ATE512185T1 - Heterobifunktionelle polyethylenglycol-reagenzien - Google Patents

Heterobifunktionelle polyethylenglycol-reagenzien

Info

Publication number
ATE512185T1
ATE512185T1 AT08848988T AT08848988T ATE512185T1 AT E512185 T1 ATE512185 T1 AT E512185T1 AT 08848988 T AT08848988 T AT 08848988T AT 08848988 T AT08848988 T AT 08848988T AT E512185 T1 ATE512185 T1 AT E512185T1
Authority
AT
Austria
Prior art keywords
polyethylene glycol
heterobifunctional polyethylene
glycol reagents
reagents
heterobifunctional
Prior art date
Application number
AT08848988T
Other languages
English (en)
Inventor
Daniel E Levy
Samuel Zalipsky
Steven M Chamow
Original Assignee
Intradigm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intradigm Corp filed Critical Intradigm Corp
Application granted granted Critical
Publication of ATE512185T1 publication Critical patent/ATE512185T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32Polymers modified by chemical after-treatment
    • C08G65/329Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/332Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
    • C08G65/3322Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof acyclic
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32Polymers modified by chemical after-treatment
    • C08G65/329Polymers modified by chemical after-treatment with organic compounds
    • C08G65/333Polymers modified by chemical after-treatment with organic compounds containing nitrogen
    • C08G65/33303Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing amino group
    • C08G65/33306Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing amino group acyclic
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32Polymers modified by chemical after-treatment
    • C08G65/329Polymers modified by chemical after-treatment with organic compounds
    • C08G65/333Polymers modified by chemical after-treatment with organic compounds containing nitrogen
    • C08G65/33331Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing imide group
    • C08G65/33337Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing imide group cyclic
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32Polymers modified by chemical after-treatment
    • C08G65/329Polymers modified by chemical after-treatment with organic compounds
    • C08G65/333Polymers modified by chemical after-treatment with organic compounds containing nitrogen
    • C08G65/33379Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing nitro group
    • C08G65/33386Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing nitro group cyclic
    • C08G65/33389Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing nitro group cyclic aromatic
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32Polymers modified by chemical after-treatment
    • C08G65/329Polymers modified by chemical after-treatment with organic compounds
    • C08G65/334Polymers modified by chemical after-treatment with organic compounds containing sulfur
    • C08G65/3344Polymers modified by chemical after-treatment with organic compounds containing sulfur containing oxygen in addition to sulfur
    • C08G65/3346Polymers modified by chemical after-treatment with organic compounds containing sulfur containing oxygen in addition to sulfur having sulfur bound to carbon and oxygen
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32Polymers modified by chemical after-treatment
    • C08G65/329Polymers modified by chemical after-treatment with organic compounds
    • C08G65/337Polymers modified by chemical after-treatment with organic compounds containing other elements

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Polyethers (AREA)
AT08848988T 2007-11-12 2008-11-12 Heterobifunktionelle polyethylenglycol-reagenzien ATE512185T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US285307P 2007-11-12 2007-11-12
PCT/US2008/012782 WO2009064459A2 (en) 2007-11-12 2008-11-12 Heterobifunctional polyethylene glycol reagents

Publications (1)

Publication Number Publication Date
ATE512185T1 true ATE512185T1 (de) 2011-06-15

Family

ID=40639391

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08848988T ATE512185T1 (de) 2007-11-12 2008-11-12 Heterobifunktionelle polyethylenglycol-reagenzien

Country Status (7)

Country Link
US (1) US20110282093A1 (de)
EP (1) EP2209834B1 (de)
JP (1) JP2011504463A (de)
CN (1) CN101903439A (de)
AT (1) ATE512185T1 (de)
CA (1) CA2705521A1 (de)
WO (1) WO2009064459A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102010034331A1 (de) 2010-08-14 2012-02-16 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Polymer-gestützte Kultursysteme
US9591854B2 (en) 2012-06-18 2017-03-14 Basf Se Agroformulations containing a lactone based alkoxylate
WO2014138720A1 (en) * 2013-03-08 2014-09-12 University Of Southern California Usc Stevens Vinylsulfone-based 18f-labeling compositions and methods and uses thereof
EP3958983A1 (de) 2019-04-26 2022-03-02 The Procter & Gamble Company Reduktion von zahnverfärbung aus kationischen antimikrobiellen mitteln

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5446090A (en) * 1993-11-12 1995-08-29 Shearwater Polymers, Inc. Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules
US6309646B1 (en) * 1996-05-09 2001-10-30 The Henry M. Jackson Foundation For The Advancement Of Military Medicine Protein-polysaccharide conjugate vaccines and other immunological reagents prepared using homobifunctional and heterobifunctional vinylsulfones, and processes for preparing the conjugates

Also Published As

Publication number Publication date
EP2209834A2 (de) 2010-07-28
JP2011504463A (ja) 2011-02-10
WO2009064459A3 (en) 2009-08-13
EP2209834B1 (de) 2011-06-08
WO2009064459A2 (en) 2009-05-22
US20110282093A1 (en) 2011-11-17
CA2705521A1 (en) 2009-05-22
CN101903439A (zh) 2010-12-01

Similar Documents

Publication Publication Date Title
CL2009001263S1 (es) Maquina de afeitar.
MX2020001497A (es) Sintesis de gamma-carbolinas fusionadas con heterociclo substituido.
CY1116261T1 (el) Αντισωματα και ανοσοσυζευγματα και χρησεις αυτων
MX345909B (es) Anticuerpos anti-fgfr3 y métodos que los utilizan.
CY1121742T1 (el) Αντισωματα s100a4 και θεραπευτικες χρησεις αυτων
DE602006006200D1 (de) Antikörper gegen 25-hydroxyvitamin d
PH12013502230A1 (en) Multispecific antibodies
MX2010006396A (es) Anticuerpos bivalentes, biespecificos.
MX2010005682A (es) Anticuerpos bivalentes, biespecificos.
MX2010005888A (es) Anticuerpos bivalentes biespecificos.
UA100874C2 (en) Bivalent bispecific antibodies
EP2493506A4 (de) Il-17a-antagonisten
CL2007002182S1 (es) Terminal.
EP2569330A4 (de) Chlorotoxin-varianten und -konjugate sowie verfahren zu ihrer verwendung
CY1114023T1 (el) Διυποκατεστημενης φθαλαζινης ανταγωνιστες σηματοδοτικης οδου hedgehog
CO6241120A2 (es) (DIHIDRO)PIRROLO[2,1-á]ISOQUINOLINAS.
ECSP11011190A (es) Anticuerpos monoclonales anti-rhd
BR112012000427A2 (pt) formação de feixe utilizando livros de códigos de base e diferenciais.
ATE512185T1 (de) Heterobifunktionelle polyethylenglycol-reagenzien
EA200971067A1 (ru) Триазолиламинопиримидиновые соединения
AU321758S (en) Images and sound editor
CR10651A (es) Derivados de feniloxianilina
UA112066C2 (uk) Способи отримання енамінів
TR201105080T2 (tr) Özet başlığı bulunamadı.
UA109564C2 (xx) Способи отримання енамінів

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties