ATE52258T1 - Verfahren zur herstellung von 2-beta-dribofuranosylselenazol-4-carboxamid. - Google Patents
Verfahren zur herstellung von 2-beta-dribofuranosylselenazol-4-carboxamid.Info
- Publication number
- ATE52258T1 ATE52258T1 AT85304710T AT85304710T ATE52258T1 AT E52258 T1 ATE52258 T1 AT E52258T1 AT 85304710 T AT85304710 T AT 85304710T AT 85304710 T AT85304710 T AT 85304710T AT E52258 T1 ATE52258 T1 AT E52258T1
- Authority
- AT
- Austria
- Prior art keywords
- benzoyl
- tri
- ribofuranosyl
- carboxamide
- ethyl
- Prior art date
Links
- CKMBACZHCFMPLQ-DBRKOABJSA-N 2-[(2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-selenazole-4-carboxamide Chemical compound NC(=O)C1=C[se]C([C@H]2[C@@H]([C@H](O)[C@@H](CO)O2)O)=N1 CKMBACZHCFMPLQ-DBRKOABJSA-N 0.000 abstract 2
- 238000001311 chemical methods and process Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- PALBNLWRVAKKMO-FPCALVHFSA-N ethyl 2-[(2r,3r,4r,5r)-3,4-dibenzoyloxy-5-(benzoyloxymethyl)oxolan-2-yl]-1,3-selenazole-4-carboxylate Chemical compound CCOC(=O)C1=C[se]C([C@H]2[C@@H]([C@H](OC(=O)C=3C=CC=CC=3)[C@@H](COC(=O)C=3C=CC=CC=3)O2)OC(=O)C=2C=CC=CC=2)=N1 PALBNLWRVAKKMO-FPCALVHFSA-N 0.000 abstract 1
- VICYTAYPKBLQFB-UHFFFAOYSA-N ethyl 3-bromo-2-oxopropanoate Chemical compound CCOC(=O)C(=O)CBr VICYTAYPKBLQFB-UHFFFAOYSA-N 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- SPVXKVOXSXTJOY-UHFFFAOYSA-N selane Chemical compound [SeH2] SPVXKVOXSXTJOY-UHFFFAOYSA-N 0.000 abstract 1
- 229910000058 selane Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D421/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms
- C07D421/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms containing two hetero rings
- C07D421/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/629,287 US4619996A (en) | 1984-07-09 | 1984-07-09 | Process for preparing 2-β-D-ribofuranosylselenazole-4-carboxamide |
| EP85304710A EP0171171B1 (de) | 1984-07-09 | 1985-07-02 | Verfahren zur Herstellung von 2-beta-D-Ribofuranosylselenazol-4-carboxamid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE52258T1 true ATE52258T1 (de) | 1990-05-15 |
Family
ID=24522371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85304710T ATE52258T1 (de) | 1984-07-09 | 1985-07-02 | Verfahren zur herstellung von 2-beta-dribofuranosylselenazol-4-carboxamid. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4619996A (de) |
| EP (1) | EP0171171B1 (de) |
| JP (1) | JPS6136293A (de) |
| AT (1) | ATE52258T1 (de) |
| DE (1) | DE3577314D1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5393879A (en) * | 1992-08-17 | 1995-02-28 | The Scripps Research Institute | Fructosyl C-glycoside nucleoside analogs |
| JP2002501546A (ja) * | 1997-06-30 | 2002-01-15 | アイ・シー・エヌ・フアーマシユーテイカルズ・インコーポレイテツド | チアゾフリンおよびその他のｃ−ヌクレオシドを作製する方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4161582A (en) * | 1976-11-22 | 1979-07-17 | Hoffman-La Roche Inc. | Process to produce oxazinomycin |
| US4531001A (en) * | 1982-03-23 | 1985-07-23 | Brigham Young University | 2-β-D-ribofuranosylselenazole-4-carboxamide compounds |
-
1984
- 1984-07-09 US US06/629,287 patent/US4619996A/en not_active Expired - Lifetime
-
1985
- 1985-07-02 EP EP85304710A patent/EP0171171B1/de not_active Expired - Lifetime
- 1985-07-02 DE DE8585304710T patent/DE3577314D1/de not_active Expired - Fee Related
- 1985-07-02 AT AT85304710T patent/ATE52258T1/de not_active IP Right Cessation
- 1985-07-08 JP JP14845385A patent/JPS6136293A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE3577314D1 (de) | 1990-05-31 |
| EP0171171A1 (de) | 1986-02-12 |
| JPS6136293A (ja) | 1986-02-20 |
| EP0171171B1 (de) | 1990-04-25 |
| US4619996A (en) | 1986-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |