ATE549349T1 - HYBRID PROTEINS OF PARIETARIA MAJOR ALLERGENS AND THEIR USES - Google Patents

HYBRID PROTEINS OF PARIETARIA MAJOR ALLERGENS AND THEIR USES

Info

Publication number
ATE549349T1
ATE549349T1 AT10171705T AT10171705T ATE549349T1 AT E549349 T1 ATE549349 T1 AT E549349T1 AT 10171705 T AT10171705 T AT 10171705T AT 10171705 T AT10171705 T AT 10171705T AT E549349 T1 ATE549349 T1 AT E549349T1
Authority
AT
Austria
Prior art keywords
hybrid proteins
parietaria
major allergens
par
allergens
Prior art date
Application number
AT10171705T
Other languages
German (de)
Inventor
Giovanni Mistrello
Stefania Zanotta
Daniela Roncarolo
Paolo Falagiani
Original Assignee
Lofarma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lofarma Spa filed Critical Lofarma Spa
Application granted granted Critical
Publication of ATE549349T1 publication Critical patent/ATE549349T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

There are disclosed hybrid proteins consisting of mutated sequences of Par j 1 and Par j 2 allergens linked to each other either directly or by interposition of a linker, nucleic acid molecules encoding for them, pharmaceutical compositions containing the same, and their use in the immunotherapy of allergic diseases caused by pollen of plants from Parietaria judaica species.
AT10171705T 2009-08-04 2010-08-03 HYBRID PROTEINS OF PARIETARIA MAJOR ALLERGENS AND THEIR USES ATE549349T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI2009A001411A IT1395735B1 (en) 2009-08-04 2009-08-04 HYBRID PROTEIN HYPOALLERGENIC AND ITS USES

Publications (1)

Publication Number Publication Date
ATE549349T1 true ATE549349T1 (en) 2012-03-15

Family

ID=41503721

Family Applications (1)

Application Number Title Priority Date Filing Date
AT10171705T ATE549349T1 (en) 2009-08-04 2010-08-03 HYBRID PROTEINS OF PARIETARIA MAJOR ALLERGENS AND THEIR USES

Country Status (5)

Country Link
EP (1) EP2281836B9 (en)
AT (1) ATE549349T1 (en)
ES (1) ES2384231T3 (en)
IT (1) IT1395735B1 (en)
PT (1) PT2281836E (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1318690B1 (en) * 2000-09-12 2003-08-27 Consiglio Nazionale Ricerche VARIATIONS OF THE ALLERGEN PAR J 2 OF PARIETARIA JUDAICA.
ITRM20030247A1 (en) * 2003-05-20 2004-11-21 Bonura Angela HYPOALLERGENIC VARIANTS OF MAJOR ALLERGENS
ITRM20040103A1 (en) * 2004-02-27 2004-05-27 Consiglio Nazionale Ricerche MELTING PROTEINS INCLUDING ALLERGENS OF THE NS-LTPS FAMILY, THEIR USES AND PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM.
ITMI20050669A1 (en) * 2005-04-15 2006-10-16 Lofarma Spa HYPOALLERGENIC VARIATIONS OF ALLERGENES MORE PAR J 1 OF POLLUTARES OF PARIATARIA JUDAICA
ES2307381B1 (en) * 2006-04-12 2009-10-23 Bial Industrial Farmaceutica S.A. HYPOALLERGENIC CHEMICAL PROTEINS BELONGING TO THE FAMILY OF TRANSPORTERS OF JUDAICA PARIETARY LIPIDS USED FOR THE TREATMENT OF ALLERGIES.

Also Published As

Publication number Publication date
ES2384231T3 (en) 2012-07-02
ITMI20091411A1 (en) 2011-02-05
PT2281836E (en) 2012-06-06
EP2281836B1 (en) 2012-03-14
EP2281836B9 (en) 2012-09-26
EP2281836A1 (en) 2011-02-09
IT1395735B1 (en) 2012-10-19

Similar Documents

Publication Publication Date Title
CY1122691T1 (en) SERUM ALBUMIN-BINDING PROTEINS
CO2020001113A2 (en) Interleukin 21 Muteins and Treatment Methods
HRP20201815T1 (en) Nucleic acids for treatment of allergies
BR112012020705A2 (en) axmi221z, axmi222z, axmi224z, and axmi225z delta endotoxin genes and methods for their use.
CO6341638A2 (en) AXMI-115, AXMI-113, AXMI-005, AXMI-163 AND AXMI-184: INSECTED PROTEINS AND METHODS FOR USE
BR112014001909A2 (en) axmi270 toxin gene and methods for its use
BR112013028407A2 (en) "amino acid sequences directed to the il-17a, il-17f and / or il17-a / f polypeptides comprising them, their uses, polypeptides, and pharmaceutical composition".
BR112015014751A2 (en) human anti-tau antibodies
BR112014022166A2 (en) delta-endotoxin gene axmi345 and methods for its use
BRPI0713000A8 (en) SINGLE CHAIN MULTIESPECIFIC BINDING PROTEIN, PHARMACEUTICAL COMPOSITION AND USE OF SAID SINGLE CHAIN MULTIESPECIFIC BINDING PROTEIN
CA2865594C (en) Human binding molecules capable of binding to and neutralizing influenza b viruses and uses thereof
BR112012020921A2 (en) delta-endotoxin genes axmi218, axmi219, axmi220, axmi226, axmi227, axmi228, axmi229, axmi230 and axmi231 and methods for their use
MX357678B (en) Tdp-43 specific binding molecules.
EP3797583A3 (en) Methods and compositions for gene expression in plants
MX2009004243A (en) Novel h5 proteins, nucleic acid molecules and vectors encoding for those, and their medicinal use.
BR112014001978A2 (en) axmi205 variant proteins and methods for using them
AR079114A1 (en) ANTI-ORAI1 ANTIGEN LINK PROTEINS AND USES OF THE SAME
EA201491643A1 (en) IDENTIFICATION OF CANAL-OPSIN-2 (CHOP2) MUTATIONS AND APPLICATIONS
BR112014022034A2 (en) bacillus thuringiensis toxin axmi335 gene and methods for its use
BR112014023063A2 (en) antibodies that neutralize rsv, mpv and pvm and their uses
BR112016012306A2 (en) proline rich peptides for protection against s. pneumoniae
MX2020012569A (en) Novel immunotherapeutic molecules and uses thereof.
ATE549349T1 (en) HYBRID PROTEINS OF PARIETARIA MAJOR ALLERGENS AND THEIR USES
UY35345A (en) Manipulation of Self-incompatibility in Plants
IL177698A0 (en) Fusion proeins comprising modified allergens of the ns-ltps family, use thereof and pharmaceutical compositions comprising the same