ATE532866T1 - Peptiddeformylase als hilfsmittel zur entwicklung mykobakterien-spezifischer antisense- nukleinsäuremoleküle - Google Patents

Peptiddeformylase als hilfsmittel zur entwicklung mykobakterien-spezifischer antisense- nukleinsäuremoleküle

Info

Publication number
ATE532866T1
ATE532866T1 AT07804653T AT07804653T ATE532866T1 AT E532866 T1 ATE532866 T1 AT E532866T1 AT 07804653 T AT07804653 T AT 07804653T AT 07804653 T AT07804653 T AT 07804653T AT E532866 T1 ATE532866 T1 AT E532866T1
Authority
AT
Austria
Prior art keywords
peptide deformylase
mycobacteria
tool
development
nucleic acid
Prior art date
Application number
AT07804653T
Other languages
English (en)
Inventor
Rahul Saxena
Pradip Chakraborti
Original Assignee
Council Scient Ind Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council Scient Ind Res filed Critical Council Scient Ind Res
Application granted granted Critical
Publication of ATE532866T1 publication Critical patent/ATE532866T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01088—Peptide deformylase (3.5.1.88)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT07804653T 2006-08-02 2007-07-27 Peptiddeformylase als hilfsmittel zur entwicklung mykobakterien-spezifischer antisense- nukleinsäuremoleküle ATE532866T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1763DE2006 2006-08-02
PCT/IB2007/002144 WO2008015524A2 (en) 2006-08-02 2007-07-27 Peptide deformylase as a tool for development of mycobacteria specific antisense nucleic acid molecules

Publications (1)

Publication Number Publication Date
ATE532866T1 true ATE532866T1 (de) 2011-11-15

Family

ID=38997518

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07804653T ATE532866T1 (de) 2006-08-02 2007-07-27 Peptiddeformylase als hilfsmittel zur entwicklung mykobakterien-spezifischer antisense- nukleinsäuremoleküle

Country Status (9)

Country Link
US (3) US20080233103A1 (de)
EP (1) EP2046955B1 (de)
JP (1) JP5203366B2 (de)
CN (1) CN101541964B (de)
AT (1) ATE532866T1 (de)
AU (1) AU2007280137B9 (de)
CA (1) CA2658801C (de)
WO (1) WO2008015524A2 (de)
ZA (1) ZA200901273B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7608787B2 (ja) * 2020-11-02 2025-01-07 東ソー株式会社 組換えタンパク質の抽出試薬

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR028075A1 (es) * 2000-05-05 2003-04-23 Smithkline Beecham Corp Inhibidores de la peptido-desformilasa
JP2007505050A (ja) * 2003-09-12 2007-03-08 アルピダ エー／エス ペプチドデホルミラーゼ阻害剤としてのイソキサゾール類
WO2005037272A1 (en) * 2003-10-22 2005-04-28 Arpida A/S Benzimidazole derivatives and use thereof as peptide deformylase inhibitors
US20090093468A1 (en) * 2004-03-26 2009-04-09 Patrizia Cali Peptide Deformylase Inhibitors

Also Published As

Publication number Publication date
JP2010505389A (ja) 2010-02-25
ZA200901273B (en) 2010-06-30
WO2008015524A3 (en) 2008-07-24
JP5203366B2 (ja) 2013-06-05
EP2046955B1 (de) 2011-11-09
US8907076B2 (en) 2014-12-09
CN101541964A (zh) 2009-09-23
EP2046955A2 (de) 2009-04-15
AU2007280137A1 (en) 2008-02-07
AU2007280137B9 (en) 2013-05-30
US20080233103A1 (en) 2008-09-25
US20110263003A1 (en) 2011-10-27
CA2658801C (en) 2015-09-08
AU2007280137B2 (en) 2013-04-18
US8426580B2 (en) 2013-04-23
WO2008015524A2 (en) 2008-02-07
US20100273861A1 (en) 2010-10-28
CN101541964B (zh) 2011-09-28
CA2658801A1 (en) 2008-02-07

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