ATE502049T1 - Peptide und polypeptide mit verbesserter stabilität, die sich für die regeneration des nervensystems eignen - Google Patents
Peptide und polypeptide mit verbesserter stabilität, die sich für die regeneration des nervensystems eignenInfo
- Publication number
- ATE502049T1 ATE502049T1 AT07872378T AT07872378T ATE502049T1 AT E502049 T1 ATE502049 T1 AT E502049T1 AT 07872378 T AT07872378 T AT 07872378T AT 07872378 T AT07872378 T AT 07872378T AT E502049 T1 ATE502049 T1 AT E502049T1
- Authority
- AT
- Austria
- Prior art keywords
- ser
- trp
- seq
- peptides
- cys
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 210000000653 nervous system Anatomy 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 230000008929 regeneration Effects 0.000 title 1
- 238000011069 regeneration method Methods 0.000 title 1
- IJYZHIOOBGIINM-WDSKDSINSA-N Arg-Ser Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@@H](N)CCCN=C(N)N IJYZHIOOBGIINM-WDSKDSINSA-N 0.000 abstract 1
- 206010029260 Neuroblastoma Diseases 0.000 abstract 1
- 102000002938 Thrombospondin Human genes 0.000 abstract 1
- 108060008245 Thrombospondin Proteins 0.000 abstract 1
- MYVYPSWUSKCCHG-JQWIXIFHSA-N Trp-Ser Chemical compound C1=CC=C2C(C[C@H](N)C(=O)N[C@@H](CO)C(O)=O)=CNC2=C1 MYVYPSWUSKCCHG-JQWIXIFHSA-N 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 230000005709 nerve cell growth Effects 0.000 abstract 1
- 210000002241 neurite Anatomy 0.000 abstract 1
- 230000000324 neuroprotective effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0611005A FR2910003B1 (fr) | 2006-12-18 | 2006-12-18 | Nouveaux peptides et polypeptides a stabilite amelioree utiles dans la regeneration du systeme nerveux |
| PCT/FR2007/002089 WO2008090285A2 (fr) | 2006-12-18 | 2007-12-17 | Nouveaux peptides et polypeptides à stabilité améliorée utiles dans la régénération du système nerveux |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE502049T1 true ATE502049T1 (de) | 2011-04-15 |
Family
ID=38229608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07872378T ATE502049T1 (de) | 2006-12-18 | 2007-12-17 | Peptide und polypeptide mit verbesserter stabilität, die sich für die regeneration des nervensystems eignen |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP2118137B1 (de) |
| AT (1) | ATE502049T1 (de) |
| DE (1) | DE602007013289D1 (de) |
| ES (1) | ES2363676T3 (de) |
| FR (1) | FR2910003B1 (de) |
| WO (1) | WO2008090285A2 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3041644B1 (fr) | 2015-09-25 | 2018-01-05 | Neuronax | Polypeptides cycliques, leur procede d'obtention et leur application en therapeutique |
| EP3330284A1 (de) | 2016-12-05 | 2018-06-06 | Neuronax Sa | Verwendung von peptidverbindungen zur förderung des überlebens, des wachstums und der zelldifferenzierung |
| EP3360884A1 (de) | 2017-02-10 | 2018-08-15 | Neuronax | Verbessertes verfahren zur herstellung eines dodecapeptids |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5840692A (en) * | 1990-02-22 | 1998-11-24 | Allegheny University Of The Health Sciences | Peptide fragments and analogs of thrombospondin |
| FR2766190B1 (fr) * | 1997-07-16 | 2001-11-02 | Univ Clermont Auvergne | Nouveaux peptides et polypeptides utiles dans la regeneration du systeme nerveux |
-
2006
- 2006-12-18 FR FR0611005A patent/FR2910003B1/fr not_active Expired - Fee Related
-
2007
- 2007-12-17 DE DE602007013289T patent/DE602007013289D1/de active Active
- 2007-12-17 ES ES07872378T patent/ES2363676T3/es active Active
- 2007-12-17 WO PCT/FR2007/002089 patent/WO2008090285A2/fr active Application Filing
- 2007-12-17 AT AT07872378T patent/ATE502049T1/de not_active IP Right Cessation
- 2007-12-17 EP EP07872378A patent/EP2118137B1/de not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| EP2118137A2 (de) | 2009-11-18 |
| DE602007013289D1 (de) | 2011-04-28 |
| ES2363676T3 (es) | 2011-08-11 |
| EP2118137B1 (de) | 2011-03-16 |
| WO2008090285A2 (fr) | 2008-07-31 |
| FR2910003B1 (fr) | 2012-10-26 |
| FR2910003A1 (fr) | 2008-06-20 |
| WO2008090285A3 (fr) | 2008-10-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |