ATE503T1 - HEART AND KIDNEY PROTECTIVE SOLUTION AND PROCESS FOR PRODUCTION. - Google Patents

HEART AND KIDNEY PROTECTIVE SOLUTION AND PROCESS FOR PRODUCTION.

Info

Publication number
ATE503T1
ATE503T1 AT79104734T AT79104734T ATE503T1 AT E503 T1 ATE503 T1 AT E503T1 AT 79104734 T AT79104734 T AT 79104734T AT 79104734 T AT79104734 T AT 79104734T AT E503 T1 ATE503 T1 AT E503T1
Authority
AT
Austria
Prior art keywords
millimols
heart
solution
production
protective solution
Prior art date
Application number
AT79104734T
Other languages
German (de)
Inventor
Hans-Juergen Prof. Dr. Bretschneider
Original Assignee
Dr. Franz Koehler Chemie Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr. Franz Koehler Chemie Kg filed Critical Dr. Franz Koehler Chemie Kg
Application granted granted Critical
Publication of ATE503T1 publication Critical patent/ATE503T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)

Abstract

1. Protective solution for preventing ischaemia damage to the heart and kidneys and other organs in the course of operations and transplantations of these organs whilst the blood circulation is shut out, characterised in that it consists of a buffer system based on 150 +- 100 millimols of histidine, 16 +- 10 millimols of histidine hydrochloride and 2 +- 1 millimols of tryptophane per litre, which additionally contains alkali metal ions and alkaline earth metal ions as well as a polyol or a sugar, the sum of the cations being 25-80 milliequivalents, the osmolarity of the solution being 300-400 mosm and the pH of the solution being between 6.6 and 7.6.
AT79104734T 1978-12-14 1979-11-28 HEART AND KIDNEY PROTECTIVE SOLUTION AND PROCESS FOR PRODUCTION. ATE503T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1275778A CH639270A5 (en) 1978-12-14 1978-12-14 PROTECTIVE SOLUTION FOR HEART AND KIDNEY.
EP79104734A EP0012272B1 (en) 1978-12-14 1979-11-28 Protecting solution for heart and kidneys and process for its manufacture

Publications (1)

Publication Number Publication Date
ATE503T1 true ATE503T1 (en) 1982-01-15

Family

ID=4386118

Family Applications (1)

Application Number Title Priority Date Filing Date
AT79104734T ATE503T1 (en) 1978-12-14 1979-11-28 HEART AND KIDNEY PROTECTIVE SOLUTION AND PROCESS FOR PRODUCTION.

Country Status (4)

Country Link
EP (1) EP0012272B1 (en)
AT (1) ATE503T1 (en)
CH (1) CH639270A5 (en)
DE (1) DE2961723D1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE11736T1 (en) * 1980-12-23 1985-02-15 Dr. Franz Koehler Chemie Gmbh HEART AND KIDNEY PROTECTIVE SOLUTION AND PROCESS FOR PRODUCTION.
SE8403912D0 (en) * 1984-07-30 1984-07-30 Pharmacia Ab PHARMACEUTICAL KIT OR COMPOSITION
FR2602677B1 (en) * 1986-08-14 1992-03-06 Blomet Marie Claude PHYSIOLOGICAL SOLUTION FOR WASHING PARTS OF THE HUMAN OR ANIMAL BODY WHICH HAVE BEEN IN CONTACT WITH AN ACID OR A BASE, AND CONCENTRATED FOR ITS PREPARATION
US5092838A (en) * 1989-11-30 1992-03-03 Baxter International Inc. Histidine buffered peritoneal dialysis solution
US5290766A (en) * 1991-02-18 1994-03-01 The National Heart Foundation Of New Zealand Cardioplegic compositions
FR2715028B1 (en) * 1994-01-17 1998-01-16 Christine Charrueau Compositions for organ preservation.
DE10222561B4 (en) 2002-05-17 2009-12-10 Dr. Franz Köhler Chemie GmbH Protective solution for the prevention of ischemic damage
DE102007026392A1 (en) 2007-06-06 2008-12-11 Bayer Healthcare Ag Solutions for the perfusion and preservation of organs and tissues

Also Published As

Publication number Publication date
EP0012272A1 (en) 1980-06-25
DE2961723D1 (en) 1982-02-18
EP0012272B1 (en) 1981-12-30
CH639270A5 (en) 1983-11-15

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Legal Events

Date Code Title Description
EELA Cancelled due to lapse of time