ATE526989T1 - Photodynamische therapie mit chemolumineszenz und ligand-photosensibilisator-konjugat - Google Patents
Photodynamische therapie mit chemolumineszenz und ligand-photosensibilisator-konjugatInfo
- Publication number
- ATE526989T1 ATE526989T1 AT06728287T AT06728287T ATE526989T1 AT E526989 T1 ATE526989 T1 AT E526989T1 AT 06728287 T AT06728287 T AT 06728287T AT 06728287 T AT06728287 T AT 06728287T AT E526989 T1 ATE526989 T1 AT E526989T1
- Authority
- AT
- Austria
- Prior art keywords
- ligand
- chemoluminescence
- photodynamic therapy
- photosensitizer
- photosensitizer conjugate
- Prior art date
Links
- 239000003504 photosensitizing agent Substances 0.000 title abstract 2
- 238000002428 photodynamic therapy Methods 0.000 title 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000005081 chemiluminescent agent Substances 0.000 abstract 1
- 229910001882 dioxygen Inorganic materials 0.000 abstract 1
- 239000002596 immunotoxin Substances 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000003642 reactive oxygen metabolite Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/644—Transferrin, e.g. a lactoferrin or ovotransferrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Radiation-Therapy Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL168184A IL168184A (en) | 2005-04-21 | 2005-04-21 | Use of a ligand-photosensitizer conjugate in combination with a chemiluminescent agent in the manufacture of a medicament for photodynamic therapy |
| PCT/IL2006/000487 WO2006111971A2 (en) | 2005-04-21 | 2006-04-20 | Photodynamic therapy using chemiluminescence and a ligand-photosensitiser conjugate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE526989T1 true ATE526989T1 (de) | 2011-10-15 |
Family
ID=37115566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06728287T ATE526989T1 (de) | 2005-04-21 | 2006-04-20 | Photodynamische therapie mit chemolumineszenz und ligand-photosensibilisator-konjugat |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7772179B2 (de) |
| EP (2) | EP1874352B1 (de) |
| JP (1) | JP4981031B2 (de) |
| AT (1) | ATE526989T1 (de) |
| AU (1) | AU2006238428B2 (de) |
| CA (1) | CA2605617C (de) |
| ES (1) | ES2374437T3 (de) |
| IL (1) | IL168184A (de) |
| WO (1) | WO2006111971A2 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL168184A (en) * | 2005-04-21 | 2011-11-30 | Univ Ariel Res & Dev Co Ltd | Use of a ligand-photosensitizer conjugate in combination with a chemiluminescent agent in the manufacture of a medicament for photodynamic therapy |
| US9358292B2 (en) | 2007-04-08 | 2016-06-07 | Immunolight, Llc | Methods and systems for treating cell proliferation disorders |
| AU2016210665B2 (en) * | 2007-04-08 | 2017-12-07 | Immunolight, Llc | Methods and systems for treating cell proliferation disorders |
| WO2013009688A1 (en) | 2011-07-08 | 2013-01-17 | Bourke Frederic A | Phosphors and scintillators for light stimulation within a medium |
| CN102056625B (zh) * | 2008-04-04 | 2015-11-25 | 免疫之光有限责任公司 | 用于原位光生物调节的非侵入性系统和方法 |
| US8731655B2 (en) | 2009-05-12 | 2014-05-20 | Mallinckrodt Llc | Compounds containing acyclic N-N bonds for phototherapy |
| WO2010132554A2 (en) * | 2009-05-12 | 2010-11-18 | Mallinckrodt Inc. | Diaza heterocyclic compounds for phototherapy |
| US20130243741A1 (en) * | 2010-09-21 | 2013-09-19 | Kansas State University Research Foundation | Renilla/gaussia transfected cells as a light source for in-situ photodynamic therapy of cancer |
| CA2829755A1 (en) | 2011-03-23 | 2012-09-27 | Semorex Technologies Ltd. | Treatment of proliferative disorders with a chemiluminescent agent |
| US20140010760A1 (en) * | 2012-04-05 | 2014-01-09 | Brij P. Giri | Hypoxia-Targeted Polymeric Micelles For Cancer Therapy And Imaging |
| WO2014078768A1 (en) * | 2012-11-19 | 2014-05-22 | Troyer Deryl L | Leukocytes as delivery cells for imaging and disease therapy |
| US12121581B2 (en) * | 2018-06-21 | 2024-10-22 | Oslo Universitetssykehus Hf | Method of photodynamic therapy |
| CN115227814B (zh) * | 2021-03-08 | 2024-09-03 | 苏州大学 | 一种化学发光介导的纳米颗粒、自组装聚集体及其制备方法和应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4181650A (en) * | 1975-08-25 | 1980-01-01 | Maier Charles L Jr | Procedure for the assay of pharmacologically immunologically and biochemically active compounds in biological fluids |
| US4870002A (en) * | 1981-04-07 | 1989-09-26 | The United States Of America As Represented By The Secretary Of The Air Force | Method of prevention of oxidative injury to cells |
| US5094939A (en) * | 1988-07-19 | 1992-03-10 | Fujirebio, Inc. | Chemiluminescence assays using stabilized dioxetane derivatives |
| ATE115864T1 (de) * | 1990-05-30 | 1995-01-15 | Deutsches Krebsforsch | Polyethersubstituierte tumormittel. |
| US5622685A (en) * | 1990-05-30 | 1997-04-22 | Deutches Krebsforchunszentrum Stiftung Des Offentlichen Rechts | Polyether-substituted porphyrin anti-tumor agents |
| CA2056142A1 (en) * | 1990-11-27 | 1992-05-28 | Hirotomo Masuya | Pyridopyridazine compounds and their use |
| CA2069145C (en) * | 1991-05-22 | 2007-07-31 | Edwin F. Ullman | Assay method utilizing induced luminescence |
| US5257970A (en) | 1992-04-09 | 1993-11-02 | Health Research, Inc. | In situ photodynamic therapy |
| WO1994014956A1 (en) | 1992-12-23 | 1994-07-07 | Iowa State University Research Foundation, Inc. | Molecular flashlight |
| US6344050B1 (en) | 1998-12-21 | 2002-02-05 | Light Sciences Corporation | Use of pegylated photosensitizer conjugated with an antibody for treating abnormal tissue |
| GB0001455D0 (en) * | 2000-01-21 | 2000-03-15 | Scotia Holdings Plc | Porphyrins and related compounds |
| JP2004532245A (ja) | 2001-05-15 | 2004-10-21 | ページ ダブル フォーク | 癌を治療するための生体影響性化合物の標的送達 |
| IL168184A (en) * | 2005-04-21 | 2011-11-30 | Univ Ariel Res & Dev Co Ltd | Use of a ligand-photosensitizer conjugate in combination with a chemiluminescent agent in the manufacture of a medicament for photodynamic therapy |
-
2005
- 2005-04-21 IL IL168184A patent/IL168184A/en not_active IP Right Cessation
-
2006
- 2006-04-20 JP JP2008507266A patent/JP4981031B2/ja not_active Expired - Fee Related
- 2006-04-20 EP EP06728287A patent/EP1874352B1/de not_active Not-in-force
- 2006-04-20 AU AU2006238428A patent/AU2006238428B2/en not_active Ceased
- 2006-04-20 AT AT06728287T patent/ATE526989T1/de not_active IP Right Cessation
- 2006-04-20 US US11/918,905 patent/US7772179B2/en not_active Expired - Fee Related
- 2006-04-20 EP EP10181069A patent/EP2308508A1/de not_active Withdrawn
- 2006-04-20 WO PCT/IL2006/000487 patent/WO2006111971A2/en not_active Ceased
- 2006-04-20 ES ES06728287T patent/ES2374437T3/es active Active
- 2006-04-20 CA CA2605617A patent/CA2605617C/en not_active Expired - Fee Related
-
2010
- 2010-08-05 US US12/850,681 patent/US20100297762A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008536912A (ja) | 2008-09-11 |
| CA2605617C (en) | 2013-06-11 |
| ES2374437T3 (es) | 2012-02-16 |
| AU2006238428A2 (en) | 2006-10-26 |
| EP1874352B1 (de) | 2011-10-05 |
| IL168184A (en) | 2011-11-30 |
| AU2006238428A1 (en) | 2006-10-26 |
| EP1874352A2 (de) | 2008-01-09 |
| EP2308508A1 (de) | 2011-04-13 |
| US7772179B2 (en) | 2010-08-10 |
| AU2006238428B2 (en) | 2012-03-08 |
| WO2006111971A3 (en) | 2007-07-12 |
| JP4981031B2 (ja) | 2012-07-18 |
| US20090054306A1 (en) | 2009-02-26 |
| US20100297762A1 (en) | 2010-11-25 |
| WO2006111971A2 (en) | 2006-10-26 |
| CA2605617A1 (en) | 2006-10-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |