ATE551999T1 - P-glycoprotein-hemmer mit octiloniumbromid als wirkstoff - Google Patents

P-glycoprotein-hemmer mit octiloniumbromid als wirkstoff

Info

Publication number
ATE551999T1
ATE551999T1 AT03741600T AT03741600T ATE551999T1 AT E551999 T1 ATE551999 T1 AT E551999T1 AT 03741600 T AT03741600 T AT 03741600T AT 03741600 T AT03741600 T AT 03741600T AT E551999 T1 ATE551999 T1 AT E551999T1
Authority
AT
Austria
Prior art keywords
bromide
glycoprotein inhibitor
octilonium
active ingredient
drugs
Prior art date
Application number
AT03741600T
Other languages
English (en)
Inventor
Hesson Chung
Seo-Young Jeong
Ick-Chan Kwon
Yeong-Taek Park
In-Hyun Lee
Soon-Hong Yuk
Original Assignee
Daehwa Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daehwa Pharm Co Ltd filed Critical Daehwa Pharm Co Ltd
Application granted granted Critical
Publication of ATE551999T1 publication Critical patent/ATE551999T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT03741600T 2002-07-20 2003-07-21 P-glycoprotein-hemmer mit octiloniumbromid als wirkstoff ATE551999T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2002-0042794A KR100503889B1 (ko) 2002-07-20 2002-07-20 옥틸로늄 브로마이드를 함유하는 항암제 흡수 증진제
PCT/KR2003/001441 WO2004009073A1 (en) 2002-07-20 2003-07-21 P-glycoprotein inhibitor comprising octilonium bromide as an effective ingredient

Publications (1)

Publication Number Publication Date
ATE551999T1 true ATE551999T1 (de) 2012-04-15

Family

ID=36611883

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03741600T ATE551999T1 (de) 2002-07-20 2003-07-21 P-glycoprotein-hemmer mit octiloniumbromid als wirkstoff

Country Status (6)

Country Link
US (2) US20060141033A1 (de)
EP (1) EP1545495B1 (de)
KR (1) KR100503889B1 (de)
AT (1) ATE551999T1 (de)
AU (1) AU2003281468A1 (de)
WO (1) WO2004009073A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101187477B1 (ko) 2003-09-26 2012-10-02 소니 컴퓨터 엔터테인먼트 인코포레이티드 휴대형 전자장치
WO2011024028A1 (en) * 2009-08-24 2011-03-03 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Direct compression tablets of otilonium
AU2011268303A1 (en) 2010-06-16 2013-01-24 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Compositions and methods for the treatment of addiction, psychiatric disorders, and neurodegenerative disease
WO2018165649A1 (en) 2017-03-10 2018-09-13 Embera Neurotherapeutics, Inc. Pharmaceutical compositions and uses thereof
US11865093B2 (en) 2017-07-14 2024-01-09 University Of Massachusetts Methods and compositions for treating inflammation
KR102203334B1 (ko) * 2019-04-12 2021-01-15 성균관대학교산학협력단 피모자이드의 항암제 병용요법
CN114377003B (zh) * 2020-10-16 2023-09-15 中国科学院上海药物研究所 奥替溴铵在抗肿瘤中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1216283B (it) * 1986-11-04 1990-02-22 Menarini Sas Utilizzazione di ottilonio bromuro (dci) per applicazione topica nel tratto gastro-intestinale e relativa formulazione farmaceutica appropriata per tale uso.
US5968972A (en) * 1995-10-26 1999-10-19 Baker Norton Pharmaceuticals, Inc. Method for increasing the oral bioactivity of pharmaceutical agents
US5756475A (en) * 1996-01-31 1998-05-26 Nisshin Flour Milling Co., Ltd. Isoprene derivatives
GB9717576D0 (en) * 1997-08-19 1997-10-22 Xenova Ltd Pharmaceutical compounds
GB9721352D0 (en) * 1997-10-08 1997-12-10 Medinnova Sf Resistance modifying agent
KR20020013174A (ko) * 2000-08-11 2002-02-20 민경윤 경구 흡수율이 낮은 약물의 흡수율을 증가시키기 위한경구용 조성물
AU2003220523A1 (en) * 2002-03-27 2003-10-13 Massachusetts Institute Of Technology Platelet-activating factor antagonists as analgesic, anti-inflammatory, uterine contraction inhibiting, and anti-tumor agents

Also Published As

Publication number Publication date
KR100503889B1 (ko) 2005-07-26
WO2004009073A1 (en) 2004-01-29
EP1545495A1 (de) 2005-06-29
US20100029755A1 (en) 2010-02-04
US20060141033A1 (en) 2006-06-29
KR20040009018A (ko) 2004-01-31
EP1545495A4 (de) 2007-01-24
EP1545495B1 (de) 2012-04-04
AU2003281468A1 (en) 2004-02-09

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ATE551999T1 (de) P-glycoprotein-hemmer mit octiloniumbromid als wirkstoff
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