ATE557091T1 - MOLECULES OF HDV NUCLEIC ACIDS, THEIR FRAGMENTS AND APPLICATIONS - Google Patents

MOLECULES OF HDV NUCLEIC ACIDS, THEIR FRAGMENTS AND APPLICATIONS

Info

Publication number
ATE557091T1
ATE557091T1 AT10005982T AT10005982T ATE557091T1 AT E557091 T1 ATE557091 T1 AT E557091T1 AT 10005982 T AT10005982 T AT 10005982T AT 10005982 T AT10005982 T AT 10005982T AT E557091 T1 ATE557091 T1 AT E557091T1
Authority
AT
Austria
Prior art keywords
hdv
fragments
iii
genome
nucleic acids
Prior art date
Application number
AT10005982T
Other languages
German (de)
Inventor
Paul Deny
Nadjia Radjef
Patricia Huc-Anais
Original Assignee
Assist Publ Hopitaux De Paris
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Assist Publ Hopitaux De Paris filed Critical Assist Publ Hopitaux De Paris
Application granted granted Critical
Publication of ATE557091T1 publication Critical patent/ATE557091T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/10011—Arenaviridae
    • C12N2760/10111—Deltavirus, e.g. hepatitis delta virus
    • C12N2760/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/826—Viruses

Abstract

Isolated nucleic acids (I) for hepatitis D virus (HDV) are new. Isolated nucleic acids (I) for hepatitis D virus (HDV) comprising: (i) the genome of a HDV that, at the molecular level over the entire genome, has a divergence or genetic distance of at least 20% with respect to HDV of genotypes I-III; (ii) the genome of a HDV that, at the molecular level, has a divergence or genetic distance of at least 25% with respect to HDV of genotypes I-III over the 889-1289 region (R0); (iii) the complete genomes of the isolates or variants dFr-45, -47, -73, -910, -48, or -664; or (iv) a genome with a divergence or genetic distance less than 15% with respect to (iii). Independent claims are also included for: (1) specific fragments of (I); (2) detecting the specified HDV variants by hybridization and/or amplification; (3) detecting and genotyping HDV; (4) recombinant vectors, particularly plasmids, containing (I) or their fragments; (5) cells transformed with (I) or its fragments; (6) translation products (II) encoded by RNA of the specified variants; and (7) proteins encoded by (I), or its fragments, and their peptide fragments.
AT10005982T 2001-09-24 2002-09-23 MOLECULES OF HDV NUCLEIC ACIDS, THEIR FRAGMENTS AND APPLICATIONS ATE557091T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0112285A FR2830019B1 (en) 2001-09-24 2001-09-24 NUCLEIC ACID MOLECULES OF HDV, THEIR FRAGMENTS AND THEIR APLLICATIONS

Publications (1)

Publication Number Publication Date
ATE557091T1 true ATE557091T1 (en) 2012-05-15

Family

ID=8867559

Family Applications (2)

Application Number Title Priority Date Filing Date
AT10005982T ATE557091T1 (en) 2001-09-24 2002-09-23 MOLECULES OF HDV NUCLEIC ACIDS, THEIR FRAGMENTS AND APPLICATIONS
AT02781380T ATE476511T1 (en) 2001-09-24 2002-09-23 NUCLEIC ACIDS OF HDV, THEIR FRAGMENTS AND THEIR USES

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT02781380T ATE476511T1 (en) 2001-09-24 2002-09-23 NUCLEIC ACIDS OF HDV, THEIR FRAGMENTS AND THEIR USES

Country Status (11)

Country Link
US (2) US7351570B2 (en)
EP (2) EP2343374B1 (en)
AT (2) ATE557091T1 (en)
AU (1) AU2002349094A1 (en)
CY (1) CY1110861T1 (en)
DE (1) DE60237214D1 (en)
DK (1) DK1430134T3 (en)
ES (2) ES2350179T3 (en)
FR (1) FR2830019B1 (en)
PT (2) PT2343374E (en)
WO (1) WO2003027291A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1624076T3 (en) * 2004-08-06 2007-06-25 Assist Publ Hopitaux De Paris Quantitative detection of HDV by real-time RT-PCR
US9579377B2 (en) * 2011-06-14 2017-02-28 Globeimmune, Inc. Yeast-based compositions and methods for the treatment or prevention of hepatitis delta virus infection
EP2971188A1 (en) * 2013-03-15 2016-01-20 The U.S.A. as represented by the Secretary, Department of Health and Human Services Selective detection of hepatitis a, b, c, d, or e viruses or combinations thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3788902T3 (en) * 1986-06-17 2004-11-25 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Hepatitis delta diagnostics and vaccines, their manufacture and use.
US6844171B1 (en) * 1998-07-02 2005-01-18 President And Fellows Of Harvard College Oligomerization of hepatitis delta antigen

Also Published As

Publication number Publication date
WO2003027291A2 (en) 2003-04-03
ATE476511T1 (en) 2010-08-15
AU2002349094A1 (en) 2003-04-07
EP1430134A2 (en) 2004-06-23
US7351570B2 (en) 2008-04-01
ES2387604T3 (en) 2012-10-31
PT2343374E (en) 2012-08-08
PT1430134E (en) 2010-11-10
CY1110861T1 (en) 2015-06-10
EP2343374A1 (en) 2011-07-13
US8906619B2 (en) 2014-12-09
DK1430134T3 (en) 2010-11-22
EP1430134B1 (en) 2010-08-04
FR2830019A1 (en) 2003-03-28
FR2830019B1 (en) 2005-01-07
US20080187933A1 (en) 2008-08-07
EP2343374B1 (en) 2012-05-09
WO2003027291A3 (en) 2004-02-19
US20050107587A1 (en) 2005-05-19
ES2350179T3 (en) 2011-01-19
DE60237214D1 (en) 2010-09-16

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