ATE544472T1 - Kalziumphosphat-nanopartikel als farbstoffträger für die photodynamische therapie - Google Patents

Kalziumphosphat-nanopartikel als farbstoffträger für die photodynamische therapie

Info

Publication number
ATE544472T1
ATE544472T1 AT08022155T AT08022155T ATE544472T1 AT E544472 T1 ATE544472 T1 AT E544472T1 AT 08022155 T AT08022155 T AT 08022155T AT 08022155 T AT08022155 T AT 08022155T AT E544472 T1 ATE544472 T1 AT E544472T1
Authority
AT
Austria
Prior art keywords
calcium phosphate
nanoparticle formulations
photosensitizer
preferred
photosensitizers
Prior art date
Application number
AT08022155T
Other languages
English (en)
Inventor
Volker Albrecht
Burkhard Gitter
Susanna Graefe
Arno Wiehe
Matthias Epple
Janine Schwiertz
Ganesan Kathinvel
Original Assignee
Biolitec Ag
Univ Duisburg Essen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biolitec Ag, Univ Duisburg Essen filed Critical Biolitec Ag
Application granted granted Critical
Publication of ATE544472T1 publication Critical patent/ATE544472T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5115—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0089—Particulate, powder, adsorbate, bead, sphere
    • A61K49/0091—Microparticle, microcapsule, microbubble, microsphere, microbead, i.e. having a size or diameter higher or equal to 1 micrometer
    • A61K49/0093—Nanoparticle, nanocapsule, nanobubble, nanosphere, nanobead, i.e. having a size or diameter smaller than 1 micrometer, e.g. polymeric nanoparticle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
AT08022155T 2008-12-19 2008-12-19 Kalziumphosphat-nanopartikel als farbstoffträger für die photodynamische therapie ATE544472T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08022155A EP2198885B1 (de) 2008-12-19 2008-12-19 Kalziumphosphat-Nanopartikel als Farbstoffträger für die photodynamische Therapie

Publications (1)

Publication Number Publication Date
ATE544472T1 true ATE544472T1 (de) 2012-02-15

Family

ID=40677783

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08022155T ATE544472T1 (de) 2008-12-19 2008-12-19 Kalziumphosphat-nanopartikel als farbstoffträger für die photodynamische therapie

Country Status (7)

Country Link
US (1) US8956648B2 (de)
EP (1) EP2198885B1 (de)
JP (1) JP5138818B2 (de)
CN (1) CN102256622B (de)
AT (1) ATE544472T1 (de)
ES (1) ES2381022T3 (de)
WO (1) WO2010078941A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102010025476B4 (de) * 2010-06-29 2014-04-30 Universität des Saarlandes Komplexe mit Polystyrolsulfonat
WO2012145801A1 (en) * 2011-04-29 2012-11-01 Jagat Rakesh Kanwar Nanoparticle
WO2013009701A2 (en) 2011-07-08 2013-01-17 The University Of North Carolina At Chapel Hill Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders
RU2015137815A (ru) * 2013-02-05 2017-03-13 1ГЛОУБ ХЕЛТ ИНСТИТЬЮТ ЭлЭлСи Биодеградируемые и клинически совместимые наночастицы в качестве носителей для доставки лекарственного средства
CN103202316A (zh) * 2013-03-06 2013-07-17 安徽大学 一种具有抑菌功能的吩噻嗪衍生物/银纳米复合材料及其制备方法
IN2013DE02943A (de) * 2013-10-04 2015-04-10 Sanjay Banerji
KR101567717B1 (ko) 2014-07-24 2015-11-10 가톨릭대학교 산학협력단 칼슘 이온 및 친수성 음이온성 광민감제를 이용한 나노복합체의 제조방법 및 상기 나노복합체를 이용한 약물전달체
KR101622031B1 (ko) * 2014-07-25 2016-05-19 경희대학교 산학협력단 광감작제 담지 탄산칼슘 복합 나노입자, 이의 제조방법 및 이를 포함하는 초음파 조영 및 광역학 치료용 조성물
EP3229783A4 (de) * 2014-12-09 2018-08-08 Belmont University Pharmazeutische halbfeste gele mit eingeschlossenen calciumphosphatnanopartikeln
WO2017096342A1 (en) 2015-12-03 2017-06-08 Amrita Vishwa Vidyapeetham Radio-wave responsive doped nanoparticles for image-guided therapeutics
CN105954268B (zh) * 2016-04-22 2019-01-11 华南师范大学 一种基于四氧化三铁纳米簇催化信号放大的可视化检测传感器及其构建与应用
CN109415210B (zh) * 2016-06-30 2023-04-21 株式会社索夫塞拉 磷酸钙烧结体粒子及其制造方法
WO2018106931A1 (en) 2016-12-07 2018-06-14 Progenity Inc. Gastrointestinal tract detection methods, devices and systems
EP3638367A4 (de) 2017-08-02 2021-07-21 The University of Chicago Nanoskalige metallorganische schichten und metallorganische nanoplatten für die röntgenstrahlinduzierte photodynamische therapie, strahlentherapie, dynamische strahlentherapie, chemotherapie, immuntherapie und eine beliebige kombination davon
EP3789760A1 (de) * 2019-09-05 2021-03-10 PreSens Precision Sensing GmbH Kohlendioxidgassensor
CN111973573B (zh) * 2020-08-04 2022-10-18 中山大学附属第七医院(深圳) 一种磷酸钙纳米颗粒及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7455858B2 (en) 2002-05-16 2008-11-25 Qlt Inc. Compositions and methods for delivery of photosensitive drugs
US20090246127A1 (en) * 2004-12-17 2009-10-01 Koninklijke Philips Electronics, N.V. Targeting agents for molecular imaging
US20070218049A1 (en) 2006-02-02 2007-09-20 Wei Chen Nanoparticle based photodynamic therapy and methods of making and using same
WO2006093891A2 (en) * 2005-02-28 2006-09-08 The General Hospital Corporation Photosensitizers for targeted photodynamic therapy
DE102005016873A1 (de) * 2005-04-12 2006-10-19 Magforce Nanotechnologies Ag Nanopartikel-Wirstoff-Konjugate
US20080241256A1 (en) 2007-03-30 2008-10-02 Liisa Kuhn Targeted active agent delivery system based on calcium phosphate nanoparticles
WO2009099136A1 (ja) * 2008-02-07 2009-08-13 Kuraray Medical Inc. リン酸カルシウム組成物及びその製造方法

Also Published As

Publication number Publication date
CN102256622A (zh) 2011-11-23
JP2012512817A (ja) 2012-06-07
ES2381022T3 (es) 2012-05-22
US8956648B2 (en) 2015-02-17
EP2198885A1 (de) 2010-06-23
WO2010078941A1 (en) 2010-07-15
US20110257586A1 (en) 2011-10-20
JP5138818B2 (ja) 2013-02-06
CN102256622B (zh) 2014-10-29
EP2198885B1 (de) 2012-02-08

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