ATE533788T1 - Antikörper gegen cd44vra und methoden zu ihrer verwendung - Google Patents

Antikörper gegen cd44vra und methoden zu ihrer verwendung

Info

Publication number
ATE533788T1
ATE533788T1 AT04744979T AT04744979T ATE533788T1 AT E533788 T1 ATE533788 T1 AT E533788T1 AT 04744979 T AT04744979 T AT 04744979T AT 04744979 T AT04744979 T AT 04744979T AT E533788 T1 ATE533788 T1 AT E533788T1
Authority
AT
Austria
Prior art keywords
antibodies
specific
methods
variant
cd44vra
Prior art date
Application number
AT04744979T
Other languages
English (en)
Inventor
David Naor
Itshak Golan
Original Assignee
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co filed Critical Yissum Res Dev Co
Application granted granted Critical
Publication of ATE533788T1 publication Critical patent/ATE533788T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2884—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD44
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70585—CD44

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT04744979T 2003-07-15 2004-07-15 Antikörper gegen cd44vra und methoden zu ihrer verwendung ATE533788T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48691903P 2003-07-15 2003-07-15
US49587603P 2003-08-19 2003-08-19
PCT/IL2004/000639 WO2005007700A1 (en) 2003-07-15 2004-07-15 Antibodies to cd44 vra and methods of use

Publications (1)

Publication Number Publication Date
ATE533788T1 true ATE533788T1 (de) 2011-12-15

Family

ID=34083397

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04744979T ATE533788T1 (de) 2003-07-15 2004-07-15 Antikörper gegen cd44vra und methoden zu ihrer verwendung

Country Status (5)

Country Link
EP (1) EP1646657B1 (de)
JP (1) JP2008500004A (de)
AT (1) ATE533788T1 (de)
CA (1) CA2532323A1 (de)
WO (1) WO2005007700A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7534605B2 (en) 1999-06-08 2009-05-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases
IL133647A0 (en) * 1999-06-08 2001-04-30 Yissum Res Dev Co Novel cd44 variant
EP1869170A4 (de) * 2005-02-24 2010-03-17 Scripps Research Inst Isolierte myeloid-ähnliche knochenmarkzellpopulationen und behandlungsverfahren damit
WO2010058396A1 (en) * 2008-11-19 2010-05-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. A cd44vra antibody and diagnostic and therapeutic methods using same
DE102013008687A1 (de) 2013-05-22 2014-11-27 Stefan Martin Hanstein Herstellung von wässrigen Reaktionslösungen auf der Basis von pflanzlichen Hydroxyzimtsäuren (Phenolsäuren/Phenylpropanoide/Phenylpropene) und Lignin für die Beschichtung von Düngergranulaten. Im Besonderen: Herstellung von entsprechenden Reaktionslösunge
EP2886126B1 (de) * 2013-12-23 2017-06-07 Exchange Imaging Technologies GmbH An CD44-bindende Peptide konjugierte Nanopartikel
KR102215384B1 (ko) * 2014-06-11 2021-02-15 (재) 스크립스코리아항체연구원 CD44v3 도메인 3 및 도메인 6 특이적 단일클론 항체 및 그 용도
DK3169343T3 (da) 2014-07-15 2020-06-22 Yissum Research And Development Company Of The Hebrew Univ Of Jerusalem Ltd Isolerede cd44-polypeptider og anvendelser heraf
CN116496398B (zh) * 2022-10-31 2023-10-31 南京元迈细胞生物科技有限公司 一种特异性结合CD44的v5外显子的抗体及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL133647A0 (en) * 1999-06-08 2001-04-30 Yissum Res Dev Co Novel cd44 variant
AU2002326112A1 (en) * 2001-08-09 2003-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem Cd44 variants carrying heparan sulfate chains and uses thereof
EP1490403A2 (de) * 2002-02-28 2004-12-29 YEDA RESEARCH AND DEVELOPMENT Co. LTD. Galectin-8 und funktionelle derivate als mittel zur bindung von cd44-glykoproteinen und anwendungsverfahren

Also Published As

Publication number Publication date
JP2008500004A (ja) 2008-01-10
EP1646657A1 (de) 2006-04-19
CA2532323A1 (en) 2005-01-27
WO2005007700A1 (en) 2005-01-27
EP1646657B1 (de) 2011-11-16

Similar Documents

Publication Publication Date Title
EA201100668A1 (ru) Способы продуцирования антител из плазматических клеток
WO2001098358A3 (en) Compositions for identification and isolation of stem cells
MA49823B1 (fr) Anticorps dirigés contre pd-l1
MX2007007484A (es) Anticuerpos dirigidos a angiopoyetina 2 y usos de los mismos.
Vergroesen et al. N-glycosylation site analysis of citrullinated antigen-specific B-cell receptors indicates alternative selection pathways during autoreactive B-cell development
ZA200703124B (en) System and method for production of antibodies in plant cell culture
MXPA05005925A (es) Anticuerpos dirigidos a la fosfolipasa a2 y sus usos.
WO2003052082A3 (en) Fusion partner cells and uses thereof
ZA200603731B (en) Plasmid system for multiple expression
CL2009000575A1 (es) Anticuerpos aislados anti-interleuquina 12 (anti il-12) de mamiferos, secuencia de nucleotidos, vector, celula y metodo de produccion, composicion y dispositivo medico que contienen, util en el diagnostico y tratamiento de condicones relacionadas con il-12.
SG155883A1 (en) Anti-cd3 antibodies and methods of use thereof
CL2007003649A1 (es) Un conjugado de molecula asociado a anticuerpo monoclonal humano anti-cd70; composicion que comprende al conjugado de molecula asociado a anticuerpo; metodo de inhibicion del crecimiento de celulas tumorales que expresan cd70.
EP2534257A4 (de) Verfahren zur identifikation und isolierung von zellen zur expression von polypeptiden
UA99701C2 (ru) Человеческое моноклональное антитело, которое специфически связывается с лигандом-1 запрограммированной гибели клеток (pd-l1)
SI1644484T1 (sl) Avtologne samo-toleranco inducirajoče celice monocitnega izvora in njihova uporaba v farmacevtskihpripravah
ATE533788T1 (de) Antikörper gegen cd44vra und methoden zu ihrer verwendung
Trier et al. Epitope specificity of anti-citrullinated protein antibodies
WO2001090151A3 (en) Human receptor proteins; related reagents and methods
ATE279443T1 (de) A3c6e2, ein monoklonaler antikörper spezifisch für den humanen stammzellfaktor (scf)-rezeptor
WO2002094853A3 (en) Antibodies specific for poly(ethylene glycol)
WO2012041332A3 (en) Genetic variations in the interleukin-6 receptor gene as predictors of the response to treatment
EA200800601A1 (ru) Связывающие fas антитела
DE50307968D1 (de) Antikörper zur isolierung und/oder identifizierung mesenchymaler stammzellen und verfahren zur isolierung und/oder identifizierung mesenchymaler stammzellen
ATE505535T1 (de) Verfahren zur herstellung stabiler b-lymphozyten
TW200740842A (en) Monoclonal antibodies, hybridoma cell lines, methods and kits for detecting phytase