ATE477558T1 - FEATURES-BASED REGISTRATION OF SECTIONAL PICTURES - Google Patents
FEATURES-BASED REGISTRATION OF SECTIONAL PICTURESInfo
- Publication number
- ATE477558T1 ATE477558T1 AT07817967T AT07817967T ATE477558T1 AT E477558 T1 ATE477558 T1 AT E477558T1 AT 07817967 T AT07817967 T AT 07817967T AT 07817967 T AT07817967 T AT 07817967T AT E477558 T1 ATE477558 T1 AT E477558T1
- Authority
- AT
- Austria
- Prior art keywords
- image
- features
- specimen
- sections
- based registration
- Prior art date
Links
- 230000009466 transformation Effects 0.000 abstract 2
Classifications
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/0002—Inspection of images, e.g. flaw detection
- G06T7/0012—Biomedical image inspection
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T3/00—Geometric image transformations in the plane of the image
- G06T3/14—Transformations for image registration, e.g. adjusting or mapping for alignment of images
- G06T3/153—Transformations for image registration, e.g. adjusting or mapping for alignment of images using elastic snapping
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/30—Determination of transform parameters for the alignment of images, i.e. image registration
- G06T7/33—Determination of transform parameters for the alignment of images, i.e. image registration using feature-based methods
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H30/00—ICT specially adapted for the handling or processing of medical images
- G16H30/20—ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H30/00—ICT specially adapted for the handling or processing of medical images
- G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Theoretical Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Medical Informatics (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Primary Health Care (AREA)
- Public Health (AREA)
- Quality & Reliability (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Image Processing (AREA)
- Image Analysis (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Display Devices Of Pinball Game Machines (AREA)
- Management Or Editing Of Information On Record Carriers (AREA)
Abstract
The present invention relates to a method and a system for obtaining and analysing image pairs, obtained as sections of specimen. The invention facilitates registration of two corresponding images, one from each section of the specimen. The invention includes performing a registration process of the two images thereby obtaining a mathematical transformation rule and afterwards using said transformation rule for each image field identified in one image allowing that the corresponding image field in the other image may be identified as well. After the corresponding image pairs have been obtained using the method of the present invention, the sections can be assessed, such as by identifying the counting events for at least one type of object on the image fields within at least one corresponding image pair, optionally using automatic means.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200601507 | 2006-11-16 | ||
US87808207P | 2007-01-03 | 2007-01-03 | |
PCT/DK2007/050171 WO2008080403A1 (en) | 2006-11-16 | 2007-11-16 | Feature-based registration of sectional images |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE477558T1 true ATE477558T1 (en) | 2010-08-15 |
Family
ID=39076944
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07817967T ATE477558T1 (en) | 2006-11-16 | 2007-11-16 | FEATURES-BASED REGISTRATION OF SECTIONAL PICTURES |
Country Status (7)
Country | Link |
---|---|
US (2) | US8229194B2 (en) |
EP (1) | EP2095332B1 (en) |
JP (1) | JP2010511213A (en) |
CN (1) | CN101542527A (en) |
AT (1) | ATE477558T1 (en) |
DE (1) | DE602007008464D1 (en) |
WO (1) | WO2008080403A1 (en) |
Families Citing this family (50)
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US9697582B2 (en) * | 2006-11-16 | 2017-07-04 | Visiopharm A/S | Methods for obtaining and analyzing images |
GB0900191D0 (en) * | 2009-01-07 | 2009-02-11 | Ge Healthcare Uk Ltd | Microscopy |
BRPI1007627A2 (en) * | 2009-04-28 | 2018-03-06 | Koninklijke Philips Electrnics N. V. | method for use in biology, histology and pathology, equipment or system for use in biology, histology and pathology data support and information processing systems for use in biology histology and pathology |
JP5829612B2 (en) | 2009-10-22 | 2015-12-09 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | Ordered stack alignment of images from specimens |
US8995790B2 (en) * | 2010-06-15 | 2015-03-31 | Koninklijke Philips N.V. | Image processing method in microscopy |
US8787651B2 (en) * | 2010-09-28 | 2014-07-22 | Flagship Biosciences, LLC | Methods for feature analysis on consecutive tissue sections |
WO2012097189A1 (en) * | 2011-01-13 | 2012-07-19 | Rutgers, The State University Of New Jersey | Systems and methods for multi-protocol registration and tissue classification using local morphologic scale (lms) |
WO2012123861A1 (en) * | 2011-03-15 | 2012-09-20 | Koninklijke Philips Electronics N.V. | Correlated image mapping pointer |
US9159129B2 (en) | 2011-07-12 | 2015-10-13 | Definiens Ag | Generating image-based diagnostic tests by optimizing image analysis and data mining of co-registered images |
US8699769B2 (en) * | 2011-07-12 | 2014-04-15 | Definiens Ag | Generating artificial hyperspectral images using correlated analysis of co-registered images |
JP5780306B2 (en) * | 2011-08-18 | 2015-09-16 | 日本電気株式会社 | Information processing system, information processing method, information processing apparatus, control method thereof, and control program |
US9740912B2 (en) | 2011-12-20 | 2017-08-22 | Definiens Ag | Evaluation of co-registered images of differently stained tissue slices |
JP6124543B2 (en) * | 2011-12-26 | 2017-05-10 | キヤノン株式会社 | Image processing apparatus, image processing method, image processing system, and program |
WO2013107463A1 (en) * | 2012-01-20 | 2013-07-25 | Visiopharm A/S | System and method for standardized, optimized and pre-configured quantitative digital pathology |
US8755633B2 (en) * | 2012-03-14 | 2014-06-17 | Sony Corporation | Automated synchronized navigation system for digital pathology imaging |
DE102012218382B4 (en) * | 2012-10-09 | 2015-04-23 | Leica Microsystems Cms Gmbh | Method for determining a laser microdissection range and associated laser microdissection system |
US8824758B2 (en) * | 2012-11-07 | 2014-09-02 | Sony Corporation | Method and apparatus for orienting tissue samples for comparison |
US8942447B2 (en) | 2012-11-07 | 2015-01-27 | Sony Corporation | Method and apparatus for tissue region identification |
US10088658B2 (en) | 2013-03-18 | 2018-10-02 | General Electric Company | Referencing in multi-acquisition slide imaging |
US9064304B2 (en) * | 2013-03-18 | 2015-06-23 | General Electric Company | Image quality assessment of microscopy images |
RU2536675C1 (en) * | 2013-05-27 | 2014-12-27 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Южно-Российский государственный университет экономики и сервиса" (ФГБОУ ВПО "ЮРГУЭС") | Apparatus for integrating images into single scene composition |
JP2015031599A (en) * | 2013-08-02 | 2015-02-16 | オリンパス株式会社 | Image superposing method |
US10025479B2 (en) * | 2013-09-25 | 2018-07-17 | Terarecon, Inc. | Advanced medical image processing wizard |
US9436995B2 (en) * | 2014-04-27 | 2016-09-06 | International Business Machines Corporation | Discriminating between normal and abnormal left ventricles in echocardiography |
CA2995719A1 (en) * | 2014-08-18 | 2016-02-25 | Viewsiq Inc. | System and method for embedded images in large field-of-view microscopic scans |
US9740957B2 (en) | 2014-08-29 | 2017-08-22 | Definiens Ag | Learning pixel visual context from object characteristics to generate rich semantic images |
US9805248B2 (en) | 2014-08-29 | 2017-10-31 | Definiens Ag | Applying pixelwise descriptors to a target image that are generated by segmenting objects in other images |
CN105654457A (en) * | 2014-11-14 | 2016-06-08 | 富士通株式会社 | Device and method for processing image |
WO2016181182A1 (en) * | 2015-05-08 | 2016-11-17 | Synaptive Medical (Barbados) Inc. | Magnetic resonance visible labels and markers for encoding information |
DE102015108017A1 (en) * | 2015-05-20 | 2016-11-24 | Leica Microsystems Cms Gmbh | Method and examination system for examining and processing a microscopic sample |
WO2017009450A1 (en) * | 2015-07-16 | 2017-01-19 | Koninklijke Philips N.V. | Digital pathology system |
WO2017013045A1 (en) | 2015-07-17 | 2017-01-26 | Koninklijke Philips N.V. | Registration of histopathology images |
US9741112B2 (en) | 2015-09-10 | 2017-08-22 | Definiens Ag | Generating image-based diagnostic tests by optimizing image analysis and data mining of co-registered images |
CN106725564B (en) * | 2015-11-25 | 2021-08-13 | 东芝医疗系统株式会社 | Image processing apparatus and image processing method |
JP2017164068A (en) * | 2016-03-14 | 2017-09-21 | 富士通株式会社 | Determination device, analysis device, calculation device, determination method, analysis method, calculation method, determination program, analysis program, and calculation program |
DE102016105102A1 (en) * | 2016-03-18 | 2017-09-21 | Leibniz-Institut für Photonische Technologien e. V. | Method for examining distributed objects |
US10438096B2 (en) | 2016-12-27 | 2019-10-08 | Definiens Ag | Identifying and excluding blurred areas of images of stained tissue to improve cancer scoring |
DK3639191T3 (en) | 2017-06-15 | 2021-12-06 | Visiopharm As | Method for training a deep learning model to obtain histopathological information from images |
US10776972B2 (en) * | 2018-04-25 | 2020-09-15 | Cognex Corporation | Systems and methods for stitching sequential images of an object |
EP3814741A4 (en) * | 2018-06-28 | 2022-03-02 | The Regents Of The University Of California | Producing a composite image of a stained tissue sample by combining image data |
US11756203B2 (en) | 2018-09-21 | 2023-09-12 | The Johns Hopkins University | Characterization platform for scalable, spatially-resolved multispectral analysis of tissue |
WO2020152151A1 (en) * | 2019-01-22 | 2020-07-30 | Imabiotech | Method for evaluating molecular changes related to a molecule effect in a biological sample |
JP7193728B2 (en) | 2019-03-15 | 2022-12-21 | 富士通株式会社 | Information processing device and stored image selection method |
EP3761032A1 (en) | 2019-07-03 | 2021-01-06 | Xyall B.V. | Determining region(s) for tissue dissection in pathology slides |
CN113125434A (en) * | 2019-12-31 | 2021-07-16 | 深圳迈瑞生物医疗电子股份有限公司 | Image analysis system and method of controlling photographing of sample image |
EP3941030B1 (en) * | 2020-07-16 | 2023-05-24 | Nokia Technologies Oy | Apparatus, method and computer program for image capturing |
CN112017123A (en) * | 2020-09-15 | 2020-12-01 | 亚龙智能装备集团股份有限公司 | Imaging method of virtual microscope |
CN112862872B (en) * | 2021-02-05 | 2022-09-06 | 中国科学技术大学 | Automatic registration method of mass spectrum imaging data |
WO2023081490A1 (en) * | 2021-11-08 | 2023-05-11 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Virtual alignment of pathology image series |
CN115861275B (en) * | 2022-12-26 | 2024-02-06 | 中南大学 | Cell counting method, cell counting device, terminal equipment and medium |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4932044A (en) * | 1988-11-04 | 1990-06-05 | Yale University | Tissue analyzer |
GB2398379A (en) * | 2003-02-11 | 2004-08-18 | Qinetiq Ltd | Automated digital image analysis |
ATE553458T1 (en) * | 2006-12-15 | 2012-04-15 | Univ Aarhus | METHOD FOR UNPRESENTATIVE ESTIMATION OF TOTAL SET OF OBJECTS BASED ON NON-UNIFORM SAMPLES WITH PROBABILITY OBTAINED BY USING IMAGE ANALYSIS |
US20090304244A1 (en) * | 2008-06-06 | 2009-12-10 | Applied Spectral Imaging Ltd. | Method and a system for presenting sections of a histological specimen |
-
2007
- 2007-11-16 WO PCT/DK2007/050171 patent/WO2008080403A1/en active Application Filing
- 2007-11-16 CN CNA2007800427151A patent/CN101542527A/en active Pending
- 2007-11-16 DE DE602007008464T patent/DE602007008464D1/en active Active
- 2007-11-16 US US12/514,918 patent/US8229194B2/en active Active
- 2007-11-16 EP EP07817967A patent/EP2095332B1/en active Active
- 2007-11-16 AT AT07817967T patent/ATE477558T1/en not_active IP Right Cessation
- 2007-11-16 JP JP2009536607A patent/JP2010511213A/en not_active Withdrawn
-
2012
- 2012-06-21 US US13/529,440 patent/US8682050B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20130016892A1 (en) | 2013-01-17 |
DE602007008464D1 (en) | 2010-09-23 |
EP2095332A1 (en) | 2009-09-02 |
US8682050B2 (en) | 2014-03-25 |
US8229194B2 (en) | 2012-07-24 |
WO2008080403A1 (en) | 2008-07-10 |
JP2010511213A (en) | 2010-04-08 |
CN101542527A (en) | 2009-09-23 |
WO2008080403A8 (en) | 2008-11-06 |
EP2095332B1 (en) | 2010-08-11 |
US20100215227A1 (en) | 2010-08-26 |
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