ATE514773T1 - Humane zelllinien die eine stabile produktion von cytochrom p450 aufweisen - Google Patents

Humane zelllinien die eine stabile produktion von cytochrom p450 aufweisen

Info

Publication number
ATE514773T1
ATE514773T1 AT00921054T AT00921054T ATE514773T1 AT E514773 T1 ATE514773 T1 AT E514773T1 AT 00921054 T AT00921054 T AT 00921054T AT 00921054 T AT00921054 T AT 00921054T AT E514773 T1 ATE514773 T1 AT E514773T1
Authority
AT
Austria
Prior art keywords
cell lines
cytochrome
human cell
stable production
exhibit stable
Prior art date
Application number
AT00921054T
Other languages
English (en)
Inventor
Masayoshi Nanba
Satoru Asahi
Sumie Yoshitomi
Keiko Ikemoto
Original Assignee
Takeda Pharmaceutical
Masayoshi Nanba
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical, Masayoshi Nanba filed Critical Takeda Pharmaceutical
Application granted granted Critical
Publication of ATE514773T1 publication Critical patent/ATE514773T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/795—Porphyrin- or corrin-ring-containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/795—Porphyrin- or corrin-ring-containing peptides
    • G01N2333/80—Cytochromes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/90245—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
AT00921054T 1999-04-27 2000-04-27 Humane zelllinien die eine stabile produktion von cytochrom p450 aufweisen ATE514773T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12074799 1999-04-27
PCT/JP2000/002763 WO2000065031A1 (fr) 1999-04-27 2000-04-27 Lignee cellulaire humaine presentant une expression stable des cytochromes p450

Publications (1)

Publication Number Publication Date
ATE514773T1 true ATE514773T1 (de) 2011-07-15

Family

ID=14793993

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00921054T ATE514773T1 (de) 1999-04-27 2000-04-27 Humane zelllinien die eine stabile produktion von cytochrom p450 aufweisen

Country Status (6)

Country Link
US (1) US6756229B1 (de)
EP (1) EP1180546B1 (de)
AT (1) ATE514773T1 (de)
AU (1) AU4143200A (de)
CA (1) CA2370365A1 (de)
WO (1) WO2000065031A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE341620T1 (de) 1998-04-28 2006-10-15 Takeda Pharmaceutical Neue, immortalisierte leber-zelllinie humanen ursprungs
US6826737B2 (en) * 2000-12-06 2004-11-30 Cadence Design Systems, Inc. Recursive partitioning placement method and apparatus
US20040096874A1 (en) * 2002-04-11 2004-05-20 Third Wave Technologies, Inc. Characterization of CYP 2D6 genotypes
US7262293B2 (en) * 2003-07-02 2007-08-28 Corus Pharma Aztreonam L-lysine and methods for the preparation thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5506131A (en) 1987-06-05 1996-04-09 The United States Of America As Represented By The Department Of Health And Human Services Immortalized human cell lines containing exogenous cytochrome P450 genes
FR2738840B1 (fr) 1995-09-19 1997-10-31 Rhone Poulenc Rorer Sa Souches de levures genetiquement modifiees

Also Published As

Publication number Publication date
EP1180546A1 (de) 2002-02-20
AU4143200A (en) 2000-11-10
EP1180546A4 (de) 2002-07-31
US6756229B1 (en) 2004-06-29
WO2000065031A1 (fr) 2000-11-02
EP1180546B1 (de) 2011-06-29
CA2370365A1 (en) 2000-11-02

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