ATE511399T1 - COMBINATION OF AN ANTI-EDB FIBRONECTIN DOMAIN ANTIBODY L19-SIP AND AN ANTI-EGFR ANTIBODY - Google Patents

COMBINATION OF AN ANTI-EDB FIBRONECTIN DOMAIN ANTIBODY L19-SIP AND AN ANTI-EGFR ANTIBODY

Info

Publication number
ATE511399T1
ATE511399T1 AT07724950T AT07724950T ATE511399T1 AT E511399 T1 ATE511399 T1 AT E511399T1 AT 07724950 T AT07724950 T AT 07724950T AT 07724950 T AT07724950 T AT 07724950T AT E511399 T1 ATE511399 T1 AT E511399T1
Authority
AT
Austria
Prior art keywords
antibody
sip
combination
fibronectin domain
edb fibronectin
Prior art date
Application number
AT07724950T
Other languages
German (de)
Inventor
Stephanie Sieger
Dietmar Berndorff
Ludger Dinkelborg
Bernhard Tijink
DONGEN Augustinus VAN
Original Assignee
Bayer Schering Pharma Ag
Vereniging Vu Windesheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag, Vereniging Vu Windesheim filed Critical Bayer Schering Pharma Ag
Priority claimed from PCT/EP2007/004026 external-priority patent/WO2007128557A1/en
Application granted granted Critical
Publication of ATE511399T1 publication Critical patent/ATE511399T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
AT07724950T 2006-05-03 2007-04-26 COMBINATION OF AN ANTI-EDB FIBRONECTIN DOMAIN ANTIBODY L19-SIP AND AN ANTI-EGFR ANTIBODY ATE511399T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06090067 2006-05-03
US80001106P 2006-05-15 2006-05-15
PCT/EP2007/004026 WO2007128557A1 (en) 2006-05-03 2007-04-26 Combination of an anti edb fibronectin domain antibody l19-sip and an anti-egfr antibody

Publications (1)

Publication Number Publication Date
ATE511399T1 true ATE511399T1 (en) 2011-06-15

Family

ID=37116182

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07724950T ATE511399T1 (en) 2006-05-03 2007-04-26 COMBINATION OF AN ANTI-EDB FIBRONECTIN DOMAIN ANTIBODY L19-SIP AND AN ANTI-EGFR ANTIBODY

Country Status (1)

Country Link
AT (1) ATE511399T1 (en)

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties