11-24 PHARMACEUTICAL AND COSMETIC COMPOSITIONS BASED ON BENZOYL PEROXIDE AND QUATERNARY AMMONIUM LIPOPHILIC SALICYLATES AND THEIR USE, ESPECIALLY IN THE TREATMENT OF ACNE
EP88118818A EP0317846B1 (en) 1987-11-24 1988-11-11 Pharmaceutical and cosmetical compositions based on benzoyl peroxide and lipophilic quaternary ammonium salicylates and their use, in particular in treating acne

Publications (1)

Publication Number Publication Date
ATE68348T1 true ATE68348T1 (en) 1991-11-15

Family

ID=9357111

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88118818T ATE68348T1 (en) 1987-11-24 1988-11-11 PHARMACEUTICAL AND COSMETIC COMPOSITIONS BASED ON BENZOYL PEROXIDE AND LIPOPHILIC QUATERNARY AMMONIUM SALICYLATES AND THEIR USE, PARTICULARLY IN THE TREATMENT OF ACNE.

Country Status (7)

Country Link
US (1) US5019567A (en)
EP (1) EP0317846B1 (en)
JP (1) JP2683390B2 (en)
AT (1) ATE68348T1 (en)
CA (1) CA1330945C (en)
DE (1) DE3865638D1 (en)
FR (1) FR2623395B1 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204093A (en) * 1989-04-06 1993-04-20 Victor Steven A Shaving cream composition for the treatment of acne vulgaris and pseudofolliculitis barbae and method of producing and using same
FR2694934B1 (en) * 1992-08-24 1994-11-10 Oreal Composition for the treatment of acne containing a salicylic acid derivative and salicylic acid derivatives.
US5998392A (en) * 1996-04-10 1999-12-07 Gattefosse S.A. Benzoyl peroxide flocculent materials and methods of their preparation
FR2762839B1 (en) * 1997-04-30 2001-05-11 Oreal NOVEL SALICYLIC ACID DERIVATIVES AND THEIR USE IN A COSMETIC AND / OR DERMATOLOGICAL COMPOSITION
US6120756A (en) * 1998-08-19 2000-09-19 Philip I. Markowitz Topical anionic salicylate for disorders of the skin
US6451773B1 (en) 2000-03-31 2002-09-17 Cognis Corporation Chitosan formulation with azelaic acid and other actives for the treatment of acne
KR100822236B1 (en) * 2000-11-30 2008-04-16 토소가부시키가이샤 Resist release agent
US20060189552A1 (en) * 2000-12-12 2006-08-24 Mohan Vishnupad Dispenser for dispensing three or more actives
US7060732B2 (en) * 2000-12-12 2006-06-13 Imaginative Research Associates, Inc. Antibiotic/benzoyl peroxide dispenser
US7129275B2 (en) 2001-10-31 2006-10-31 Coreana Cosmetics Co., Ltd. Compositions for treating acne comprising phytandiol amine
US7776355B2 (en) * 2003-07-03 2010-08-17 Medics Pharmaceutical Corporation Delivery system for topical medications
US20050025817A1 (en) * 2003-07-03 2005-02-03 Bhatia Kuljit S. Delivery system for topical medications
US7662855B2 (en) * 2004-05-11 2010-02-16 Imaginative Research Associates, Inc. Retinoid solutions and formulations made therefrom
US20060014834A1 (en) * 2004-05-11 2006-01-19 Mohan Vishnupad Retinoid solutions and formulations made therefrom
US7479289B2 (en) * 2004-07-02 2009-01-20 Medicis Pharmaceutical Corporation Stable cleanser compositions containing sulfur
US7655682B2 (en) * 2004-07-02 2010-02-02 Medicis Pharmaceutical Corporation Triple anti-irritant composition
KR20070115939A (en) * 2005-03-10 2007-12-06 제이알 켐, 엘엘씨 Benzoyl peroxide compositions and methods of use
KR101352187B1 (en) 2005-03-10 2014-02-17 제이알 켐, 엘엘씨 Stable organic peroxide compositions
WO2007005471A2 (en) * 2005-06-29 2007-01-11 Jr Chem, Llc Stable organic peroxide compositions
WO2007002880A2 (en) * 2005-06-29 2007-01-04 Jr Chem, Llc Method of enhanced drug application
US20090306023A1 (en) * 2005-06-29 2009-12-10 Ramirez Jose E Stable organic peroxide compositions
US7556820B2 (en) 2005-06-29 2009-07-07 Jr Chem, Llc Stable organic peroxide compositions
BRPI0709674A2 (en) 2006-03-31 2011-12-06 Stiefel Res Australia Pty Ltd sparkling suspension gel
FR2981272A1 (en) 2011-10-14 2013-04-19 Inneov Lab USE OF AN ORAL COMPOSITION COMPRISING A MIXTURE OF AT LEAST ONE POLYPHENOL, ZINC, AND VITAMIN C.
GB201313423D0 (en) 2013-07-26 2013-09-11 Innospec Ltd Compositions and methods
GB201413355D0 (en) * 2014-07-28 2014-09-10 Innospec Ltd Compositons and methods
FR3075609B1 (en) * 2017-12-21 2020-05-22 L'oreal COMPOSITIONS COMPRISING SALICYLIC ACID OR A DERIVATIVE THEREOF, A SURFACTANT HAVING A HLB ABOVE OR MORE THAN 9.7, AND AT LEAST A THICKENING POLYMER

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3852210A (en) * 1972-08-11 1974-12-03 Flow Pharma Inc Stable liquid detergent concentrates containing active oxygen
FR2378523A1 (en) * 1977-01-26 1978-08-25 Grupper Charles ACNE TREATMENT MEDICINE
US4318907A (en) * 1978-04-04 1982-03-09 Westwood Pharmaceuticals, Inc. Method for treating acne vulgaris and compositions useful for that purpose
FR2469923A1 (en) * 1979-11-26 1981-05-29 Ile De France NEW MEDICINAL PRODUCT BASED ON ASPIRIN AND HEPTAMINOL
US4514385A (en) * 1981-10-05 1985-04-30 Alcon Laboratories, Inc. Anti-acne compositions
LU85111A1 (en) * 1983-12-01 1985-09-12 Oreal ANTI-ACNETIC COMPOSITION BASED ON BENZOYL PEROXIDE AND AT LEAST ONE SOLAR FILTER

Also Published As

Publication number Publication date
FR2623395A1 (en) 1989-05-26
CA1330945C (en) 1994-07-26
DE3865638D1 (en) 1991-11-21
JPH01165524A (en) 1989-06-29
EP0317846B1 (en) 1991-10-16
US5019567A (en) 1991-05-28
EP0317846A1 (en) 1989-05-31
FR2623395B1 (en) 1990-04-20
JP2683390B2 (en) 1997-11-26

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