ATE528390T1 - PARATHYROID AND THYM TRANSPLANTATION IN PERSONS WITH DI GEORGE SYNDROME - Google Patents

PARATHYROID AND THYM TRANSPLANTATION IN PERSONS WITH DI GEORGE SYNDROME

Info

Publication number
ATE528390T1
ATE528390T1 AT06739260T AT06739260T ATE528390T1 AT E528390 T1 ATE528390 T1 AT E528390T1 AT 06739260 T AT06739260 T AT 06739260T AT 06739260 T AT06739260 T AT 06739260T AT E528390 T1 ATE528390 T1 AT E528390T1
Authority
AT
Austria
Prior art keywords
parathyroid
thym
transplantation
persons
implanting
Prior art date
Application number
AT06739260T
Other languages
German (de)
Inventor
M Louise Markert
Original Assignee
Univ Duke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Duke filed Critical Univ Duke
Application granted granted Critical
Publication of ATE528390T1 publication Critical patent/ATE528390T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/065—Thymocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/26—Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/40—Nucleotides, nucleosides or bases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A method of treating hypoparathyroidism in a human DiGeorge syndrome subject comprises (a) implanting thymus tissue into the subject in an amount effective to treat the DiGeorge syndrome; and (b) implanting, preferably concurrently implanting, parathyroid tissue into the subject in an amount effective to treat the hypoparathyroidism.
AT06739260T 2005-04-06 2006-03-22 PARATHYROID AND THYM TRANSPLANTATION IN PERSONS WITH DI GEORGE SYNDROME ATE528390T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66874505P 2005-04-06 2005-04-06
US70953405P 2005-08-19 2005-08-19
PCT/US2006/010387 WO2006107601A2 (en) 2005-04-06 2006-03-22 Parathyroid and thymus transplantation in digeorge syndrome subjects

Publications (1)

Publication Number Publication Date
ATE528390T1 true ATE528390T1 (en) 2011-10-15

Family

ID=37073935

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06739260T ATE528390T1 (en) 2005-04-06 2006-03-22 PARATHYROID AND THYM TRANSPLANTATION IN PERSONS WITH DI GEORGE SYNDROME

Country Status (4)

Country Link
US (1) US20090041854A1 (en)
EP (1) EP1866409B1 (en)
AT (1) ATE528390T1 (en)
WO (1) WO2006107601A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8353832B2 (en) * 2008-10-14 2013-01-15 Theraclion Systems and methods for ultrasound treatment of thyroid and parathyroid
JP5431831B2 (en) * 2009-08-21 2014-03-05 株式会社ディスコ Laser processing equipment
DE102011116280B4 (en) 2011-10-19 2013-05-29 Otto Bock Healthcare Gmbh Connection system and prosthesis system
JP7499178B2 (en) 2018-02-23 2024-06-13 デューク ユニバーシティ Cultured thymic tissue transplantation promotes donor-specific tolerance to allogeneic solid organ transplantation
WO2021034650A1 (en) * 2019-08-19 2021-02-25 Duke University & Medical Center Methods of determining the suitability of cultured thymus tissue for implantation into humans and associated methods of use
US11819520B2 (en) 2018-02-23 2023-11-21 Duke University Cultured thymus tissue transplantation promotes donor-specific tolerance to allogeneic solid organ transplants
GB2603310A (en) * 2019-08-05 2022-08-03 Univ Pittsburgh Commonwealth Sys Higher Education Autologous thymic tissue transplantation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0973888A1 (en) * 1997-02-06 2000-01-26 Human Genome Sciences, Inc. Dendritic cell-derived growth factor

Also Published As

Publication number Publication date
US20090041854A1 (en) 2009-02-12
EP1866409B1 (en) 2011-10-12
EP1866409A4 (en) 2010-01-06
WO2006107601A2 (en) 2006-10-12
WO2006107601A3 (en) 2007-03-15
EP1866409A2 (en) 2007-12-19

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Legal Events

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