ATE534390T1 - Verwendung von levocabastin zur modulierung der erzeugung von proinflammatorischen zytokinen - Google Patents

Verwendung von levocabastin zur modulierung der erzeugung von proinflammatorischen zytokinen

Info

Publication number
ATE534390T1
ATE534390T1 AT08852672T AT08852672T ATE534390T1 AT E534390 T1 ATE534390 T1 AT E534390T1 AT 08852672 T AT08852672 T AT 08852672T AT 08852672 T AT08852672 T AT 08852672T AT E534390 T1 ATE534390 T1 AT E534390T1
Authority
AT
Austria
Prior art keywords
levocabastine
proinflammatory cytokines
generation
inflammatory
modulate
Prior art date
Application number
AT08852672T
Other languages
English (en)
Inventor
Claudio Bucolo
Keith Ward
Jinzhong Zhang
Original Assignee
Bausch & Lomb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch & Lomb filed Critical Bausch & Lomb
Application granted granted Critical
Publication of ATE534390T1 publication Critical patent/ATE534390T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT08852672T 2007-11-19 2008-10-27 Verwendung von levocabastin zur modulierung der erzeugung von proinflammatorischen zytokinen ATE534390T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98891307P 2007-11-19 2007-11-19
PCT/US2008/081328 WO2009067317A2 (en) 2007-11-19 2008-10-27 Use of levocabastine for modulating generation of pro- inflammatory cytokines

Publications (1)

Publication Number Publication Date
ATE534390T1 true ATE534390T1 (de) 2011-12-15

Family

ID=40430145

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08852672T ATE534390T1 (de) 2007-11-19 2008-10-27 Verwendung von levocabastin zur modulierung der erzeugung von proinflammatorischen zytokinen

Country Status (3)

Country Link
EP (1) EP2222299B1 (de)
AT (1) ATE534390T1 (de)
WO (1) WO2009067317A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010129351A1 (en) 2009-04-28 2010-11-11 Schepens Eye Research Institute Method to identify and treat age-related macular degeneration
WO2013061269A1 (en) * 2011-10-26 2013-05-02 Micro Labs Limited Combinations of loteprednol and olopatadine for the treatment of ocular allergies
WO2020081075A1 (en) * 2018-10-17 2020-04-23 Google Llc Processing fundus camera images using machine learning models trained using other modalities
EP4440555A4 (de) * 2021-11-30 2025-12-03 Univ Leland Stanford Junior Neuroprotektive mittel zur verwendung bei der behandlung von optischen neuropathien
CN117357526A (zh) * 2023-10-07 2024-01-09 侯玉才 一种有抗过敏退热作用的消炎药

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192780A (en) * 1989-12-18 1993-03-09 Alcon Laboratories, Inc. Methods using antiallergics and antihistamines
WO1997001337A1 (en) * 1995-06-29 1997-01-16 Mcneil-Ppc, Inc. The combination of topical nasal antihistamines and topical nasal steroids
US5648358A (en) * 1996-03-05 1997-07-15 Mitra; Sekhar Compositions and methods for treating respiratory disorders
US6239113B1 (en) * 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
CN1376066A (zh) * 1999-11-18 2002-10-23 爱尔康公司 H1拮抗剂和安全类固醇的治疗眼病的用途
DE10007203A1 (de) * 2000-02-17 2001-08-23 Asta Medica Ag Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis
US6827946B2 (en) * 2001-12-05 2004-12-07 Collegium Pharmaceutical, Inc. Compositions containing both sedative and non-sedative antihistamines

Also Published As

Publication number Publication date
EP2222299A2 (de) 2010-09-01
WO2009067317A2 (en) 2009-05-28
EP2222299B1 (de) 2011-11-23
WO2009067317A3 (en) 2009-08-06

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