ATE513054T1 - METHOD FOR THE ENZYMATIC PRODUCTION OF CITRONELLAL - Google Patents

METHOD FOR THE ENZYMATIC PRODUCTION OF CITRONELLAL

Info

Publication number
ATE513054T1
ATE513054T1 AT06841443T AT06841443T ATE513054T1 AT E513054 T1 ATE513054 T1 AT E513054T1 AT 06841443 T AT06841443 T AT 06841443T AT 06841443 T AT06841443 T AT 06841443T AT E513054 T1 ATE513054 T1 AT E513054T1
Authority
AT
Austria
Prior art keywords
seq
polypeptide sequence
citronellal
aldehyde
enzymatic production
Prior art date
Application number
AT06841443T
Other languages
German (de)
Inventor
Andreas Schaedler
Thomas Friedrich
Rainer Stuermer
Sabine Rinck-Jahnke
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Application granted granted Critical
Publication of ATE513054T1 publication Critical patent/ATE513054T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)

Abstract

Preparation of an optically active saturated aldehyde or alcohol (II) comprises reduction of alpha , beta unsaturated aldehyde (I) with a polypeptide sequence (SEQ ID NO: 1 or 2), or a polypeptide sequence exhibiting at least 80% sequence identity of (SEQ ID NO: 1 or 2), in the presence of an enoate reductase. Preparation of an optically active saturated aldehyde or alcohol of formula (II) comprises reduction of alpha , beta unsaturated aldehyde (I) of formula (R 3>-C(R 2>)=C(R 1>)-CH(=O)) with a polypeptide sequence (SEQ ID NO: 1 or 2) (not defined), or a polypeptide sequence exhibiting at least 80% sequence identity of (SEQ ID NO: 1 or 2), in the presence of a enoate reductase. R 1>, R 2>H or 1-4C-alkyl; and R 3>H or 1-6C alkyl or alkenyl. [Image].
AT06841443T 2005-12-30 2006-12-19 METHOD FOR THE ENZYMATIC PRODUCTION OF CITRONELLAL ATE513054T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005063191A DE102005063191A1 (en) 2005-12-30 2005-12-30 Preparation of an optically active saturated aldehyde or alcohol comprises reduction of alpha, beta unsaturated aldehyde with a polypeptide sequence, in the presence of a enoate reductase
PCT/EP2006/069894 WO2007077121A1 (en) 2005-12-30 2006-12-19 Process for the enzymatic preparation of citronellal

Publications (1)

Publication Number Publication Date
ATE513054T1 true ATE513054T1 (en) 2011-07-15

Family

ID=37882426

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06841443T ATE513054T1 (en) 2005-12-30 2006-12-19 METHOD FOR THE ENZYMATIC PRODUCTION OF CITRONELLAL

Country Status (8)

Country Link
US (1) US8206957B2 (en)
EP (1) EP1974045B1 (en)
JP (1) JP5705410B2 (en)
CN (1) CN101331233B (en)
AT (1) ATE513054T1 (en)
DE (1) DE102005063191A1 (en)
ES (1) ES2367847T3 (en)
WO (1) WO2007077121A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2171077B1 (en) * 2007-07-11 2012-11-28 DSM IP Assets B.V. Enantioselective reduction
TW201000635A (en) * 2008-05-20 2010-01-01 Dsm Ip Assets Bv Preparation of epsilon-caprolactam from (Z)-6,7-dihydro-1H-azepin-2(5H)-one
EP2123767A1 (en) * 2008-05-20 2009-11-25 DSM IP Assets B.V. Preparation of epsilon-caprolactam via lysine cyclisation
WO2010139651A2 (en) 2009-06-04 2010-12-09 Basf Se A process for the enzymatic reduction of enoates
CN111699247A (en) 2017-12-07 2020-09-22 齐默尔根公司 Engineered biosynthetic pathway for the production of (6E) -8-hydroxygeraniol by fermentation
WO2019126778A1 (en) 2017-12-21 2019-06-27 Zymergen Inc. Nepetalactol oxidoreductases, nepetalactol synthases, and microbes capable of producing nepetalactone
WO2020128644A1 (en) * 2018-12-18 2020-06-25 Tojo Vikas Biotech Pvt. Ltd. A process for bio-transformation and production of d-lactones thereof
CN111454918B (en) * 2020-03-10 2022-05-24 浙江工业大学 Enol reductase mutant and application thereof in preparation of (R) -citronellal
CN113337450B (en) * 2021-04-25 2023-03-31 华东理工大学 Escherichia coli genetic engineering bacterium, construction method and method for producing (R) -citronellal through whole-cell catalysis
CN114807247B (en) * 2022-04-29 2023-08-11 苏州百福安酶技术有限公司 Application of candida ludwigii in catalyzing citral to generate dextro citronellal and method for preparing levo isopulegol

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63137685A (en) * 1986-11-29 1988-06-09 Agency Of Ind Science & Technol Production of l-menthol
JPH03103185A (en) * 1989-09-19 1991-04-30 Nippon Oil Co Ltd Production of isoolefin compound
JPH0898696A (en) * 1994-09-30 1996-04-16 Fuji Oil Co Ltd Production of compound by microorganism
EP1557459A1 (en) * 1997-09-09 2005-07-27 Cerveceria Polar, Ca Malt beverage having stabilized flavour and methods of production thereof
DE10019377A1 (en) 2000-04-19 2001-10-25 Basf Ag Immobilization of biologically active substances, especially enzymes, comprises contacting a foamed polymeric material with the substance
JP4213524B2 (en) * 2003-04-17 2009-01-21 ダイセル化学工業株式会社 Novel carbonyl reductase, polynucleotide containing DNA encoding the enzyme, method for producing the same, and method for producing optically active alcohol using the same
CN1232493C (en) * 2004-02-20 2005-12-21 中国科学院广州化学研究所 Synthesis process of methoxy citronellal

Also Published As

Publication number Publication date
JP5705410B2 (en) 2015-04-22
JP2009521915A (en) 2009-06-11
EP1974045B1 (en) 2011-06-15
US8206957B2 (en) 2012-06-26
WO2007077121A1 (en) 2007-07-12
US20080293111A1 (en) 2008-11-27
CN101331233B (en) 2012-09-05
CN101331233A (en) 2008-12-24
ES2367847T3 (en) 2011-11-10
EP1974045A1 (en) 2008-10-01
DE102005063191A1 (en) 2007-07-05

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