ATE557091T1 - MOLECULES OF HDV NUCLEIC ACIDS, THEIR FRAGMENTS AND APPLICATIONS - Google Patents
MOLECULES OF HDV NUCLEIC ACIDS, THEIR FRAGMENTS AND APPLICATIONSInfo
- Publication number
- ATE557091T1 ATE557091T1 AT10005982T AT10005982T ATE557091T1 AT E557091 T1 ATE557091 T1 AT E557091T1 AT 10005982 T AT10005982 T AT 10005982T AT 10005982 T AT10005982 T AT 10005982T AT E557091 T1 ATE557091 T1 AT E557091T1
- Authority
- AT
- Austria
- Prior art keywords
- hdv
- fragments
- iii
- genome
- nucleic acids
- Prior art date
Links
- 239000012634 fragment Substances 0.000 title abstract 5
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- -1 HDV NUCLEIC ACIDS Chemical class 0.000 title 1
- 208000037262 Hepatitis delta Diseases 0.000 abstract 10
- 241000724709 Hepatitis delta virus Species 0.000 abstract 10
- 230000002068 genetic effect Effects 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 108010033276 Peptide Fragments Proteins 0.000 abstract 1
- 102000007079 Peptide Fragments Human genes 0.000 abstract 1
- 230000003321 amplification Effects 0.000 abstract 1
- 238000003205 genotyping method Methods 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/10011—Arenaviridae
- C12N2760/10111—Deltavirus, e.g. hepatitis delta virus
- C12N2760/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/826—Viruses
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Communicable Diseases (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pyrane Compounds (AREA)
Abstract
Isolated nucleic acids (I) for hepatitis D virus (HDV) are new. Isolated nucleic acids (I) for hepatitis D virus (HDV) comprising: (i) the genome of a HDV that, at the molecular level over the entire genome, has a divergence or genetic distance of at least 20% with respect to HDV of genotypes I-III; (ii) the genome of a HDV that, at the molecular level, has a divergence or genetic distance of at least 25% with respect to HDV of genotypes I-III over the 889-1289 region (R0); (iii) the complete genomes of the isolates or variants dFr-45, -47, -73, -910, -48, or -664; or (iv) a genome with a divergence or genetic distance less than 15% with respect to (iii). Independent claims are also included for: (1) specific fragments of (I); (2) detecting the specified HDV variants by hybridization and/or amplification; (3) detecting and genotyping HDV; (4) recombinant vectors, particularly plasmids, containing (I) or their fragments; (5) cells transformed with (I) or its fragments; (6) translation products (II) encoded by RNA of the specified variants; and (7) proteins encoded by (I), or its fragments, and their peptide fragments.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0112285A FR2830019B1 (en) | 2001-09-24 | 2001-09-24 | NUCLEIC ACID MOLECULES OF HDV, THEIR FRAGMENTS AND THEIR APLLICATIONS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE557091T1 true ATE557091T1 (en) | 2012-05-15 |
Family
ID=8867559
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02781380T ATE476511T1 (en) | 2001-09-24 | 2002-09-23 | NUCLEIC ACIDS OF HDV, THEIR FRAGMENTS AND THEIR USES |
| AT10005982T ATE557091T1 (en) | 2001-09-24 | 2002-09-23 | MOLECULES OF HDV NUCLEIC ACIDS, THEIR FRAGMENTS AND APPLICATIONS |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02781380T ATE476511T1 (en) | 2001-09-24 | 2002-09-23 | NUCLEIC ACIDS OF HDV, THEIR FRAGMENTS AND THEIR USES |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7351570B2 (en) |
| EP (2) | EP2343374B1 (en) |
| AT (2) | ATE476511T1 (en) |
| AU (1) | AU2002349094A1 (en) |
| CY (1) | CY1110861T1 (en) |
| DE (1) | DE60237214D1 (en) |
| DK (1) | DK1430134T3 (en) |
| ES (2) | ES2350179T3 (en) |
| FR (1) | FR2830019B1 (en) |
| PT (2) | PT2343374E (en) |
| WO (1) | WO2003027291A2 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1624076T1 (en) * | 2004-08-06 | 2007-10-31 | Assist Publ Hopitaux De Paris | Quantitative detection of HDV by real-time RT-PCR |
| ES2671381T3 (en) | 2011-06-14 | 2018-06-06 | Globeimmune, Inc. | Immunotherapeutic compositions for the treatment or prevention of hepatitis delta virus infection |
| WO2014144578A1 (en) * | 2013-03-15 | 2014-09-18 | The Usa, As Represented By The Secretary, Department Of Health And Human Services | Selective detection of hepatitis a, b, c, d, or e viruses or combinations thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2061500T5 (en) * | 1986-06-17 | 2003-05-16 | Chiron Corp | DIAGNOSIS AND VACCINES OF DELTA HEPATITIS, ITS PREPARATION AND USE. |
| US6844171B1 (en) * | 1998-07-02 | 2005-01-18 | President And Fellows Of Harvard College | Oligomerization of hepatitis delta antigen |
-
2001
- 2001-09-24 FR FR0112285A patent/FR2830019B1/en not_active Expired - Lifetime
-
2002
- 2002-09-23 US US10/489,864 patent/US7351570B2/en not_active Expired - Fee Related
- 2002-09-23 PT PT10005982T patent/PT2343374E/en unknown
- 2002-09-23 EP EP10005982A patent/EP2343374B1/en not_active Expired - Lifetime
- 2002-09-23 DK DK02781380.7T patent/DK1430134T3/en active
- 2002-09-23 AU AU2002349094A patent/AU2002349094A1/en not_active Abandoned
- 2002-09-23 DE DE60237214T patent/DE60237214D1/en not_active Expired - Lifetime
- 2002-09-23 PT PT02781380T patent/PT1430134E/en unknown
- 2002-09-23 AT AT02781380T patent/ATE476511T1/en active
- 2002-09-23 WO PCT/FR2002/003239 patent/WO2003027291A2/en not_active Application Discontinuation
- 2002-09-23 EP EP02781380A patent/EP1430134B1/en not_active Expired - Lifetime
- 2002-09-23 ES ES02781380T patent/ES2350179T3/en not_active Expired - Lifetime
- 2002-09-23 AT AT10005982T patent/ATE557091T1/en active
- 2002-09-23 ES ES10005982T patent/ES2387604T3/en not_active Expired - Lifetime
-
2008
- 2008-02-01 US US12/024,243 patent/US8906619B2/en active Active
-
2010
- 2010-10-25 CY CY20101100959T patent/CY1110861T1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1430134B1 (en) | 2010-08-04 |
| WO2003027291A2 (en) | 2003-04-03 |
| FR2830019A1 (en) | 2003-03-28 |
| ATE476511T1 (en) | 2010-08-15 |
| CY1110861T1 (en) | 2015-06-10 |
| PT1430134E (en) | 2010-11-10 |
| AU2002349094A1 (en) | 2003-04-07 |
| DK1430134T3 (en) | 2010-11-22 |
| ES2387604T3 (en) | 2012-10-31 |
| US20050107587A1 (en) | 2005-05-19 |
| PT2343374E (en) | 2012-08-08 |
| US8906619B2 (en) | 2014-12-09 |
| DE60237214D1 (en) | 2010-09-16 |
| US7351570B2 (en) | 2008-04-01 |
| WO2003027291A3 (en) | 2004-02-19 |
| ES2350179T3 (en) | 2011-01-19 |
| EP1430134A2 (en) | 2004-06-23 |
| FR2830019B1 (en) | 2005-01-07 |
| US20080187933A1 (en) | 2008-08-07 |
| EP2343374B1 (en) | 2012-05-09 |
| EP2343374A1 (en) | 2011-07-13 |
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